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  1. 14 Acta Biologica et Medica

  2. 3 Polish Journal of Veterinary Sciences

  3. 2 Acta Biochimica Polonica

  4. 2 Cellular and Molecular Biology Letters

  5. 2 Folia Histochemica et Cytobiologica

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  1. 3 Kozlowska K.

  2. 3 Krol M.

  3. 3 Motyl T.

  4. 3 Pawlowski K. M.

  5. 3 Zielinska W.

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  1. 1 2016

  2. 1 2015

  3. 2 2012

  4. 2 2010

  5. 1 2008

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1

ALK 5 [TGF beta RI] inhibitors: In-vitro and in-vivo characterization of novel orally active pteridines

100%
Chakravarty S., Dugar S.
Cellular and Molecular Biology Letters
|
2005
|
tom 10
|
nr Suppl.2
2

Powstanie i działalność organizacji do walki z rakiem w Polsce (do 1939 r.)

86%
Supady J. J.
Analecta. Studia i Materiały z Dziejów Nauki
|
2012
|
tom 21
|
nr 1-2
3
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

The role of physical therapy in cancer treatment

86%
Sidor M., Jeziorski K.
Health Problems of Civilization
|
2015
|
tom 09
|
nr 1
Cancer is a very important problem in both medical and social respects. In recent years, there has been a shift in approach to oncological prevention, diagnostics and treatment. As a result, oncology has become an interdisciplinary field. Factors relevant for successful oncological treatment are: sequence, type and scope of intervention, including diagnosis of the cancer, assessment of its progression, systemic treatment, surgery, radiotherapy, supportive therapy and rehabilitation. Rehabilitation addresses the realm of psychology (psychooncology), as well as somatic and social issues. Physical therapy is a notion inseparably related to medical rehabilitation and it encompasses a range of treatments which are based on the body’s reactivity to stimuli. The purpose of this article is to present the specific character, the methods and the role of physical therapy in oncology, as an increasingly popular strategy in medicine, which helps to improve performance and physical function in cancer patients. Physical therapy is essential in primary and secondary cancer prevention and it greatly contributes to improving the quality of life of patients and helps them recover quicker. Four basic kinds of intervention in oncological rehabilitation include: preventive interventions, restorative interventions, supportive interventions and palliative interventions. The main principle in rehabilitating a patient with an advanced cancer is progressing steadily but gradually. The primary and essential form of rehabilitation for cancer patients is movement exercise i.e. kinesiotherapy. Integration and cooperation during group exercise are also among the strategies that therapists seek to employ while working to improve the condition of patients diagnosed with cancer. Kinesiotherapy prevents pulmonary and thromboembolic complications in cancer patients. One method of physical therapy applied in cancer treatment is lymphatic drainage (massage), which improves circulation of lymph. To sum up, physical therapy plays an increasingly important role in holistic care of cancer patients. It is indispensable and should become a standard approach, as a method of reducing the risk of complications, helping in faster recovery and limiting the economic and social costs of treatment.
4

Miejsce i rola promocji zdrowia w onkologii

86%
Rytwinski K.
Roczniki Państwowego Zakładu Higieny
|
1996
|
tom 47
|
nr 4
431-437
Przedyskutowano kierunki działania i dotychczasowe doświadczenia związane z promocją zdrowia w onkologii, ze szczególnym uwzględnieniem programów psychosocjalnego wsparcia. Wskazano na potrzebę zmodyfikowanych działań, które omówiono także w aspekcie zadań oświaty zdrowotnej.
5

Changes in mycoflora of man's respiratory system - observed during last some years - yeasts

86%
Dynowska M.
Acta Mycologica
|
1993
|
tom 28
|
nr 2
6

Molecular markers of apoptosis as prognostic indicators in cancer

86%
Walaszek Z., Hanausek M.
Cellular and Molecular Biology Letters
|
2000
|
tom 05
|
nr 2
7

Genetical control on Lentinan - induced acute phase responses and vascular responses

86%
Maeda Y. Y., Sakaizumi M., Moriwaki K., Chihara G., Yonekawa H.
Folia Histochemica et Cytobiologica
|
1992
|
tom 30
|
nr 4
8
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

Neoplastic lesions in slaughter animals in Warminsko-Mazurskie voivodship (Poland) area during the years 2001-2007

72%
Radkowski M., Siemionek J., Zdrodowska B.
Polish Journal of Veterinary Sciences
|
2010
|
tom 13
|
nr 4
During the period of 7 years, 2001-2007, 110,273 heads of cattle and 3,055,654 heads of pigs were examined by veterinarians of the Polish Veterinary Inspection in Warmińsko-Mazurskie voivodship. As a result of pre- and post-slaughter examination, 311 heads of cattle and 23 heads of pigs representing 0.279% and 0.00075% of the population respectively were considered unsuitable due to neoplastic lesions. The most frequently found lesions in cattle were fibroneuromas, neuromas and liposarcomas while in case of pigs those were various types of sarcomas, fibromas, cancers, nephromas and melanomas.
9
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

Analysis of changes in cancer health care system in Poland since the socio-economic transformation in 1989

72%
Dudek-Godeau D., Kieszkowska-Grudny A., Kwiatkowska K., Bogusz J., Wysocki M. J., Bielska-Lasota M.
Roczniki Państwowego Zakładu Higieny
|
2016
|
tom 67
|
nr 4
Background. The transformation period in Poland is associated with a set of factors seen as ‘socio-economic stress’, which unfavourably influenced cancer treatment and slowed down the progress of the Polish cancer care in the 90’s. These outcomes in many aspects of cancer care may be experienced till today. The results of the international EUROCARE and CONCORD studies based on European data prove evidence that there is a substantial potential for improvement of low 5-year survival rates in Poland. Since high survivals are related to notably efficient health care system, therefore, to improve organization and treatment methods seems to be one of the most important directions of change in the Polish health care system. Till today, cancer care in Poland is based on a network outlined by Professor Koszarowski in the middle of the last century, and is a solid foundation for the contemporary project of the Comprehensive Cancer Care Network (CCCN) proposed in the frame of CanCon Project. Objective. Analysis of the structure of health care system and the changes introduced within the network of oncology in Poland since the beginning of the post-commuinist socio-economic transformation in 1989. Materials and Methods. This study was conducted based on the CanCon methods aimed at reviewing specialist literature and collecting meaningful experiences of European countries in cancer care, including the main legal regulations. Results. The analysis provided evidence that the political situation and the economic crisis of the Transformation period disintegrated the cancer care and resulted in low 5-year survival rates. A step forward in increasing efficiency of the cancer treatment care was a proposal of the ’Quick Oncological Therapy’ together with one more attempt to organize a CCCN. With this paper the Authors contribute to the CanCon Project by exploration, analysis and discussion of the cancer network in Poland as an example of existing net-like structures in Europe as well as by preparation of guidelines for constructing a contemporary CCCN. Conclusions. (1) ‘Socio-economic’ stress adversely affected the efficiency of oncological treatment, both by reducing safety and slowing down the development of modern oncology. (2) Changing the current system into the contemporary form - CCCN could be an important step forward to optimise the oncological health care in Poland. (3) Introduction of the mandatory monitoring of organizational changes with the use of health standardized indicators could allow for the assessment of the effectiveness of implemented solutions and their impact on better prognosis for cancer patients. (4) Optimising the organization of the health care system is possible only by implementing necessary legislative corrections.
10
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

A role of ghrelin in cancerogenesis

72%
Majchrzak K., Szyszko K., Pawlowski K. M., Motyl T., Krol M.
Polish Journal of Veterinary Sciences
|
2012
|
tom 15
|
nr 1
Ghrelin is a 28 amino-acid multi-functional peptide hormone, which was identified as a natural ligand of the growth hormone secretagogue receptor (GHS-R). Pituitary growth hormone-releasing activity in both animals and humans has been well documented. It has various biological functions, including regulation of appetite and body weight, control of energy homeostasis, modulation of cardiovascular and gastrointestinal system and anti-inflammatory effect. However, both ghrelin and its receptor (GHS-R) are widely distributed in various tumors, which strongly implies their role in neoplastic cell growth trough autocrine/paracrine mechanism. Multiple studies have demonstrated the role of ghrelin in cancer cells proliferation, differentiation, invasiveness and apoptosis inhibition. The ghrelin axis is more complex than it was originally thought and consist of several compounds that might interact with each other and affect ghrelin activities. Here, we provide an overview of the ghrelin and its receptor role in tumor progression.
11

New argument in favour of orosomucoid [ OR ] microheterogeneity investigation in oncological practice

72%
Aleshkin V. A., Novikova L.
Folia Histochemica et Cytobiologica
|
1992
|
tom 30
|
nr 4
12

Tn antigens and their significance in oncology

72%
Lisowska E.
Acta Biochimica Polonica
|
1995
|
tom 42
|
nr 1
Tn and sialyl-Tn carbohydrate structures, first identified in glycophorins of persons with the rare Tn syndrome, were found to be present on the surface of most cancer cells. In this article, the studies on Tn and sialyl-Tn antigens as diagnostic and prognostic tumor markers and as immunogens in vaccines for cancer immunotherapy are shortly reviewed.
13

DNA and proteins of the nuclear matrix are the main targets of benzo[a]pyrene's action in rat hepatocytes

72%
Widlak P., Rzeszowska-Wolny J.
Acta Biochimica Polonica
|
1993
|
tom 40
|
nr 4
The binding of [14Clbenzo[a]pyrene (B[aJP) to DNA and proteins in total nuclei and subnuclear fractions of cultured rat hepatocytes was compared. The main targets of BlaJP were non-histone high molecular weight proteins of the nuclear matrix and DNA sequences attached to this structure. Following 24 h exposure to B[alP the amounts of adducts in the nuclear matrix DNA and proteins were twice as high as in total nuclei. After withdrawal of the carcinogen containing medium the level of B[a]P-induced adducts gradually decreased but always remained the highest in the nuclear matrix proteins. Removal of adducts from the nuclear matrix DNA was more efficient than from the other DNA fractions, and 72 h after exposure to the carcinogen the level of DNA adducts in this fraction was similar to that in total nuclei.
14

Postepy w skojarzonym leczeniu nowotworow

58%
Jassem J.
Acta Biologica et Medica
|
1992
|
tom 18
69-78
15
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

DNA microarrays - future in oncology research and therapy

58%
Krol M., Pawlowski K. M., Otrebska D., Motyl T.
Journal of Pre-Clinical and Clinical Research
|
2008
|
tom 02
|
nr 2
16

Zmiany ladunku elektrostatycznego a wzrost nowotworow

58%
Jaskowski J.
Acta Biologica et Medica
|
1992
|
tom 18
137-153
17

Why chemotherapy can fail?

58%
Krol M., Pawlowski K. M., Majchrzak K., Szyszko K., Motyl T.
Polish Journal of Veterinary Sciences
|
2010
|
tom 13
|
nr 2
18

Zastosowanie analizy cytogenetycznej w diagnostyce maziowczakow zlosliwych [synovioma malignum]

58%
Limon J., Mrozek K., Niedoszytko B., Kopacz A.
Acta Biologica et Medica
|
1992
|
tom 18
39-41
19

Makroczasteczki adhezyjne i ich rola w procesie nowotworowym

58%
Kozlowska K.
Acta Biologica et Medica
|
1992
|
tom 18
11-29
20

Chemioterapia dootrzewnowa w raku jajnika

58%
Emerich J., Dudziak M.
Acta Biologica et Medica
|
1992
|
tom 18
95-102
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