Preferencje help
Polish version English version Język
Widoczny [Schowaj] Abstrakt
Liczba wyników

Znaleziono wyników: 9

Liczba wyników na stronie
Pierwsza strona wyników Pięć stron wyników wstecz Poprzednia strona wyników Strona / 1 Następna strona wyników Pięć stron wyników wprzód Ostatnia strona wyników

Wyniki wyszukiwania

Wyszukiwano:
w słowach kluczowych:  mammary adenocarcinoma
help Sortuj według:

help Ogranicz wyniki do:
Pierwsza strona wyników Pięć stron wyników wstecz Poprzednia strona wyników Strona / 1 Następna strona wyników Pięć stron wyników wprzód Ostatnia strona wyników
1

Transplantable mouse 16/C mammary adenocarcinoma as a model in experimental cancer therapy. II. Modification of tumor-host interactions by therapeutic procedures

100%
Rak J., Strzadala L., Kusnierczyk H., Radzikowski C.
Archivum Immunologiae et Therapiae Experimentalis
|
1989
|
tom 37
|
nr 3-4
2

Transplantable mouse mammary adenocarcinoma 16/C as a model in experimental cancer therapy. III. Sensitivity to antitumor drugs

100%
Rak J., Kusnierczyk H., Strzadala L., Klosiewicz S., Radzikowski C.
Archivum Immunologiae et Therapiae Experimentalis
|
1989
|
tom 37
|
nr 3-4
3

Expression of E-cadherin, beta-catenin and Ki-67 antigen and their reciprocal relationships in mammary adenocarcinomas in bitches

100%
Nowak M., Madej J. A., Dziegiel P.
Folia Histochemica et Cytobiologica
|
2007
|
tom 45
|
nr 3
4

Correlation in the expression of HER2 receptor and Ki-67 antigen in mammary adenocarcinomas in bitches

100%
Nowak M., Madej J. A., Dziegiel P.
Bulletin of the Veterinary Institute in Puławy
|
2005
|
tom 49
|
nr 3
5

Immunohistochemical localization of COX2 in cells of mammary edenocarcinomas in bitches as related to tumour malignancy grade

100%
Nowak M., Madej J. A., Dziegiel P.
Bulletin of the Veterinary Institute in Puławy
|
2005
|
tom 49
|
nr 4
6
Content available remote

Cell-specific cytotoxic effect of pyrazole derivatives on breast cancer cell lines MCF7 and MDA-MB-231

80%
Lehmann T. P., Kujawski J., Kruk J., Czaja K., Bernard M. K., Jagodzinski P. P.
Journal of Physiology and Pharmacology
|
2017
|
tom 68
|
nr 2
7
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

Density of tumor-associated macrophages (TAMs) and expression of their growth factor receptor MCSF-R and CD14 in canine mammary adenocarcinomas of various grade of malignancy and metastasis

80%
Krol M., Pawlowski K., Majchrzak K., Dolka I., Abramowicz A., Szyszko K., Motyl T.
Polish Journal of Veterinary Sciences
|
2011
|
tom 14
|
nr 1
Several years ago, the presence of macrophages in the tumor microenvironment was thought to be an inflammatory response to kill the cancer cells. Now, this is clear that the inflammatory cells that exit blood vessels and migrate to the tumor tissue play an important role in cancer progression. Various cells present in the tumor microenvironment enhance cancer growth and invasiveness by secretion of tumor-enhancing products. That is why tumors should not be treated as only aggregates of cancer cells but as separate structures. Macrophages form a major component of the inflammatory infiltration in tumors, where they are termed tumor-associated macrophages (TAMs). To the best of our knowledge, up-to-date there were no studies on tumor associated macrophages and the role of the tumor microenvironment in tumor invasion/metastasis in dogs. This is the first study performed to asses if the number of TAMs and expression of MCSF-R (macrophages colony stimulating factor receptor) and CD14 (LPS co-receptor) are associated with the grade of tumor malignancy and its ability to metastasize. We have performed immunohistochemical analysis of 50 canine mammary adenocarcinomas of various grade of malignancy (1st, 2nd, 3rd) and tumors that gave local or distant metastases. The results indicate that in dogs, similarly to humans and mice, the number of tumor associated macrophages is related to the cancer ability to metastasize. Our results also indicate that the expression of MCSF-R and, what is particularly new finding, CD14 is associated with tumor malignancy and its ability to metastasize. Hence, these molecules play a role in tumor progression, metastasis and microenvironment interactions. These results show that in dogs we should treat the tumor as a whole organ rather than just try to eliminate the cancer cells.
8

Immunohistochemical localisation of telomerase in mammary adenocarcinoma in bitches

80%
Nowak M., Madej J. A., Dziegiel P., Dzimira S.
Bulletin of the Veterinary Institute in Puławy
|
2008
|
tom 52
|
nr 1
The studies were aimed at immunohistochemical determination of telomerase expression in cells of primary adenocarcinomas in mammary glands of bitches. Moreover, it was aimed at comparing the obtained results with an extent of Ki-67 antigen expression, which reflects the proliferation rate of tumour cells. Material for the studies was sampled during surgery in 35 bitches of various breed, ranging in age from 5 to 14 years, which developed mammary tumour. Using histopathology, the tumours were verified as representing adenocarcinomas. This was followed by immunohistochemical reactions for the detection of telomerase and Ki-67 expression. The obtained preparations were photographed and the images were subjected to computer-assisted analysis using the MultiScaneBase V 14.02 software. The obtained mean positive correlation (r = 0.26) between the expression of Ki-67 proliferative antigen and that of telomerase in mammary adenocarcinoma of bitches points at the involvement of the enzyme in neoplastic processes in animals, in an analogy to breast cancers in women.
9

Metastasis of mammary carcinoma to myocardium in a dog: clinical and morphological correlation

80%
Nowak M., Noszczyk-Nowak A., Slawuta P., Nowaczyk R., Polanska J.
Bulletin of the Veterinary Institute in Puławy
|
2007
|
tom 51
|
nr 2
A case of a widespread neoplastic process, originating from the mammary gland in mongrel bitch, weighing 27 kg and aging 7 years, was described. In the patient, blood morphology, blood biochemical parameters, gasometry of arterial blood, chest X-ray, and heart ECG and USG were determined. ECG record demonstrated elevation of ST-T segment by 0.2-0.3 mV in I, aVL leads and a downward- sloping depression in III and aVR leads. The alterations pointed with high probability to infarction in the lateral wall of the left ventricle. Following demonstration by imaging tests of numerous tumours in the chest, the dog was subjected to euthanasia. Upon autopsy, apart from the primary tumour in the mammary gland, numerous tumours were demonstrated in inner organs, including myocardium. Histopathology confirmed neoplastic growth of adenocarcinoma type. In the vicinity of the tumour localised in the left cardiac ventricle, microscopic examination disclosed regions of cardiomyocyte necrosis, which corroborated the preliminary diagnosis of infarction.
Pierwsza strona wyników Pięć stron wyników wstecz Poprzednia strona wyników Strona / 1 Następna strona wyników Pięć stron wyników wprzód Ostatnia strona wyników
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.