Wyniki wyszukiwania

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The role of tumor cells in the modification of T lymphocytes activity — the expression of the early CD69+, CD71+ and the late CD25+, CD26+, HLA/DR+ activation markers on T CD4+ and CD8+ cells in squamous cell laryngeal carcinoma. Part I

100%

Starska K., Glowacka E., Kulig A., Lewy-Trenda I., Brys M., Lewkowicz P.

Folia Histochemica et Cytobiologica

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2011

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tom 49

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nr 4

2

Prognostic value of the immunological phenomena and relationship with clinicopathological characteristics of the tumor — the expression of the early CD69plus, CD71plus and the late CD25plus, CD26plus, HLA/DRplus activation markers on T CD4plus and CD8plus lymphocytes in squamous cell laryngeal carcinoma. Part II

100%

Starska K., Glowacka E., Kulig A., Lewy-Trenda I., Brys M., Lewkowicz P.

Folia Histochemica et Cytobiologica

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2011

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tom 49

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nr 4

3

Changes of cough reflex sensitivity induced by cancer radiotherapy of chest and neck regions

100%

Javorkova N., Hajtmanova E., Kostkova L., Zamecnik L., Pecova R., Hanacek J., Tatar M.

Journal of Physiology and Pharmacology. Supplement

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2006

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tom 57

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nr 4

157-163

It is reasonable to suppose that airway mucosa can be damaged by irradiation applied to chest and neck regions. The inflammatory process is a consequence of an injury. Airway inflammation is one mechanism responsible for cough induction. So, one can suppose that radiotherapy (RT) focused on the patients' chest or neck may injure airway mucosa, which might change sensitivity of the nerve-endings mediating the cough reflex. The purpose of this study was to examine cough reflex sensitivity (CRS) in patients who underwent RT in the chest and neck regions. CRS test using capsaicin was performed in patients with breast cancer (Group A, n=19), and with lung or neck cancer in (Group B, n=14) who underwent RT. Capsaicin aerosol in doubled concentrations (0.49-1000 µM) was inhaled by a single breath. CRS was defined as the lowest capsaicin concentration that evoked 2 or more coughs (C2). Radiation doses ranged from 40 to 70 Gy. Capsaicin cough challenge was performed before and then in the 2nd and 5th week of RT. We observed a significantly reduced value of C2, i.e., increased cough reflex sensitivity, in Group B in the 2nd week of RT (P= 0.04). We conclude that CRS in the lung or neck cancer patients undergoing RT is significantly enhanced, which could result from injury to the nerve endings in airway mucosa.

4

Influence of chest gamma-irradiation on cough response in awake guinea pigs

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Brozmanova M., Javorkova N., Hajtmanova E., Zamecnik L., Javorka M., Hanacek J., Tatar M.

Journal of Physiology and Pharmacology. Supplement

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2007

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tom 58

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nr 5

Ograniczanie wyników

2 Folia Histochemica et Cytobiologica

2 Journal of Physiology and Pharmacology. Supplement

2 Brys M.

2 Glowacka E.

2 Hajtmanova E.

2 Hanacek J.

2 Javorkova N.

2 Kulig A.

2 Lewkowicz P.

2 Lewy-Trenda I.

2 Starska K.

2 Tatar M.

2 Zamecnik L.

1 Brozmanova M.

1 Javorka M.

1 Kostkova L.

1 Pecova R.

2 2011

1 2007

1 2006

The role of tumor cells in the modification of T lymphocytes activity — the expression of the early CD69+, CD71+ and the late CD25+, CD26+, HLA/DR+ activation markers on T CD4+ and CD8+ cells in squamous cell laryngeal carcinoma. Part I

Changes of cough reflex sensitivity induced by cancer radiotherapy of chest and neck regions

Influence of chest gamma-irradiation on cough response in awake guinea pigs