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Nonhistone chromosomal proteins [NHCP] in adenocarcinoma of human endometrium

100%

Miturski R.

Acta Biochimica Polonica

1995

tom 42

nr 2

Concentration and electrophoretic pattern of nonhistone chromosomal proteins (NHCP) in cancer and normal endometrium were examined. In normal tissues the NHCP/DNA ratio ranged from 0.6 to 0.8 whereas in malignant tissues from 1.2 to 1.7. Mean nuclear concentration of NHCP was 14.16 pg/cell nucleus of normal endometrium and 33.35 pg/cell nucleus of cancer tissue. The two tissues differed in the electrophoretic pattern. Heavy fractions (>60 kDa — 36%) predominated in normal tissue whereas light fractions (< 30 kDa — 48%) in malignant tissue samples. The percentage of intermediate fractions (30-60 kDa) was similar. Neoplastic endometrium shows, irrespective of the patient's age, a high NHCP content. It seems that NHCP, especially the fraction extracted with 0.35 M NaCl, because of its tissue and cell specificity are involved in neoplasm formation.

Transcriptional activity of a complex of wheat RNA polymerase II and nonhistone chromosomal protein (NHCP)

84%

Dullin P., Galbas M., Chodynicka-Kordus G., Fabisz-Kijowska A., Walerych W.

Acta Biochimica Polonica

1989

tom 36

nr 3-4

Ograniczanie wyników

2 Acta Biochimica Polonica

1 Chodynicka-Kordus G.

1 Dullin P.

1 Fabisz-Kijowska A.

1 Galbas M.

1 Miturski R.

1 Walerych W.

1 1995

1 1989

Wyniki wyszukiwania

Nonhistone chromosomal proteins [NHCP] in adenocarcinoma of human endometrium

Transcriptional activity of a complex of wheat RNA polymerase II and nonhistone chromosomal protein (NHCP)