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The actions that can mitigate the adverse effects of various energy crises are continuous improvements in the efficiency of power generation plants. This can be achieved by carrying out the processes at an always higher temperature and pressure, and in a more aggressive environment than the parameters used so far. Such requirements cannot be satisfied any longer by the iron-based alloys, even the best ones. Therefore, multi-component alloys based on nickel and cobalt start to be the materials of choice. On the other hand, new materials of higher performance life are searched for all the time. Jointly with its American partners, the Foundry Research Institute in Krakow carries out the research works which, among others, aim at the conversion of both material and techno-logy from structures forged and welded in nickel superalloys to cast elements for operation under the most demanding conditions of the power plants of a new generation. A part of the research is done under an “A-USC - NICKEL” American programme, to participation in which the Foundry Research Institute has been invited. Within this programme, the initial studies have already been carried out to master the technique of melting and casting the Inconel 740 alloy and preliminary material testing has been performed on the ready castings. It has been stated, among others, that with the temperature increase, particularly above 700°C, this alloy when used as a cast material is characterised by a definitely less drastic decrease of tensile strength than the same alloy subject to plastic forming.
The increasing antibiotic resistance of pathogenic bacteria calls for the development of alternative antimicrobial strategies. Possible approaches include the development of novel, broad-spectrum antibiotics as well as specific targeting of individual bacterial virulence factors. It is impossible to decide currently which strategy will prove more successful in the future since they both promise different advantages, but also introduce diverse problems. Considering both approaches, our laboratory's research focuses on the evaluation of hemocidins, broad-spectrum antibacterial peptides derived from hemoglobin and myoglobin, and staphostatins, specific inhibitors of staphopains - Staphylococcus aureus secreted proteases that are virulence factors regarded as possible targets for therapy. The article summarizes recent advances in both fields of study and presents perspectives for further development and possible applications.
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