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Next-generation nutraceuticals: bioactive peptides from plant proteases

100%

Matkawala F., Nighojkar S., Nighojkar A.

BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology

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2022

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tom 103

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nr 4

2

BonisteinTM (synthetic genistein), a food component in development for a bone health nutraceutical

84%

Ullmann U., Bendik I., Fluhmann B.

Journal of Physiology and Pharmacology. Supplement

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2005

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tom 56

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nr 1

79-95

In the discussion of the risk-benefit relation of the hormone replacement therapy (HRT) for elder women phytochemicals with estrogenic activity received a great deal of attention. Phytoestrogens are naturally occurring compounds with structural similarity to 17b-estradiol. Especially genistein, an isoflavone most abundant in soy, possess a high and selective binding-affinity to the mammalian estrogen receptors. It has been found, that genistein exert in humans both: weak estrogenic and antiestrogenic effects, similar to the SERMs. Consequently, it was concluded, that genistein might provide an alternative to prevent postmenomausal bone-loss and ameliorate menopausal symptoms without side-effects similar to HRT. Pre-clinical experiments and results from clinical pilot studies with pure genistein confirmed its efficacy in these indications. Nevertheless, currently some open issues still exist to recommend its intake thoughtlessly. Bonistein, pure synthetic genistein developed by DSM Nutritional Products, was tested extensively in appropriate models for bone health. A battery of toxicological studies was conducted to determine safe intake levels. In the early clinical development pharmacokinetic studies were performed in healthy volunteers and in postmenopausal women. Now large-scale studies are in preparation to investigate Bonistein's efficacy in postmenopausal bone-loss and climacteric syndrome.

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The application of in vitro and in vivo transgenic approaches for evaluating the harmful or beneficial effects of foods

84%

Wolf C. R., Henderson C., Scheer N.

Polish Journal of Food and Nutrition Sciences

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2011

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tom 61

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nr Suppl.1

4

North American wild rice - rich source of nutraceuticals

84%

Klensporf-Pawlik D., Rudzinska M., Przybylski R.

Polish Journal of Food and Nutrition Sciences

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2011

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tom 61

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nr Suppl.1

5

Nutraceuticals as anti-angiogenic agents: hopes and reality

84%

Dulak J.

Journal of Physiology and Pharmacology. Supplement

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2005

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tom 56

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nr 1

51-69

Angiogenesis, the formation of new blood vessels from preexisting vascular network is a driving force of organ development in ontogeny, is necessary for ovulation and hair growth, and is prerequisite for proper wound healing. It is also a critical mechanism of numerous diseases, the most important of which are cancer and atherosclerosis. Therefore, modulation of angiogenesis is considered as therapeutic strategies of great importance for human health. Numerous bioactive plant compounds, often referred to as nutraceuticals are recently tested for the potential clinical applications. Among the most frequently studied are resveratrol, a polyphenol present in red-wine and grape-seed, epigallocatechin-3- gallate (EGCG) from green tea and curcumin from Curcuma longa. It is also possible that components of other plants, including the constituents of local food diet may find application for modulation of angiogenesis, provided that their effectiveness will be confirmed in controlled, scientifically validated trials.

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"Local food - nutraceuticals": An example of a multidisciplinary research project on local knowledge

84%

Heinrich M., Leonti M., Nebel S., Peschel W.

Journal of Physiology and Pharmacology. Supplement

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2005

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tom 56

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nr 1

5-22

Currently, dietary patterns change rapidly all over the world. Most notably, there is a fast increase in the convenience food market. Here we discuss the overall theoretical framework and strategy of an EU-funded project on local food, a common resource in many parts of the Mediterranean. Such food is often only available seasonally and is consumed either fresh (e.g. spring salads and vegetables, fruits in autumn) or in a conserved form (dried, fermented, pickled). There is an urgent need to document and analyse such local resources, which are today at the brink of disappearance. In this project, selected species were studied using a multidisciplinary approach, including strategies and methods from pharmacology, nutritional sciences and anthropology (i.e. ethnopharmacological or ethnonutritional ones). For example, all extracts were profiled using HPLC-MS, by determining their polyphenol content and using a variety of in vitro anti-oxidant assays (incl. guaiacol oxidation, xanthine oxidase inhibition, HOCl scavenging, eNOS activity). Such research also points to ways for ascertaining the intergenerational transmission of the knowledge and for sustainable development and management. Examples from field studies in southern Italy and from pharmacological studies using a variety of targets are used to illustrate the potential of such neglected resources. The wider implications of such an approach, for example, for the study of similar traditions in Central and Eastern Europe are also discussed.

7

Herbs in animal feeding

84%

Grela E. R., Kowalczuk E.

Herba Polonica

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2007

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tom 53

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nr 3

The problem of possible utilization of herbs or their extracts in the animal diets was studied. The future of using herbs in animal feeding will in great measure depend on the knowledge of chemical structure, their value and characteristics of particular herbs or their extracts, physiological needs and well-being of animals, and, above all, on consumers' preferences and expectations.

8

Jak zostac liderem funkcjonalnosci?

67%

Bogacz A.

Przemysł Fermentacyjny i Owocowo-Warzywny

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2007

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tom 51

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nr 07-08

8

9

Halomonas sp. nov., an EPA-producing mesophilic marine isolate from the Indian Ocean

67%

Salunkhe D., Tiwari N., Walujkar S., Bhadekar R.

Polish Journal of Microbiology

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2011

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tom 60

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nr 1

Marine samples from the Indian Ocean were used to isolate and characterize the organisms with respect to their fatty acid profiles. Six mesophilic isolates (MBRI 6, MBRI 8, MBRI 9, MBRI 10, MBRI 12 and MBRI 13) were obtained from three different water samples. They were i) Gram-negative, ii) catalase positive, iii) produced acid from glucose and maltose, iv) tolerated 5 to 15% NaCl v) except MBRI 9, showed pH tolerance in the range of 5.0 to 9.0 with optimum pH 7.0 to 8.0 v) grew well at 30°C and were able to grow in the range of 15 to 45°C. EPA, an essential omega-3 fatty acid, was produced by these isolates in the range of 12 to 60% at 30°C. MBRI 12 was found to be a potential source as it produced 60% EPA. This isolate was further identified by partial 16S rDNA sequencing and phylogenetic analysis revealed that the strain belonged to Gammaproteobacteria and was closely related to Halomonas bolviensis (96% sequence similarity, 570 bp). Thus a new genus of Halomonas may be included in earlier reported EPA- producing prokaryotic genera affiliated to the Gammaproteobacteria.

10

Eggs as a main source of new generation of nutraceuticals

67%

Trziszka T.

Polish Journal of Food and Nutrition Sciences

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2011

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tom 61

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nr Suppl.1

11

Zywnosc funkcjonalna i nutraceutyki

67%

Stanczak A., Ochocki Z.

Bromatologia i Chemia Toksykologiczna

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2003

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tom 36

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nr 3

181-191

12

Cereal based functional foods and nutraceuticals

67%

Otles S., Cagindi O.

Acta Scientiarum Polonorum. Technologia Alimentaria

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2006

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tom 05

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nr 1

Wheat, buckwheat, oat, barley, flaxseed, psyllium, brown rice, soy and products are notified the most common cereal based functional foods and nutraceuticals. In this paper, these cereals and their beneficial effects to improve the health, to prevent and reduce the risk factors for several diseases are reviewed.

13

Żywność - po pierwsze nie szkodzić (artykuł przeglądowy)

59%

Chmielewska M., Tys J., Petkowicz J., Petkowicz B.

Acta Agrophysica

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2018

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tom 25

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nr 1

Artykuł dotyczy zagadnień wpływu żywności na zdrowie człowieka. W pracy omówiono skład chemiczny, proporcje aminokwasów, kwasów tłuszczowych, sacharydów zawartych w produktach, które spożywamy i ich wpływ na jakość i bezpieczeństwo żywności. Przedstawiono także funkcje i kryteria, jakie powinna spełniać żywność oraz, w jakich warunkach powinna być wyprodukowana, aby jej spożywanie było jak najmniej szkodliwe dla organizmu. W pracy dokonano także podziału żywności wg obowiązujących definicji żywności funkcjonalnej i nutraceutyku. Na podstawie przeglądu literatury wykazano, jaki skład chemiczny żywności jest szczególnie niebezpieczny dla chorób układu krążenia oraz chorób nowotworowych. W artykule omówiono rolę kwasów tłuszczowych i ich wpływ na rozwój różnego rodzaju chorób. Przedstawiono także badania oleju „Kropla Zdrowia” przeprowadzonych w Instytucie Agrofizyki w aspekcie medycznym.

14

Trendy na swiatowym rynku aromatow i dodatkow do zywnosci w 2007 r.

51%

Bogacz A.

Przemysł Fermentacyjny i Owocowo-Warzywny

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2007

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tom 51

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nr 07-08

12

15

DSM Nutritional products. Witaminy, karotenoidy, nutraceutyki i inne specjalistyczne dodatki do zywnosci

51%

Przemysł Fermentacyjny i Owocowo-Warzywny

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2007

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tom 51

|

nr 07-08

20

16

Nutraceutyki, zywnosc funkcjonalna - rola i bezpieczenstwo stosowania

51%

Oledzka R.

Bromatologia i Chemia Toksykologiczna

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2007

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tom 40

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nr 1

1-8

Ograniczanie wyników

Next-generation nutraceuticals: bioactive peptides from plant proteases

BonisteinTM (synthetic genistein), a food component in development for a bone health nutraceutical

The application of in vitro and in vivo transgenic approaches for evaluating the harmful or beneficial effects of foods

North American wild rice - rich source of nutraceuticals

Nutraceuticals as anti-angiogenic agents: hopes and reality

"Local food - nutraceuticals": An example of a multidisciplinary research project on local knowledge

Herbs in animal feeding

Jak zostac liderem funkcjonalnosci?

Halomonas sp. nov., an EPA-producing mesophilic marine isolate from the Indian Ocean

Eggs as a main source of new generation of nutraceuticals

Zywnosc funkcjonalna i nutraceutyki

Cereal based functional foods and nutraceuticals

Żywność - po pierwsze nie szkodzić (artykuł przeglądowy)

Trendy na swiatowym rynku aromatow i dodatkow do zywnosci w 2007 r.

DSM Nutritional products. Witaminy, karotenoidy, nutraceutyki i inne specjalistyczne dodatki do zywnosci

Nutraceutyki, zywnosc funkcjonalna - rola i bezpieczenstwo stosowania