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1

Wpływ efektywnych mikroorganizmów na nieswoistą odporność komórkową u sandacza

100%
Terech-Majewska E., Kaczorek E., Schulz P., Zakes Z., Rozynski M., Kowalska A., Zembrzuska M., Siwicki A. K.
Medycyna Weterynaryjna
|
2018
|
tom 74
|
nr 05
Effective Microorganisms (EM) technology uses microorganisms to work in the surrounding environment. Complex microbiological preparations show synergistic effects, combining the effects of probiotics, prebiotics and synbiotics. EMTM technology is well-known and used in 120 countries worldwide, mainly in agriculture, including aquaculture, and in environmental protection. Fish farmers use these preparations to enhance fish growth, condition and immunity. The aim of the study was to evaluate the effect of EM-Probiotic (Greenland) on the development of cellular non-specific resistance in pikeperch (Sander lucioperca) at the initial stage of rearing in a recirculating aquaculture system (RAS). The experimental diet was administered for 28 days with EM supplementation at 0% (control group), 2% and 4% of the feed. Water temperature in the RAS was maintained at 22.0ºC. Hematopoietic organs (spleen and kidney) were collected twice, after 28 days of EM supplementation (first term) and 28 days after cessation of supplementation (second term). The respiratory burst activity (RBA) and potential killing activity (PKA) of macrophages, as well as the proliferative activity of T- and B-lymphocytes (MTT assay) were assessed. The results of the study show that EM at the initial stage of pikeperch development (body weight of 2 to 14 g) suppress cellular defence mechanisms, decreasing the activity of immunocompetent cells in RBA, PKA and MTT tests. The results from the first organ harvesting showed differentiated EM activity at a statistically insignificant level (P > 0.05). In samples collected 28 days later, the inhibitory effect was demonstrated at a statistically significant level (P < 0.05) in all parameters in both experimental groups. Non-specific cellular immunity in fish plays a key role in defence against damaging factors, including pathogenic ones. Since fish in an RAS are also susceptible to potentially pathogenic agents, immunosuppression of these mechanisms may aggravate the disease.
2

Wplyw Lydium-KLP na wybrane wskazniki nieswoistej odpornosci komorkowej u zdrowych psow

100%
Kiczka W., Pomorski W., Taszkun I., Milczak A., Sitkowski W.
Życie Weterynaryjne
|
1994
|
tom 69
|
nr 04a
145-148
3

Wplyw beta-1,3-1,6-D-glukanu na nieswoiste komorkowe mechanizmy obronne jagniat

100%
Wojcik R., Malaczewska J., Trapkowska S., Siwicki A. K.
Medycyna Weterynaryjna
|
2007
|
tom 63
|
nr 01
84-86
The aim of the study was to estimate the influence of β-1,3/1,6-D-glucan applied in feed on non-specific cellular immunity in lambs. The study examined twenty six 21-28 day old lambs in two groups: I - control and II - experimental (7 rams and 6 ewes in each group). The animals were kept under identical zoohygienic and nutritional conditions. Lambs from group I were fed a basal control diet and lambs from group II were fed a diet containing β-1,3/1,6-D-glucan, at doses of 80 mg/kg/day. Blood was taken from the control and experimental groups before the lambs were fed a diet containing β-1,3/1,6-D-glucan, and 15, 30 and 60 days after administration of the diet. The respiratory burst activity (RBA) and potential killing activity (PKA) of blood phagocytes and proliferative response of blood lymphocytes (MTT) stimulated by mitogens concanavalin A (ConA) and lipopolisaccharide (LPS) were examined. The results indicated that when β-1,3/1,6-D-glucan was applied to food it statistically significantly increased the blood phagocyte and lymphocyte activity in the lambs until the end of experiment, compared to the control group.
4

Przewlekla pneumopatia obturacyjna u koni [COPD]. Cz.II. Badania nad uwarunkowaniami immunologicznymi przewleklego obturacyjnego schorzenia drog oddechowych [COPD] u koni

84%
Taszkun I., Pomorski Z., Dutkiewicz J., Milczak A.
Magazyn Weterynaryjny
|
1997
|
tom 06
|
nr 4
264-267
5

Wplyw meloksykamu na nieswoiste komorkowe i humoralne mechanizmy obronne u bydla

84%
Wojcik R., Markiewicz W., Malaczewska J., Chrostowska M., Maslanka T., Rotkiewicz Z., Jaroszewski J., Siwicki A. K.
Medycyna Weterynaryjna
|
2006
|
tom 62
|
nr 12
1400-1402
The aim of the study was to determine the influence of meloxicam a nonsteroid anti-inflammatory drug, on nonspecific cellular and humoral defense mechanisms in cows. Ten heifers in two groups (experimental and control) were examined. Meloxicam was given once only to the experimental group during the course of the study. The levels of lysozyme activity and total protein as well as ceruloplasmine, gamma globulin and metabolic activity (RB A), the killing activity of macrophages (PKA) and proliferate response of lymphocyte were measured in the blood. The results indicate the immunosuppressive effect of Meloxicam on nonspecific cellular and humoral responses which, in practice, could appear as an increased sensitivity to infection, a decrease in post-vaccine immunity as well as the occurrence of various asymptomatic infections.
6

Podstawy immunologii, czyli co lekarz powinien wiedzieć

84%
Pomorska-Mol M.
Weterynaria w Terenie
|
2011
|
tom [05] Monografia. Choroby świń i Bydła
7

Staphylococcus aureus kontra uklad immunologiczny

84%
Fijalkowski K., Czernomysy-Furowicz D., Ferlas M.
Postępy Mikrobiologii
|
2008
|
tom 47
|
nr 4
497-501
8

Wybrane dane z zakresu immunologii psow i kotow

84%
Deptula W., Tokarz-Deptula B.
Magazyn Weterynaryjny
|
2003
|
tom 12
|
nr 05
21-24
9

Ksztaltowanie sie wybranych wskaznikow nieswoistej odpornosci komorkowej i humoralnej w przebiegu cyklu rujowego u jalowek

84%
Krakowski L., Krzyzanowski J., Wrona Z.
Annales Universitatis Mariae Curie-Skłodowska. Sectio DD:Medicina Veterinaria
|
1998
|
tom 53
217-221
10

Cytometryczna ocena aktywnosci fagocytarnej i metabolizmu tlenowego granulocytow krwi obwodowej krolikow z przewlekla trichofitoza

84%
Kostro K., Wojcicka-Lorenowicz K., Lesniewska K., Madany J., Majer-Dziedzic B.
Medycyna Weterynaryjna
|
2006
|
tom 62
|
nr 04
423-426
The aim of the study was to evaluate the activity of peripheral blood granulocytes in rabbits with chronic trichophytosis by using commercial sets of Phagotest and Burstest adopted to flow cytometry. A strong suppression of unspecific cellular immune responses was found in rabbits with chronic trichophytosis. Once fungal infection is established it can only be destroyed by T cell-mediated mechanisms. T cells primarily function by activating macrophages and by promoting epidermal growth and keratinization. The destroyed unspecific immune mechanisms are manifested by decreased phagocyte activity and oxygen metabolism of granulocytes. Therefore, it is reasonable to assume that when vaccine therapy is used to treat chronic trichophytosis in rabbits with unspecific immunity it should be modulated in order to restore the destroyed mechanisms of unspecific immunity. The latter's normal functioning is a prerequisite for the development of specific antifungal immunity.
11

Komorkowa odpornosc nieswoista u lisow hodowlanych w zaleznosci od zachowan behawioralnych

84%
Kostro K., Zon A., Bielanski P., Jarosz L.
Medycyna Weterynaryjna
|
2007
|
tom 63
|
nr 03
322-325
The objective of the studies was the comparison of chosen unspecific immune cellular parameters in female polar foxes of different behavioral types in the preparturient period. The studies were conducted on 51 female foxes of the basal breed divided into three groups: confident, timid and aggressive animals. The animals were divided on the basis of behavior in the catching and feeding tests. Statistically significant differences were found in the examined parameters of unspecific cellular immune responses in relation to the behavioral type. The highest values of the NBT reduction, phagocytic and bactericidal activity was noted in the confident male foxes and the lowest one in the timid animals. The observed differences in unspecific cellular immune parameters in breeding foxes of different behavior related to the genome may influence the susceptibility of animals to infectious diseases. In selection irrespectively of breeding parameters studies on immunity should be kept in mind.
12

Wplyw podawania izoprynozyny i Mycobacterium chelonae na wybrane wskazniki nieswoistej odpornosci komorkowej i humoralnej u koni

84%
Krzyzanowski J., Krakowski L., Siwicki A. K.
Annales Universitatis Mariae Curie-Skłodowska. Sectio DD:Medicina Veterinaria
|
1997
|
tom 52
261-269
13

The effect of natural immunomodulators applied in immersion on non-specific immune responses in Russian sturgeon [Acipenser gueldenstaedti Brandt]

67%
Kolman H., Siwicki A. K., Kolman R.
Archiwum Rybactwa Polskiego
|
1998
|
tom 06
|
nr 2
391-410
14

Nieswoista i swoista odpornosc komorkowa u buhajow zakazonych naturalnie wirusem IBR-IPV [Bovid herpes virus 1-BHV1]

67%
Deptula W.
Medycyna Weterynaryjna
|
1992
|
tom 48
|
nr 06
276-279
The observations were done on 10 bulls at the age of 3—4 years in two experimental groups. Group A — 5 bulls with the coital exanthema and group В — 5 healthy bulls. Clinical, bacteriological, virological (serology, immunofluorescence, cultivation) and immunological examinations were performed on days 1, 14, 28, 58 and 84. Serological examinations included a spontaneous and stimulated leukocyte migration and PMN’s migration, number of PMN’s, phagocytic activity of PMN, the NBT and the test of intracellular killing. Moreover, there was examined a specific cellular immunity by the skin test (DTH) against a specific antigen, by migration inhibition test of leukocytes (LIMF) and granulocytes (LIF). The presence of specific antibodies against PI-3, BHV-1, VDMD, RSV, adeno-2 and 5, BLV was determined by HI, SN, CF, immunodiffusion and ELISA. Moreover culture studies and the direct immunofluorescence test were used to detect BHV-1. Cultural studies to detect aerobic and anaerobic bacteria, mycoplasms, ureaplasms and sero-cultural studies to exclude chlamydial infections were performed. In bulls with the coital exanthema desides changes in reactivity of lymphocytes В and T a profoud changes concerned also the phagocytic activity of PMN’s and/or leukocytes confirming the role of unspecific cellular immunity in bulls with coital exanthema.
15

Zakaźna martwica układu krwiotwórczego ryb łososiowatych (IHN): aktualny stan wiedzy oraz wpływ wirusa IHN na układ odpornościowy

67%
Siwicki A. K., Terech-Majewska E.
Komunikaty Rybackie
|
2011
|
nr 6
The IHN virus induces high mortality among fishes, especial rainbow trout fingerlings. This study focuses on the in vitro influence of IHN virus on spleen phagocyte activity and the proliferative response of pronephros lymphocytes stimulated by mitogens ConA and LPS. The results indicate that the IHN virus decreased the metabolic activity (RBA) and potential killing activity (PKA) of spleen phagocytes statistically significantly (P<0.05). A similar pattern was observed in lymphocyte activity, with the IHN virus statistically significantly (P<0.05) decreasing the proliferative response of pronephros lymphocytes stimulated by mitogens ConA and LPS. The results of this study showed that IHN virus suppressed cell-mediated immunity in rainbow trout.
16

Immunostymulujacy wplyw glukanu 1,3-1,6 oraz lewamizolu na komorkowe i humoralne mechanizmy obronne u koni

67%
Krzyzanowski J., Krakowski L., Branecka K., Siwicki A. K.
Annales Universitatis Mariae Curie-Skłodowska. Sectio DD:Medicina Veterinaria
|
1996
|
tom 51
133-142
17

Wplyw glukanu 1,3-1,6-beta-D [Leiber-Beta S, Niemcy] na nieswoiste mechanizmy obronne u siei [Coregonus lavaretus L.] w intensywnych systemach chowu

67%
Szczepkowska B., Siwicki A. K., Szczepkowski M., Glabski E., Kazun B., Kazun K., Terech-Majewska E., Majewicz-Zbikowska E.
Komunikaty Rybackie
|
2009
|
nr 6
2-5
The aim of the study was to determine the impact of different doses of 1,3-1,6-β-D glucan (Leiber-Beta S, Germany) on the results of rearing and the non-specific cellular and humoral defense mechanisms in whitefish reared in a closed system. The study material comprised fry with a mean body weight of 21.2 g and a mean body length of 12.4 cm. The experiment was 129 days long. Three feeding treatments were applied: control group (K) - standard feed without the addition of glucan; group G-200 with the addition of Leiber-Beta S glucan at a dose of 200 g per ton of feed; group G-500 with the addition of Leiber-Beta S glucan at a dose of 500 g per ton of feed. No significant differences were noted among the treatment groups with regard to growth or feed conversion ratio. In comparison to the control group, statistically significant increases in macrophage phagocytic activity and in T and B lymphocyte proliferation were noted in the fish fed dietary treatments with the addition of glucan. Simultaneously, statistically significant increases in lyzozyme activity and in serum Ig levels were noted in comparison with those in the control groups. However, no significant differences were noted between the doses of 200 and 500 g of glucan per ton of feed. The results of this study indicate that the application of Leiber-Beta S glucan stimulates the non-specific defense mechanisms in whitefish at doses of 200 and 500 g per ton of feed.
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