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Fluorescence decay time distribution analysis of cyclic enkephalin analogues; Influence of solvent and Leu configuration in position 5 on conformation

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Malicka J., Ganzynkowicz R., Groth M., Czaplewski C., Karolczak J., Liwo A., Wiczk W.

Acta Biochimica Polonica

2001

tom 48

nr 1

Lifetime distribution analysis were performed to study the influence of Leu configuration in position 5 on changes of the peptide chain of cyclic analogues of enkephalins containing a fluorescence donor and acceptor in different solvents. The configuration change of Leu5 in all the analogues of enkephalins studied which contain donor-acceptor pairs has no apparent influence on Trp lifetime distributions. In contrast, there is a significant solvent effect on the shape of lifetime distribution.

Ograniczanie wyników

1 Acta Biochimica Polonica

1 Czaplewski C.

1 Ganzynkowicz R.

1 Groth M.

1 Karolczak J.

1 Liwo A.

1 Malicka J.

1 Wiczk W.

1 2001

Wyniki wyszukiwania

Fluorescence decay time distribution analysis of cyclic enkephalin analogues; Influence of solvent and Leu configuration in position 5 on conformation