Preferencje help
Polish version English version Język
Widoczny [Schowaj] Abstrakt
Liczba wyników

Znaleziono wyników: 12

Liczba wyników na stronie
Pierwsza strona wyników Pięć stron wyników wstecz Poprzednia strona wyników Strona / 1 Następna strona wyników Pięć stron wyników wprzód Ostatnia strona wyników

Wyniki wyszukiwania

Wyszukiwano:
w słowach kluczowych:  neurotransmitter system
help Sortuj według:

help Ogranicz wyniki do:
Pierwsza strona wyników Pięć stron wyników wstecz Poprzednia strona wyników Strona / 1 Następna strona wyników Pięć stron wyników wprzód Ostatnia strona wyników
1

Effects of xylazine on glutamate and GABA contents in the hippocampus and thalamencephal in the rat

100%
Yin B. S., Wang H. B., Gong D. Q., Li G. J., Gao L.
Bulletin of the Veterinary Institute in Puławy
|
2011
|
tom 55
|
nr 3
The purpose of the study was to define if anaesthetic action of xylazine could conceivably result from the potentiation of inhibitory neurotransmitters or the inhibition of excitatory neurotransmitter systems in the brain. Rats were injected with xylazine at a dose of 50 mg/kg b.w., and then the hippocampus and thalamencephal were removed at 0.1, 0.25, 0.5, 1, 1.5, 2, 4, and 6 h after the injection. Glutamate (Glu) and γ-aminobutyric-acid (GABA) were measured in the brain tissue by reversed-phase high-performance liquid chromatography. The results revealed that the hippocampus Glu level decreased significantly 0.1 h after the injection of xylazine, the thalamencephal GABA increased significantly 0.1 h after the injection, while the changes in hippocampus GABA and thalamencephal Glu were not significant. However, all of these changes returned to the normal level after 2 and 4 h, respectively. The results indicated the relative effects of xylazine on Glu and GABA levels in the hippocampus and thalamencephal.
2
Content available remote

Intermingled modulatory and neurotoxic effects of thimerosal and mercuric ions on electrophysiological responses to GABA and NMDA in hippocampal neurons

100%
Wyrembek P., Szczuraszek K., Majewska M. D., Mozrzymas J. W.
Journal of Physiology and Pharmacology
|
2010
|
tom 61
|
nr 6
3

Escape from shock versus escape from shock accompanied by a visual stimulus in rats

100%
Zielinski K., Savonenko A. V.
Acta Neurobiologiae Experimentalis
|
2000
|
tom 60
|
nr 4
Two groups of 15 rats each were trained in a shuttle box to escape foot-shock either unsignalled or presented in compound with a visual cue: darkness. The visual cue presented in shock compartment amplifies the behavioral tendency actually prevailing in the response repertory of the rat. During the 1st session the compound enhanced the species-specific flight resulting in shortening of the rat's escape latency. Thereafter, during subsequent sessions, darkness exaggerated resistance to enter the other compartment; thus escape latencies were longer under compounded than under unsignalled procedure. The darkness cue reduces the intertrial response rate relative to the unsignalled group. This latter finding supports the discrimination model of the effect, since the compound helps the animals to discriminate the illuminated "safe" period between trials from the aversive shock period. Our data seem to suggest that the darkness presented synchronously with escapable grid-shock acquires aversive properties.
4

Locomotor capacities after complete and partial lesions of the spinal cord

100%
Rossignol S., Chau C., Brustein E., Belanger M., Barbeau H., Drew T.
Acta Neurobiologiae Experimentalis
|
1996
|
tom 56
|
nr 1
5

Sensory conditioning and sensory stimulation do not affect GABA A receptor binding in the barrel field of mice

100%
Jablonska B., Skangiel-Kramska J.
Acta Neurobiologiae Experimentalis
|
1995
|
tom 55
|
nr 4
6

Spontaneous spike-wave discharges in rat neocortex and their relation to behaviour

100%
Gralewicz S., Wiaderna D., Stetkiewicz J., Tomas T.
Acta Neurobiologiae Experimentalis
|
2000
|
tom 60
|
nr 3
7

Effect of lateral hypothalamic lesion on sleep-waking pattern and EEG power spectra in the rat

100%
Jurkowlaniec E., Pracki T., Trojniar W., Tokarski J.
Acta Neurobiologiae Experimentalis
|
1996
|
tom 56
|
nr 1
8

The influence of repeated systemic penicillin injections at subconvulsive doses on spontaneous Spike-Wave Discharges in the rat

100%
Stankiewicz J., Gralewicz S.
Acta Neurobiologiae Experimentalis
|
1996
|
tom 56
|
nr 3
9

Social interactions in cats: regional brain monoamine distribution in dominant and submissive cats

80%
Krotewicz M., Romaniuk A.
Acta Neurobiologiae Experimentalis
|
1995
|
tom 55
|
nr 4
10

ITF mapping after drugs of abuse: pharmacological versus perceptional effects

80%
Ryabinin A. E.
Acta Neurobiologiae Experimentalis
|
2000
|
tom 60
|
nr 4
Analysis of inducible transcription factors (ITFs) expression is often applied to map drug-induced changes of neuronal activity in brain. Administration of cocaine and alcohol induces ITFs in a large number of brain structures. However, induction of ITFs in a brain region does not necessarily indicate a pharmacological effect of the drug in this brain region. Many of the brain regions could be activated by secondary effects. Perception of stimulus properties of the drug or locomotor effects of the drug are possible secondary effects. Anesthesia can block induction of ITFs by cocaine and alcohol suggesting that ITF expression in a majority of brain regions is more sensitive to secondary effects than to pharmacological effects of these drugs. In agreement with this hypothesis is our finding that the majority of brain regions responding with ITF expression to alcohol administration do not respond to voluntary alcohol self-administration in animals. Only a few brain regions show similar ITF induction after both administration and self-administration of this drug. Presumably these brain regions could be responding to pharmacological effects of alcohol. Given the low resolution of invasive techniques, ITF mapping experiments will continually contribute to our understanding of mechanisms of drug addiction and alcoholism.
11

Aging and beta-amyloid peptides decrease cholinergic receptor-mediated calcium increase in brain cortex synaptoneurosomes

80%
Samochocki M.
Acta Neurobiologiae Experimentalis
|
1998
|
tom 58
|
nr 1
12

The effect of glutamate uptake inhibitors on hippocampal evoked potentials in vitro

80%
El-Sherif Y., Singh N., Khan T., Wieraszko A.
Acta Neurobiologiae Experimentalis
|
1999
|
tom 59
|
nr 2
Pierwsza strona wyników Pięć stron wyników wstecz Poprzednia strona wyników Strona / 1 Następna strona wyników Pięć stron wyników wprzód Ostatnia strona wyników
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.