Wyniki wyszukiwania

1

Bioimpedance vector pattern in head and neck squamous cell carcinoma

100%

Malecka-Massalska T., Smolen A., Zubrzycki J., Lupa-Zatwarnicka K., Morshed K.

Journal of Physiology and Pharmacology

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2012

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tom 63

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nr 1

2

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Secretion of hydrolytic enzymes by fungal strains, isolated from patients with malignant tumors of head and neck, before, during and after radiotherapy

100%

Moqbil S., Kurnatowski P.

Annals of Parasitology

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2012

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tom 58

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nr 1

One method of treatment used in cancer therapy is radiotherapy which can injure the oral, pharynx or larynx mucosa and predisposes tissue to the development of fungal infections. The aim of the study paper was the mycological examinations of swabs from the oral cavity and pharynx of patients obtained prior to, in week 3, on the last day of and 3 weeks after radiotherapy, as well as isolation of fungi and identification of the selected parameter of strains pathogenecity, i.e. hydrolytic enzyme release. Forty-three patients with oral cavity, pharynx or larynx carcinoma were examined at four points during a course of radiotherapy: before treatment, in week 3 of treatment, on the last day of treatment and 3 weeks afterwards. The mycological examination was conducted based on a procedure introduced in the Department of Biology and Medical Parasitology, Medical University of Lodz. The activity of the hydrolytic enzymes was evaluated with a bioMerieux API ZYM test kit. More than 2/3 of the patients (68.2%) were found to have a fungal infection in the first examination, 4/5 (80%) in the second, about 3/5 (57.1%) in the third and all (100%) in the last examination. The release of enzymes varied, and on different stages show different inactive enzymes: at the start, α-chymotrypsin and α-mannosidase; at 3 weeks, β-glucuronidase and α-mannosidase; at the end, α-chymotrypsin; at 3 weeks after the end, trypsin, α-chymotrypsin, α-galaktosidase and α-fucosidase. The most frequent species isolated from the patients treated by radiotherapy is Candida albicans and C. glabrata. The latter is characterized by resistance to the majority of antimycotic medications. The isolated strains are characterized by the highest activity of leucine arylamidase, acid phosphatase and naphthol – AS-BI-phosphohydrolase. Considering the enzymes produced, most of the strains can be included to biotypes D₃, C₆ and A.

3

Dendritic cells based immunotherapy of patient with chondrosarcoma - case report

100%

Tabarkiewicz J., Radej S., Hus I., Wasiak M., Wdowiak P., Giannopoulos K., Piechnik B., Klos A., Dmoszynska A., Rolinski J.

Folia Histochemica et Cytobiologica

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2008

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tom 46

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nr 2

165-170

4

Histopathological case report of high grade salivary duct carcinoma

100%

Borevec J., Cegan M., Mala K., Harmash N., Chramosta P., Kobierzycki C., Bobek V.

Folia Histochemica et Cytobiologica

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2015

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tom 53

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nr 4

5

A monument of inefficiency: The presumed course of the recurrent laryngeal nerve in sauropod dinosaurs

100%

Wedel M. J.

Acta Palaeontologica Polonica

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2012

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tom 57

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nr 2

The recurrent laryngeal nerve is an often cited example of “unintelligent design” in biology, especially in the giraffe. The nerve appears early in embryonic development, before the pharyngeal and aortic arches are separated by the development of the neck. The recurrent course of the nerve from the brain, around the great vessels, to the larynx, is shared by all extant tetrapods. Therefore we may infer that the recurrent laryngeal nerve was present in extinct tetrapods, had the same developmental origin, and followed the same course. The longest−necked animals of all time were the extinct sauropod dinosaurs, some of which had necks 14 meters long. In these animals, the neurons that comprised the recurrent laryngeal nerve were at least 28 meters long. Still longer neurons may have spanned the distance from the end of the tail to the brainstem, as in all extant vertebrates. In the longest sauropods these neurons may have been 40–50 meters long, probably the longest cells in the history of life.

6

Free DIEP-flap reconstruction of tumour related defects in head and neck

100%

Leonhardt H., Mai R., Pradel W., Markwardt J., Pinzer T., Spassov A., Lauer G.

Journal of Physiology and Pharmacology. Supplement

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2008

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tom 59

|

nr 5

59-67

7

Retroscalenic course of the transverse cervical artery with the suprascapular artery travelling through the suprascapular notch

100%

Tubbs R. S., Shoja M. M., Shokouhi G., Loukas M., Oakes W. J.

Folia Morphologica

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2007

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tom 66

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nr 1

Variations involving the cervical portion of the vagus nerve are seemingly very rare. We report an adult male found to harbour a right cervical vagus nerve that crossed anterior to the right common carotid artery to terminate in the lateral aspect of the thyroid gland. A very small continuation of this nerve was found to continue distally into the thorax. Histologically, this part of the vagus nerve did not contain ganglion or other cell bodies. There were no heterologous inclusions (thyroid, parathyroid, thymus, salivary gland or branchial cleft remnants) present. Although grossly there was a connection into the thyroid gland, this was not observed histologically. No signs of trauma were found to the ipsilateral neck region. We hypothesise that this variation is due to entanglement between the thyroid gland and cervical vagus nerve during development. This rare variation might be considered by the clinician who operates in the cervical region or interprets imaging of the neck. To our knowledge, a vagus nerve with the above described morphology has not been described.

8

Microscopic study of muscle spindles in recti muscles of human fetal eye

100%

Wojtowicz-Kaczmarek K.

Folia Morphologica

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1997

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tom 56

|

nr 2

9

An unreported variation of the cervical vagus nerve: anatomical and histological observations

100%

Tubbs R. S., Loukas M., Shoja M. M., Blevins D., Humphrey R., Chua G. D., Kelly D. R., Oakes W. J.

Folia Morphologica

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2007

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tom 66

|

nr 2

Variations involving the cervical portion of the vagus nerve are seemingly very rare. We report an adult male found to harbour a right cervical vagus nerve that crossed anterior to the right common carotid artery to terminate in the lateral aspect of the thyroid gland. A very small continuation of this nerve was found to continue distally into the thorax. Histologically, this part of the vagus nerve did not contain ganglion or other cell bodies. There were no heterologous inclusions (thyroid, parathyroid, thymus, salivary gland or branchial cleft remnants) present. Although grossly there was a connection into the thyroid gland, this was not observed histologically. No signs of trauma were found to the ipsilateral neck region. We hypothesise that this variation is due to entanglement between the thyroid gland and cervical vagus nerve during development. This rare variation might be considered by the clinician who operates in the cervical region or interprets imaging of the neck. To our knowledge, a vagus nerve with the above described morphology has not been described.

10

Effects of cigarette smoke borne reactive nitrogen species on salivary alpha-amylase activity and protein modifications

80%

Weiner D., Khankin E. V., Levy Y., Reznick A. Z.

Journal of Physiology and Pharmacology. Supplement

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2009

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tom 60

|

nr 5

11

Morphometric characteristics of the alimentary canal in American mink (Mustela vison Schreber, 1777)

80%

Wach J., Nowicki W., Brudnicki W., Skoczylas B., Grzywacz K., Kirkillo-Stacewicz K., Brudnicki A.

Electronic Journal of Polish Agricultural Universities. Series Animal Husbandry

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2011

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tom 14

|

nr 1

12

The cervical vertebrae of the Late Cretaceous abelisaurid dinosaur Carnotaurus sastrei

80%

Mendez A. H.

Acta Palaeontologica Polonica

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2014

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tom 59

|

nr 3

The cervical vertebral series of Carnotaurus sastrei from Argentina is described in detail, and compared with Majungasaurus crenatissimus from Madagascar, both Late Cretaceous (Maastrichtian) in age. Notable differences in the morphology of the cervical vertebrae, especially in the shape and development of the epipophysis and the neural spines, are observed between these two genera. These differences show a neck much more robust in Carnotaurus than in Majungasaurus, may be linked to the evolution of the clade in relation to the divergence time since the two genera shared a common ancestor, and functionally may relate to the feeding function associated to the extreme reduction of the forelimbs.

13

Kinase expression and chromosomal rearrangements in papillary thyroid cancer tissues: investigations at the molecular and microscopic levels

80%

Weier H.-U. G., Kwan J., Lu C.-M., Ito Y., Wang M., Baumgartner A., Hayward S. W., Weier J. F., Zitzelsberger H. F.

Journal of Physiology and Pharmacology. Supplement

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2009

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tom 60

|

nr 4

14

Signs, symptoms and the prevalence of fungi detected from the oral cavity and pharynx of radiotherapy subjects with head and neck tumors, and their susceptibility to chemotherapeutics

80%

Kurnatowski P., Moqbil S., Kaczmarczyk D.

Annals of Parasitology

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2014

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tom 60

|

nr 3

Radio- and chemotherapy for malignant neoplasms, especially in head and neck region, is associated with a greater risk of fungal infections due to secondary alterations in the mucous membranes. The study had three aims: 1. to determine the signs and symptoms which occur among patients undergoing radiotherapy; 2. to determine the fungi prevalence in the mouth and throat of patients before, during and after radiotherapy; 3. to examine the sensitivity of strains to antimycotic drugs. The study comprised 44 patients (11 female, 33 male) with head and neck cancers, examined at the following stages: before radiotherapy (44 patients – batch 1), 3rd week of therapy (30 of the 44 patients – batch 2), last day of therapy (28 of batch 2 – batch 3) and the 6th week after completion of radiotherapy (10 of batch 3 – batch 4). Clinical examination was performed and mycological status was estimated from an oral rinse on a selected medium. The fungal strains were isolated and sensitivity to antifungal drugs was determined. The most common symptoms were pain, dysphagia, and dysgeusia. Physical examination revealed signs of mucositis mainly among patients from batches 2 and 3. The presence of fungi in the mouth and throat was noted in over 2/3 (66.2%) of the patients from batch 1, and in 4/5 (80%) of batch 2. The fungi were detected in over half (57.1%) of patients from batch 3 and also in patients from batch 4. In all cases, fungi of various Candida species were identified: 6 species in batch 1, 8 in batch 2, 6 in batch 3 and 5 in batch 4. The most frequently detected species was C. albicans, constituting 40–60%; the other species detected are known to be resistant to antimycotic drugs. The isolated strains were the most sensitive to nystatin and miconazole, and the least to ketoconazole and fluconazole. Conclusions: 1. Patients undergoing radiotherapy complain of pain, dysphagia, and dysgeusia; in most cases mucositis is diagnosed. 2. The high prevalence of fungi in the mouth and throat of patients treated by radiotherapy reinforces the need to perform mycological examinations in this group of patients to detect fungi, identify their species and determine of their sensitivity to drugs in order to prevent complications. 3. The species most frequently isolated from the patients are C. albicans and C. glabrata. The latter is characterized by resistance to the majority of antimycotic medications. 4. Most of the isolated strains are sensitive to nystatin and miconazole (applied locally) and to itraconazole (absorbed from the gastrointestinal tract).

15

DNA damage and repair in lymphocytes of normal individuals and cancer patients: studies by the comet assay and micronucleus tests

80%

Palyvoda O., Polanska J., Wygoda A., Rzeszowska-Wolny J.

Acta Biochimica Polonica

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2003

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tom 50

|

nr 1

A population study is reported in which the DNA damage induced by y-radiation (2 Gy) and the kinetics of the subsequent repair were estimated by the comet and micronucleus assays in isolated lymphocytes of 82 healthy donors and patients with head and neck cancer before radiotherapy. The parameters of background and radiation-induced DNA damage, rate of repair, and residual non-repaired damage were measured by comet assay, and the repair kinetics for every donor were computer-fitted to an exponential curve. The level of background DNA damage before irradiation measured by comet assay as well as the level of micronuclei were significantly higher in the head and neck cancer patient group than in the healthy donors, while the parameters of repair were widely scattered in both groups. Cancer patient group contained significantly more individuals, whose irradiated lymphocytes showed high DNA damage, low repair rate and high non-repaired DNA damage level. Lymphocytes of donors belonging to this subgroup showed significantly lower inhibition of cell cycle after irradiation.

16

Scanning electron microscopy of the scolex and neck of the tapeworm Cathetocephalus thatcheri [Cestoda, Tetraphyllidea] from the sandbar shark Carcharhinus plumbeus [Chondrichthyes, Elasmobranchii]

80%

Conn D. B., Whittaker F. H., Curless W. W.

Acta Parasitologica

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2004

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tom 49

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nr 1

Scanning electron microscopy of the scolex and neck of the cestode Cathetocephalus thatcheri confirmed earlier light-microscope descriptions showing that the scolex consists of a single apical lenticular adhesive complex, oriented transverse to the long axis of the strobila. The apical region of the scolex consists of a medial ridge from which extend numerous pairs of short bilamellate septa. On each side of the medial ridge, along its entire length, is a ridge in the form of sinusoidal wave that forms a loop around each of the septa. The tegument of the anterior surface of the medial ridge is formed into numerous tegumental folds that are aligned perpendicular to the long axis of the ridge. Posteriorly, the scolex has a rugose surface and forms a collar or lip around the upper part of the adherent surface. The sinusoidal ridges are continuous around the ends of the scolex. At the ends, the medial ridge tapers considerably. The tegument of the neck bears numerous papillae. No microtriches were observed on any part of the scolex or neck.

17

Detection of the status of tumour-infiltrating CD4plus T-cell subpopulations in squamous cell carcinoma of the head and neck [HNSCC] using real-time RT-PCR detection of CD4 mRNA

80%

Smerkolj S., Volavsek M., Glavac D.

Cellular and Molecular Biology Letters

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2007

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tom 12

|

nr 2

Several studies have reported tumour infiltrating CD4+ T cells as a favourable prognostic factor in some types of cancer. We investigated 37 head and neck squamous cell carcinomas (HNSCC) at different stages, using immunohistochemical staining for CD4+ infiltrates and real-time reverse transcription polymerase chain reaction (RT-PCR) detection of CD4 mRNA. The CD4+ infiltrates were evaluated and expressed as a percentage according to the ratio of CD4+ T cells to epithelial cells in the cancer cell nests and to the overall inflammatory cell infiltrate in the tumor stroma. The CD4 mRNA expression level strongly correlated with the CD4+ infiltration score in the cancer epithelium (rs = 0.858, P < 0.001) and in the cancer stroma (rs = 0.797, P < 0.001). These results indicate that the real-time RT-PCR assay is a sensitive and reliable method for the detection of CD4 mRNA, and that it could be used to reassess CD4+ infiltration status in resected specimens from patients with HNSCC.

18

Ocena wpływu mikrokapsułkowanego chlorku sodu na stan mikrobiologiczny mięsa ze schabu i z karkówki przechowywanego w warunkach chłodniczych i zamrażalniczych

71%

Danyluk B., Medynski A., Pospiech E., Lyczynski A., Grzes B.

Żywność Nauka Technologia Jakość

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2004

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tom 11

|

nr 2

32-45

Celem pracy było określenie wpływu dodatku mikrokapsułkowanego chlorku sodu, azotanu(III) sodu i kwasu mlekowego na stan mikrobiologiczny mięsa schabu i karkówki. Mięso przechowywano w warunkach chłodniczych (2 i 14 dób) i zamrażalniczych (3 i 9 miesięcy), po uprzednim umieszczeniu go w woreczkach z folii laminowanej PAPE, zamkniętych próżniowo. Z reguły stwierdzano istotnie wyższe zanieczyszczenie bakteriami tlenowymi mięsa karkówki w porównaniu ze schabem zarówno po 2, jak i po 14 dobach przechowywania w chłodni. Dodanie, oprócz soli, azotanu(III) sodu i kwasu mlekowego miało korzystny wpływ na trwałość mikrobiologiczną mięsa przechowywanego w chłodni przez okres 2 tygodni. Wydłużenie czasu zamrażalniczego przechowywania mięsa z 3 do 9 miesięcy powodowało redukcję liczby bakterii tlenowych w materiale zawierającym tylko sól, a wzrost bakterii zakwaszających, niezależnie od rodzaju stosowanej substancji dodatkowej. Przyczyniło się także do znacznej redukcji bakterii z grupy coli w mięsie schabu, czego nie zaobserwowano w przypadku karkówki. Użycie mikrokapsułkowanej soli nie stanowiło zagrożenia mikrobiologicznego mięsa nawet po 14 dniowym przechowywaniu.

19

Przydatność ubocznych artykułów z uboju kaczek do oceny składu tkankowego ich tuszek

61%

Michalik D., Bochno R.

Acta Academiae Agriculturae ac Technicae Olstenensis. Zootechnica

|

1988

|

tom 31

Ograniczanie wyników

Bioimpedance vector pattern in head and neck squamous cell carcinoma

Secretion of hydrolytic enzymes by fungal strains, isolated from patients with malignant tumors of head and neck, before, during and after radiotherapy

Dendritic cells based immunotherapy of patient with chondrosarcoma - case report

Histopathological case report of high grade salivary duct carcinoma

A monument of inefficiency: The presumed course of the recurrent laryngeal nerve in sauropod dinosaurs

Free DIEP-flap reconstruction of tumour related defects in head and neck

Retroscalenic course of the transverse cervical artery with the suprascapular artery travelling through the suprascapular notch

Microscopic study of muscle spindles in recti muscles of human fetal eye

An unreported variation of the cervical vagus nerve: anatomical and histological observations

Effects of cigarette smoke borne reactive nitrogen species on salivary alpha-amylase activity and protein modifications

Morphometric characteristics of the alimentary canal in American mink (Mustela vison Schreber, 1777)

The cervical vertebrae of the Late Cretaceous abelisaurid dinosaur Carnotaurus sastrei

Kinase expression and chromosomal rearrangements in papillary thyroid cancer tissues: investigations at the molecular and microscopic levels

Signs, symptoms and the prevalence of fungi detected from the oral cavity and pharynx of radiotherapy subjects with head and neck tumors, and their susceptibility to chemotherapeutics

DNA damage and repair in lymphocytes of normal individuals and cancer patients: studies by the comet assay and micronucleus tests

Scanning electron microscopy of the scolex and neck of the tapeworm Cathetocephalus thatcheri [Cestoda, Tetraphyllidea] from the sandbar shark Carcharhinus plumbeus [Chondrichthyes, Elasmobranchii]

Detection of the status of tumour-infiltrating CD4plus T-cell subpopulations in squamous cell carcinoma of the head and neck [HNSCC] using real-time RT-PCR detection of CD4 mRNA

Ocena wpływu mikrokapsułkowanego chlorku sodu na stan mikrobiologiczny mięsa ze schabu i z karkówki przechowywanego w warunkach chłodniczych i zamrażalniczych

Przydatność ubocznych artykułów z uboju kaczek do oceny składu tkankowego ich tuszek