Wyniki wyszukiwania

1

Mechanizmy opornosci Salmonella na chinolony

100%

Wasyl D.

Medycyna Weterynaryjna

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2009

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tom 65

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nr 08

516-520

Shortly after the introduction of fluoroquinolones into human and animal therapy an acquired resistance to these compounds was described in many bacterial species. The primary type of the resistance generally involves multiple point mutations in the genes encoding the quinolone target enzymes: gyrase (gyrA and gyrB) and topoisomerase IV (parC and parE). The frequency of occurrence of Salmonella strains conferring quinolone resistance has recently increased significantly. Moreover, novel plasmid-mediated resistance mechanisms that can spread horizontally were reported. These include the production of enzyme protecting peptides encoded by several alleles of qnr gene (qnrA, qnrB, qnrS, qnrD) and their variants, quinolone efflux pump (qep), and finally ciprofloxacin modification by a variant of aminoglycoside acethyltransferase (aac(6’)-Ib-cr). The paper presents the background of resistance mechanisms as well as the occurrence and global spread of quinolone resistant Salmonella.

2

Antybiotykooporność Campylobacter - aspekty epidemiologiczne i zagrożenie zdrowia publicznego

84%

Wieczorek K., Kania I., Osek J.

Medycyna Weterynaryjna

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2011

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tom 67

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nr 04

Campylobacters are the most common bacterial cause of food-borne gastrointestinal infections in humans in developed countries. Macrolides and fluoroquinolones (FQ) are regarded as drugs of choice for the treatment of campylobacteriosis. Moreover, fluoroquinolones such as ciprofloxacin have been used for the first-line treatment of bacterial gastroenteritis in the absence of confirmed microbiological diagnosis. The fluoroquinolone resistance is mainly caused by a single step point mutation in the gyrase gyrA gene. The major mechanism conferring the resistance to macrolides consists of an alternation of the target site in domain V of the 23S ribosomal RNA gene. During 2004-2008 European Union Member States provided much information to EFSA on the occurrence of antimicrobial resistance in Campylobacter isolated from animals and food. Different resistance levels to antimicrobials was found among the isolates tested. For some antimicrobials, large differences in the occurrence of resistance were observed between the Member States. Some of them reported a high percentage of Campylobacter isolates recovered from poultry, pigs and cattle, as well as from meat resistant to fluoroquinolones. This suggests that due to the use of antimicrobial agents, particularly FQ, in food-producing animals, Campylobacter spp. developed resistance. Resistant strains could be transferred from animals to man by the food chain and constitute a hazard for public health; not all data, however, support this view. Some authors suggest that although some antibiotics are used in both animals and humans, most of the resistance problems in humans have arisen from human medicine. At any rate, a rational and prudent use of antibiotics in both areas is strongly recommended.

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Bakterie fermentacji mlekowej w tym szczepy probiotyczne jako rezerwuar genów oporności na antybiotyki

67%

Chajecka-Wierzchowska W., Zadernowska A.

Żywność Nauka Technologia Jakość

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2019

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tom 26

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nr 3

4

Nowe trendy w leczeniu zakażeń wywołanych przez superbakterie

67%

Glinski Z., Kostro K.

Magazyn Weterynaryjny

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2016

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tom 25

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nr 09

Ograniczanie wyników

2 Medycyna Weterynaryjna

1 Magazyn Weterynaryjny

1 Żywność Nauka Technologia Jakość

1 Chajecka-Wierzchowska W.

1 Glinski Z.

1 Kania I.

1 Kostro K.

1 Osek J.

1 Wasyl D.

1 Wieczorek K.

1 Zadernowska A.

1 2019

1 2016

1 2011

1 2009

Mechanizmy opornosci Salmonella na chinolony

Antybiotykooporność Campylobacter - aspekty epidemiologiczne i zagrożenie zdrowia publicznego

Bakterie fermentacji mlekowej w tym szczepy probiotyczne jako rezerwuar genów oporności na antybiotyki

Nowe trendy w leczeniu zakażeń wywołanych przez superbakterie