Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników

Znaleziono wyników: 12

Liczba wyników na stronie
Pierwsza strona wyników Pięć stron wyników wstecz Poprzednia strona wyników Strona / 1 Następna strona wyników Pięć stron wyników wprzód Ostatnia strona wyników

Wyniki wyszukiwania

Wyszukiwano:
w słowach kluczowych:  nadtlenki lipidowe
help Sortuj według:

help Ogranicz wyniki do:
Pierwsza strona wyników Pięć stron wyników wstecz Poprzednia strona wyników Strona / 1 Następna strona wyników Pięć stron wyników wprzód Ostatnia strona wyników
The aim of this study was the assessment the effects of vegetarian nutrition mode (lactoovovegetarian, lactovegetarian, vegan, semivegetarian) on the blood levels of lipid peroxides determined indirectly as thiobarbituric acid-reacting substance (TBARS) and superoxide dismutase activity (SOD) as well as catalase activity (CAT). The studied group of vegetarians comprised 170 subjects who were compared with 80 controls living on traditional diet. A statistically significantly higher of TBARS (3.61 ± 0.47 nmol/ml) and lower SOD activity (1631 ± 200 U/gHb) and CAT activity (48.2 ± 11.6 U/gHb) were found in vegetarians as compared to nonvegetarians (3.21 ± 0.43 TBARS, 1719 ± 172 SOD and 62.2 ± 15.6 CAT). Higher TBARS level in vegetarians depended, in some degree, on the type of vegetarian diet. The highest TBARS level was found in the vegan group (3.87 ± 0.53 nmol/ml). The obtained results show that vegetarian diets may contain factors inhibiting the antioxidant enzymes and diets rich in polyunsaturated fatty acids can be the source of lipid peroxides.
The purpose of the study was the measurement of superoxide dismutase (SOD) activity in erythrocytes in 43 patients with acute myocardial infarction on the lst-2nd day after the onset of clinical symptoms, and elucidation of the relationship between this enzyme activity and the blood levels of antioxidant vitamins and lipid peroxides determined as the amount of substances reacting with thiobarbituric acid (TBARS). The effect of vitamin C and E supplementation for period of 14 days on SOD activity in these patients was also studied. A statistically significantly lower TBARS level was found in patients with SOD activity over 1700 u/gHb, and higher TBARS level in patients with low SOD activity at the time of infraction onset. In the patients with erythrocyte SOD activity over 1700 u/gHb higher serum levels of ascorbic acid and carotenes were found. Administration of antioxidant vitamins during 14 days to patients with clinical symptoms of myocardial infraction raised SOD activity in patients with initially low activity.
The aim of the retrospective study conducted over a period of five years was to assess the changes occurring in peroxidation processes in the blood of elderly people, and to find out possible correlations between the products of lipid peroxidation and the antioxidants, that is vitamins and enzymes with antioxidant activity. The study was carried out in a group of men and women born between 1921 and 1923. In 1992, 157 people (73 men and 84 women) participated in the study. In 1997 the second study was done on 103 people from the initial groups (43 men and 60 women). The concentration of lipid peroxides (TBARS), the activity of superoxide dismutase (SOD) and catalase (KAT) was measured in blood samples taken from an antecubital vein, from fasting subjects. Correlation coefficients were determined between TBARS, SOD, KAT and antioxidant vitamins and plasma lipids. It was found that over that period of five years the TBARS level decreased statistically significantly, on the average by 25%, in the plasma of men, and by 16% in that of women, as compared to the year 1992. SOD activity increased in blood haemolysates statistically significantly by 9% in men and by 22% in women. Over the same time period KAT activity decreased by 18% in men and by 11% women. A positive correlation was noted between TBARS and SOD activity both in 1992 and in 1997. TBARS level was negatively correlated with tocopherol level and cumulative antioxidant index in the blood of these subjects. In 1992 a positive correlation was demonstrated between TBARS and total cholesterol concentration. A positive correlation between TBARS and LDL-cholesterol was noted both in 1992 and 1997. During the five-year period of the study LDL-cholesterol level was positively correlated with SOD activity.
Celem pracy było zbadanie czy palmitynian retinylu redukuje stres oksydacyjny wywołany wysiłkiem fizycznym. Badania przeprowadzono na rosnących szczurach samcach rasy Wistar, które przez 10 dni biegały na bieżni z prędkością przesuwu 20 m/min. Szczurom podawano palmitynian retinylu w ilości 7,5, 15 lub 60 µg dziennie na zwierzą. Po tym okresie w osoczu oznaczano poziom retinolu, nadtlenki lipidowe i potencjał anty oksydacyjny oraz estry retinyłu w wątrobie. Stwierdzono, że palmitynian retinylu redukował stres oksydacyjny wywołany wysiłkiem fizycznym, a efektywność tego procesu nie zależała od dawki podanego palmitynianu.
In patients with myocardial infarction and in control healthy subjects the serum conmiration of cuitioxidalive vitamins (tocopherol, ascorbic acid, retinol, carotenes) and of pid peroxides (TBA-RS) were determined. One group of the studied, patients besides roune treatment received orally ascorbic acid and d,l,α -tocopherol acetale αα 600 mg/day for 14 days, while the other placebo. An increased intensity of peroxidatire processes in the course of acute myocardial infarction and unsatisfactory serum antioxidative vitamin levels were found. Mean serum lipid peroxide level in non-supplemented group increased, in vitamin-supplemented group was supressed.
Badano wpływ soli kadmu na zawartość nadtlenków lipidowych i aktywność enzymów przeciwutleniających w wątrobie ciężarnej samicy oraz wątrobie płodowej i siedmiodniowego szczura. Zatruwanie solami kadmu przez 20 dni powodowało wzrost poziomu peroksydacji lipidów i obniżenie aktywności enzymatycznej obrony przeciwutleniającej w wątrobie matczynej i płodowej. Zmiany te ( za wyjątkiem spadku aktywności reduktazy glutationowej) nie utrzymywały się w wątrobie siedmiodniowego szczura. Podawanie witaminy E obniżało poziom nadtlenków lipidowych w badanych narządach.
Pierwsza strona wyników Pięć stron wyników wstecz Poprzednia strona wyników Strona / 1 Następna strona wyników Pięć stron wyników wprzód Ostatnia strona wyników
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.