Wyniki wyszukiwania

1

Wplyw wielokrotnego podawania dimeru lizozymu na pierwotna odpowiedz humoralna myszy immunizowanych SRBC

100%

Obminska-Domoradzka B., Switala M., Debowy J.

Medycyna Weterynaryjna

|

1998

|

tom 54

|

nr 11

757-760

The study aimed at determining the effect of a multiple dose of lysozyme dimer (Lydium-KLP Nika Health Products) on primary humoral response in SRBC - immunized mice. The effects of a single (20 µg/kg) lysozyme dimer administered 2 h prior to antigen injection were compared with those of lysozyme dimer multiple doses (two-four) administered at one week intervals. The results of the study show that lysozyme dimer, irrespective of the number and range of the doses (2, 20 or 200 µg/kg) enhances humoral response to the antigen. The adjuvant action of lysozyme dimer is expressed in the increasing number of splenocytes producing hemolytic antibodies (PFC) and the total and 2-mercaptoethanol resistant level of anti-SRBC hemagglutinins. The strongest activation of the immune response was observed after a single administration and multiple injections at doses of 2 or 20 µg/kg. Three doses of lysozyme dimer (200 µg/kg each) injected at 7-day intervals decreased the number of PFC induced by this drug administered in a single dose of 20 µg/kg 2 h prior to immunization, but maintaining the potentializing impact on anti-SRBC antibody production. The results obtained in the study indicate that multiple doses of lysozyme dimer administered in doses recommended in veterinary practice (2-20 µg/kg), at 7-day intervals do not results in immunological tolerance.

2

Wplyw DTC i TFX na odpowiedz komorkowa i humoralna myszy poddanych stresowi unieruchomienia

86%

Obminska-Domoradzka B., Debowy J., Madej J. A.

Medycyna Weterynaryjna

|

1995

|

tom 51

|

nr 11

681-684

The experiments were carried out on mice (Balb/c, 6 weeks old) exposed to restraint stress. Animals were restrained for 12 h per day at nighttime and released at daytime for 2 consecutive days. Some mice were immunized i.p. immediately before the stress with 4xl08 sheep red blood cell (SRBC). Sodium diethyldithiocarbamate (DTC, 20 mg/kg) was administered i.p. twice e.g. 4 and 2 days prior to restraint stress. Calf thymus extract (TFX, 10 mg/kg) was injected i.p. four times at 24 h intervals prior to exposure to stress. It was found that restraint stress led to thymic atrophy which was reflected in the decreased total number of thymocytes, weight index of the thymus, and caused depletion of thymocytes. In addition, it was found that restraint stress reduced humoral response to SRBC which was reflected in the decreased number of splenocytes producing anti-SRBC antibodies (PFC) and serum haemagglutynin titres (19S+7S and 7S). The total number of spleen cells and weight index of the spleen in stressed mice were also diminished. The suppressing effect of stress was observed for 10 days. Pretreatment with DTC or TFX partially counteracted the immunosuppresive effects of restraint stress. Administration of DTC or TFX retarded the stress-induced thymic atrophy and promoted the restoration of the synthesis of anti-SRBC haemagglutinins and the number of PFC. Regeneration of the thymus gland occured more rapidly in stressed mice previously treated with TFX. On the other hand, the stronger effect of restoring the humoral response to SRBC was observed for DTC.

3

Mechanizmy immunologiczne u gadow

86%

Glinski Z., Buczek J.

Medycyna Weterynaryjna

|

1999

|

tom 55

|

nr 09

574-578

4

Test ELISA w ocenie odpowiedzi humoralnej na antygeny Microsporum canis u zwierzat

86%

Ziolkowska G., Wawrzkiewicz K., Sadzikowski Z.

Medycyna Weterynaryjna

|

1999

|

tom 55

|

nr 05

306-311

5

Badania immunologiczne w przebiegu eksperymentalnej inwazji Fasciola hepatica u szczurów

72%

Sadzikowski A.

Annales Universitatis Mariae Curie-Skłodowska. Sectio DD:Medicina Veterinaria

|

1984

|

tom 39

6

Porownanie wybranych parametrow odpornosci u lisow srebrzystych i polarnych

72%

Kostro K., Woloszyn S.

Medycyna Weterynaryjna

|

1996

|

tom 52

|

nr 04

255-257

The aim of the work was to compare selected nonspecific immunological parameters in silver and polar foxes. It was found that out of three mitogens (Con A, La and PWM) only Con A stimulated the strongest lymphocyte proliferation in both species of foxes. Mean stimulation indices and the absolute values of incorporated thymidine were significantly higher in polar foxes. The average percentages of phagocytes and the fatal indices of neutrophils were comparable in both species of foxes, while the mean value of the phagocyte index was much higher in the silver fox. However, in polar foxes a higher concentration of lysozyme in the blood serum was found. The differences in the parameters may influence the susceptibility of these foxes to some infections already at the level of nonspecific primary response.

7

Zaleznosc miedzy ekspozycja na kleszcze a intensywnoscia odpowiedzi immunologicznej przeciw Borrelia burgdorferi u ludzi

72%

Flisak R., Zalezny W., Prokopowicz D.

Medycyna Weterynaryjna

|

2000

|

tom 56

|

nr 09

579-581

8

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Strategie obrony przeciwzakaznej i sposoby ucieczki entomopatogenow spod kontroli immunologicznej owadow

72%

Jarosz J.

Wiadomości Parazytologiczne

|

1996

|

tom 42

|

nr 1

3-27

9

Immunosupresja u drobiu - próby przeciwdziałania jej skutkom lewamizolem. Cz.I. Badania eksperymentalne na kurczętach

72%

Rutherford M., Wisniewski J., Swiecicka-Grabowska G.

Zeszyty Naukowe. Przegląd Hodowlany

|

1998

|

tom 36

10

Wpływ meloksykamu na nieswoiste komórkowe i humoralne mechanizmy obronne u bydła w fazie lutealnej cyklu rujowego

72%

Markiewicz W., Wojcik R., Malaczewska J., Ziolkowski H., Jaroszewski J., Siwicki A. K.

Medycyna Weterynaryjna

|

2011

|

tom 67

|

nr 07

11

Odpowiedz humoralna i komorkowa w przebiegu doswiadczalnej fasciolozy u krolikow

72%

Sadzikowski A. B., Gundlach J. L.

Annales Universitatis Mariae Curie-Skłodowska. Sectio DD:Medicina Veterinaria

|

1994

|

tom 49

9-14

12

Odpowiedz humoralna organizmu zimujacych robotnic pszczoly miodnej Apis mellifera L. [Apidae]

72%

Pliszczynski M., Luft-Deptula D., Bizon K., Chelminski M.

Annales Universitatis Mariae Curie-Skłodowska. Sectio DD:Medicina Veterinaria

|

2006

|

tom 61

179-188

13

Kształtowanie się swoistej odpowiedzi humoralnej i komórkowej u gołębi immunizowanych atenuowaną i inaktywowaną szczepionką przeciwko salmonellozie

72%

Majer-Dziedzic B., Pochodyla M., Jaworska-Adamu J., Dudzic A., Tokarzewski S., Pochodyla A.

Medycyna Weterynaryjna

|

2015

|

tom 71

|

nr 04

The aim of the study was to observe the time course of the immune response in pigeons after immunization with a live (attenuated) vaccine, Zoosal T, and an autogenous bacterin (inactivated vaccine). The tube agglutination test and the ELISA test were used to measure the dynamics of serum antibodies to Salmonella, determine the white blood cell (WBC) count, and evaluate the leukogram of immunized pigeons. In order to evaluate the cellular response in immunized birds, a leukocyte migration inhibition (LMI) procedure was developed and tested. Histological changes were determined in pigeons immunized with ZOOSAL T and the experimental vaccine. The tests revealed a relationship between the beginning of the immune response as evaluated by tube agglutination and ELISA tests and by the MIF test. After immunization with ZOOSAL T, when the cellular response, as measured by the LMI test, appeared at day 14 and amounted to 32% migration inhibition, there was also a significant increase in antibody titers in the agglutination test (70.00) and an increase in ELISA OD values (0.259). After a single administration of the experimental vaccine, the agglutination antibody titers at day 21 of the experiment increased markedly (93.33), as did ELISA OD value, which increased until day 35 (to 0.345). Leukocyte migration inhibition reached the highest value (26%) at day 28, which shows that the immune response after single immunization increased more slowly than in group B. At day 7 after repeat vaccination with the autogenous bacterin, there was a significant increase in agglutination antibody titers (320.00). Similar patterns of changes were observed in the ELISA test. High OD values appeared at day 7 after revaccination (0.985) and persisted during the subsequent days of the experiment (28 days after revaccination: OD = 0.931) The cellular response appeared as early as 24 hours after revaccination (39% migration inhibition) and increased very rapidly, reaching 76% inhibition at day 3. Subsequently, there was a slow decline, but 2 weeks after repeat vaccination, the percentage of migration inhibition was still 22% (tab. 1, 2, 5). Our study demonstrated that the experimental vaccine based on an isolated strain of Salmonella Typhimurium var. Copenhagen, containing carbomer and Ginseng extract (Radix panax ginseg), administered twice to domestic pigeons induced a humoral and cellular immune response that was twice as strong as the response induced by the commercial vaccine ZOOSAL T.

14

Ksztaltowanie sie u zrebiat, w okresie od urodzenia do odsadzenia, poziomu swoistych przeciwcial IgM i IgG wobec wybranych bakterii srodowiskowych

72%

Wlodarczyk-Szydlowska A., Nowacki W., Florek M., Staroniewicz Z.

Medycyna Weterynaryjna

|

2006

|

tom 62

|

nr 04

455-458

The aim of the study was to investigate the level of IgM and IgG class antibodies, specific to selected pathogens in foals at particular stages during their nursing period. The tests were conducted in a thoroughbred stable. Twelve sera from mares and 12 sera from foals were examined and total protein and gamma globulin fraction levels were estimated as well as the relative level of specific antibodies in IgM and IgG class using the ELISA test and expressed as the value of optical density (OD) against the following strains of bacteria antigens: Staphylococcus sciuri (1), Staphylococcus sciuri (2), Staphylococcus sciuri (3), Staphylococcus xylosus (4), Staphylococcus xylosus (5), Staphylococcus aureus (6), Staphylococcus aureus (7), Streptococcus equi subsp. Zooepidemicus (8), Streptococcus equi subsp. Zooepidemicus (9), Enterobacter aglomerans (10), Rhodococcus equi (11), Salmonella enterica ser Typhimurium (12). Traces of specific Ig R. equi were indicated in the foals sera before suckling whereas the OD value increased to 0.35 in sera following the absorption of colostrum. The profile of specific humoral response against environmental pathogens in nursing foals is dependent not only on antigenic moiety of the pathogen but also on the immunological status of the individual.

15

Wplyw splenoktomii na przebieg odpowiedzi humoralnej i komorkowej oraz morfologie centralnych narzadow limfatycznych u kurczat immunizowanych roznymi antygenami

72%

Graczyk S., Madej J., Pliszczak-Krol A.

Zeszyty Naukowe Akademii Rolniczej we Wrocławiu. Weterynaria

|

1998

|

tom 58

7-15

16

Immunosupresja u drobiu - próby przeciwdziałania jej skutkom lewamizolem. Cz.II. Badania eksperymentalne na indykach

72%

Rutherford M., Wisniewski J., Swiecicka-Grabowska G.

Zeszyty Naukowe. Przegląd Hodowlany

|

1998

|

tom 36

17

Some humoral effects in Siberian sturgeon [Acipenser baeri Brandt] after lysozyme dimer application in bath

72%

Kolman H., Kolman R., Siwicki A. K., Szczepkowska B.

Archiwum Rybactwa Polskiego

|

2000

|

tom 08

|

nr 2

171-180

18

Wplyw Lydium KLP i LPS na regulacje temperatury oraz odpowiedz humoralna u krolikow

72%

Mukezamfura P., Fiolka M., Zieba P., Studzinski T.

Medycyna Weterynaryjna

|

1996

|

tom 52

|

nr 12

783-785

Lydium KLP (dimer lysozyme) used in veterinary practice as an immunostimulator has different effects of action on humoral immunity of rabbits compared with endotoxin (LPS) activity. E. coli endotoxin (Kroeger O8) given intravenously induced humoral immunity in rabbits after its first injection while the first administration of Lydium KLP hardly stimulated humoral immunity in comparison to the second dose. LPS is commonly regarded as a pirogen while Lydium KLP is not. The results obtained indicate different effects of Lydium KLP and LPS on antibody production and on temperature release.

19

Patogeneza pryszczycy

72%

Paprocka G.

Medycyna Weterynaryjna

|

2008

|

tom 64

|

nr 10

1180-1183

Foot-and-mouth disease (FMD) is a highly contagious viral vesicular disease of cloven-hoofed animals of the Artiodactyla order. The disease is characterized by fever, lameness and vesicular lesions on the tongue, feet, snout and teats. It is generally accepted that primary infection of ruminants usually occurs by the respiratory route, whereas pigs are usually infected by the oral route. Pigs are much less susceptible to aerosol infection than cattle, yet they excrete far more aerosolized virus than cattle or sheep. In addition, cattle, sheep, and goats can become carriers. The virus elicits a rapid humoral response in either infected or vaccinated animals Virus-specific antibodies protect animals in a serotype-specific manner against reinfection, or against infection in the case of vaccination. Protection is correlated with a high levels of neutralizing antibodies. The role of cellular immunity in the protection of animals from FMD is still a matter of some controversy.

20

Odpornosc przeciw zakazeniu wirusem influenzy koni

72%

Purzycka M., Rozek W., Zmudzinski J. F.

Medycyna Weterynaryjna

|

2007

|

tom 63

|

nr 12

1519-1521

Influenza virus plays an important role in respiratory diseases in horses. Equine influenza virus is represented by two different serotypes: H7N7 and H3N8. The strain H7N7 has not been isolated since 1980 and H3N8 circulates in the equine population throughout most of the world. For preventive and prophylactic measures inactivated and subunit vaccines are most commonly used. Contrary to natural infections, traditional vaccines induce neither cytotoxic lymphocytes T nor mucosal antibodies and they do not provide enduring immunity. There is also the difference in the immune response as the natural infection induces IgA, IgGa and IgGb antibodies whereas the traditional vaccines induce IgGc and IgG(T) and no IgA. The low efficacy of the traditional vaccines also depends on an antigenic drift of the surface glycoprotein - hemagglutynin.

Ograniczanie wyników

Wplyw wielokrotnego podawania dimeru lizozymu na pierwotna odpowiedz humoralna myszy immunizowanych SRBC

Wplyw DTC i TFX na odpowiedz komorkowa i humoralna myszy poddanych stresowi unieruchomienia

Mechanizmy immunologiczne u gadow

Test ELISA w ocenie odpowiedzi humoralnej na antygeny Microsporum canis u zwierzat

Badania immunologiczne w przebiegu eksperymentalnej inwazji Fasciola hepatica u szczurów

Porownanie wybranych parametrow odpornosci u lisow srebrzystych i polarnych

Zaleznosc miedzy ekspozycja na kleszcze a intensywnoscia odpowiedzi immunologicznej przeciw Borrelia burgdorferi u ludzi

Strategie obrony przeciwzakaznej i sposoby ucieczki entomopatogenow spod kontroli immunologicznej owadow

Immunosupresja u drobiu - próby przeciwdziałania jej skutkom lewamizolem. Cz.I. Badania eksperymentalne na kurczętach

Wpływ meloksykamu na nieswoiste komórkowe i humoralne mechanizmy obronne u bydła w fazie lutealnej cyklu rujowego

Odpowiedz humoralna i komorkowa w przebiegu doswiadczalnej fasciolozy u krolikow

Odpowiedz humoralna organizmu zimujacych robotnic pszczoly miodnej Apis mellifera L. [Apidae]

Kształtowanie się swoistej odpowiedzi humoralnej i komórkowej u gołębi immunizowanych atenuowaną i inaktywowaną szczepionką przeciwko salmonellozie

Ksztaltowanie sie u zrebiat, w okresie od urodzenia do odsadzenia, poziomu swoistych przeciwcial IgM i IgG wobec wybranych bakterii srodowiskowych

Wplyw splenoktomii na przebieg odpowiedzi humoralnej i komorkowej oraz morfologie centralnych narzadow limfatycznych u kurczat immunizowanych roznymi antygenami

Immunosupresja u drobiu - próby przeciwdziałania jej skutkom lewamizolem. Cz.II. Badania eksperymentalne na indykach

Some humoral effects in Siberian sturgeon [Acipenser baeri Brandt] after lysozyme dimer application in bath

Wplyw Lydium KLP i LPS na regulacje temperatury oraz odpowiedz humoralna u krolikow

Patogeneza pryszczycy

Odpornosc przeciw zakazeniu wirusem influenzy koni