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The Kedem-Katchalsky equations as applied for describing substance transport across biological membranes

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Kargol A., Kargol M., Przestalski S.

Cellular and Molecular Biology Letters

1997

tom 02

nr 2

The classical version of the Kedem-Katchalsky equations is suitable for describing substance transport in membrane systems with well-stirred bathing solutions. However, when dealing with biological reality we are faced with a more complicated situation. For instance, in the living cell one can distinguish the central bulk area where the cytoplasm is well stirred due to its natural streaming and a certain relatively thin layer adjacent to the plasma membrane where there is no stirring. In such a situation, the passive transport of substance can be well described using the Kedem-Katchalsky equations in their more general form [1], The equations can, however, be applied provided the membrane boundary unstirred layers of cytoplasm are treated as diffusion layers. This has been shown in detail in the present work.

Ograniczanie wyników

1 Cellular and Molecular Biology Letters

1 Kargol A.

1 Kargol M.

1 Przestalski S.

1 1997

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The Kedem-Katchalsky equations as applied for describing substance transport across biological membranes