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The relation of transcription to memory formation

100%

Korzus E.

Acta Biochimica Polonica

2003

tom 50

nr 3

A distinction between short-term memories lasting minutes to hours and long-term memories lasting for many days is that the formation of long-term memories requires new gene expression. In this review, the focus is on the current understanding of the relation of transcription to memory consolidation based on the data collected from behavioral studies performed primarily on genetically altered animals. Studies in Drosophila and Aplysia indicate that the transcription factor cAMP/Ca2+ response element binding protein (CREB) is critical in mediating the conversion from short- to long-term memory. More recent genetic studies in mice also demonstrated CREB and inducible transcription factor Zif268 involvement in information storage processes. Transcription seems to play essential role in memory formation but the mechanisms for activation of transcription and downstream processes during memory consolidation remain unclear.

Characterization of new genes expressed during cucumber somatic embryogenesis

100%

Wisniewska A., Filipecki M., Pietraszewska A., Malepszy S.

Polish Journal of Natural Sciences. Supplement

2003

tom 01

Molecular cloning and expression analysis of a new gene for short-chain dehydrogenase-reductase 9

51%

Liu S., Huang C., Li D., Ren W., Zhang H., Qi M., Li X., Yu L.

Acta Biochimica Polonica

2007

tom 54

nr 1

We report here the cloning and characterization of a novel human short-chain dehydrogenases/ reductase gene SCDR9, isolated from a human liver cDNA library, and mapped to 4q22.1 by browsing the UCSC genomic database. SCDR9 containing an ORF with a length of 900 bp, encoding a protein with a signal peptide sequence and an adh_short domain. GFP localization shows SCDR9 protein concentrated in some site of the cytoplasm, but not in the ER. Expression pattern in eighteen tissues revealed that SCDR9 is expressed highly in liver. Soluble recombinant protein was successfully purified from Escherichia coli using pET28A(+) expression vector. Our data provides important information for further study of the function of the SCDR9 gene and its products.

Ograniczanie wyników

2 Acta Biochimica Polonica

1 Polish Journal of Natural Sciences. Supplement

1 Filipecki M.

1 Huang C.

1 Korzus E.

1 Li D.

1 Li X.

1 Liu S.

1 Malepszy S.

1 Pietraszewska A.

1 Qi M.

1 Ren W.

1 Wisniewska A.

1 Yu L.

1 Zhang H.

1 2007

2 2003

Wyniki wyszukiwania

The relation of transcription to memory formation

Characterization of new genes expressed during cucumber somatic embryogenesis

Molecular cloning and expression analysis of a new gene for short-chain dehydrogenase-reductase 9