Wyniki wyszukiwania

1

The expression of GST isoenzymes and p53 in non-small cell lung cancer

100%

Oguztuzun S., Aydin M., Demirag F., Yazici U., Ozhavzali M., Kilic M., Iscan M.

Folia Histochemica et Cytobiologica

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2010

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tom 48

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nr 1

122-127

2

Primary pulmonary adenocarcinoma in roe deer - a case report

100%

Bednarski M., Wimonc M., Kolenda R., Wleklinski E., Krol D., Houszka M.

Medycyna Weterynaryjna

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2019

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tom 75

|

nr 06

Lung adenocarcinoma develops after the neoplastic transformation of pneumocytes or bronchial epithelium. It is chronic and slowly progressive in nature and the clinical signs are only seen in cases that have developed tumours of considerable size. There has been no report of lung adenocarcinoma in game animals. This case study reports a lung adenocarcinoma in a 4-year-old dead roe deer (Capreolus capreolus) from the Forest District Piaski, Greater Poland Province of Poland. During necropsy, a large mass measuring 15 × 20 cm was found in the caudal lobe of the right lung. The tumour was of grey or pinkish-grey colour, solid texture and had a clear delineation between the affected and non-affected areas. In the remaining lobes, numerous small nodules of 2-20 mm in diameter with a similar structure were found. A great deal of mucoid and mucopurulent fluid throughout the bronchial tree was observed. The thoracic lymph nodes were found enlarged. The histological analysis identified the large mass found as bronchoalveolar papillary lung adenocarcinoma. The PCR for JSRV was performed and the result was negative. To the best of our knowledge, this is the first report of the lung adenocarcinoma in a roe deer.

3

The influence of selected environmental factors on lung cancer incidence in immigrant population of industrial areas

100%

Juszko-Piekut M., Kolosza Z., Mozdzierz A.

Polish Journal of Environmental Studies

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2004

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tom 13

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nr Suppl.2, Part 1

Lung cancer risk factor in the immigrant population of an industrial area in Poland was examined in a case-control study. Both, relative and summary risks were calculated with adjustment for the following factors: cigarette smoking, alcohol consumption, atmospheric pollution in the place of residence, occupation, education and age. The multivariate logistic analysis indicated that cigarette smoking was a dominant risk factor. In addition, the following factors were confirmed to be significant lung cancer risk factors in the immigrant population of Upper Silesia (Poland): residence in the area of the greatest ecotoxins' concentration; work as toolmakers or manual laborers and seemingly, as coal-miners; lack of university or secondary education, and vodka consumption.

4

Flow cytometric analysis of CD133- and EpCAM-positive cells in the peripheral blood of patients with lung cancer

100%

Skirecki T., Hoser G., Kawiak J., Dziedzic D., Domagala-Kulawik J.

Archivum Immunologiae et Therapiae Experimentalis

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2014

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tom 62

|

nr 1

5

Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik

Effect of selenium on large intestine and lung cancer in humans - part II

100%

Sygit K., Sieja K., Sygit M.

Health Problems of Civilization

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2018

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tom 12

|

nr 3

Background. Persistently high incidence of ‘diseases of affluence’ (including cancer) motivates numerous research teams to look for causes of morbidity, as well as to search for preventive methods and effective therapeutic measures. The paper aims to present the literature on effects of selenium (Se) on prevention of gastrointestinal and lung cancer. Material and methods. Based on national and international literature, the paper presents information on the role of selenium (Se) in prevention of cancer – with special consideration given to gastrointestinal and lung cancer. Results. The results of national and international research show the importance of selenium in prevention and treatment of cancerous diseases, including digestive tract cancer and lung cancer. Numerous studies have shown that the risk of cancer for people with low selenium levels is twice as high as for people with high levels of selenium in blood serum. The most prominent relationship between low selenium level in serum and cancer is observed in gastrointestinal cancer, lung cancer, breast cancer in women, and prostate cancer. Conclusions. Many clinical and experimental studies carried out nationally and internationally gathered evidence which indicate the vital role played by selenium in prevention and treatment of diseases – especially of cancer. It should be emphasised that the intake of selenium in amounts necessary for proper functioning - given numerous deficiencies (first in the soil, then in food products coming from selenium-deficient soil) – is merely the first step, as it has already been proven in numerous publications that carbohydrates (especially simple sugars, sweets, cakes, etc.) ‘destroy’ selenium in the human body.

6

Evaluation of fluorescence-based methods for total vs. amplifiable DNA quantification in plasma of lung cancer patients

100%

Szpechcinski A., Struniawski R., Zaleska J., Chabowski M., Orlowski T., Roszkowski K., Chorostowska-Wynimko J.

Journal of Physiology and Pharmacology. Supplement

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2008

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tom 59

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nr 6

675-681

7

Epac1 is involved in cell cycle progression in lung cancer through PKC and Cx43 regulation

100%

Sun Q., Wang D., Ai G., Tian L., Zhao L., Chen R., Wang K., Guo D., Yao Y., Liu W., Kong X., Chen X., Zhang Y.

Folia Histochemica et Cytobiologica

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2018

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tom 56

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nr 1

8

Impact of preoperative chemotherapy and-or antimicrobial prophylaxis on dynamics of nasopharyngeal microflora in patients with lung cancer during short-term hospitalization

100%

Malm A., Korona-Glowniak I., Kasprzycka A., Rybojad P., Gorniewski G., Furmanik F.

Bulletin of the Veterinary Institute in Puławy. Supplement

|

2002

9

Dendritic cells in peripheral blood of patients with breast and lung cancer - a pilot study

100%

Wojas K., Tabarkiewicz J., Jankiewicz M., Rolinski J.

Folia Histochemica et Cytobiologica

|

2004

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tom 42

|

nr 1

10

Survival of the patient with the small-cell lung cancer and the state of his immunological response. Short report

100%

Krawczyk P., Mackiewicz B., Chocholska S., Milanowski J.

Bulletin of the Veterinary Institute in Puławy. Supplement

|

2002

11

Is the lung cancer among the hereditary malignancies?

100%

Krawczyk P., Michnar M., Kieszko R., Krol A., Wojcik M., Chocholska S., Milanowski J.

Bulletin of the Veterinary Institute in Puławy. Supplement

|

2002

12

Gemcitabine affects the detection of deoxyribonucleotides with a DNA polymerase elongation assay

100%

Van Moorsel C. J. A., Smid K., Pinedo H. M., Peters G. J.

Cellular and Molecular Biology Letters

|

1999

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tom 04

|

nr 3

13

Prognostic significance of epidermal growth factor receptor in surgically treated squamous cell lung cancer patients

100%

Niemiec J., Kolodziejski L., Dyczek S., Gasinska A.

Folia Histochemica et Cytobiologica

|

2004

|

tom 42

|

nr 2

14

Silencing of the type 1 insulin-like growth factor receptor increases the sensitivity to apoptosis and inhibits invasion in human lung adenocarcinoma A549 cells

84%

Ma Z., Dong A., Kong M., Qian J.

Cellular and Molecular Biology Letters

|

2007

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tom 12

|

nr 4

556-572

The type 1 insulin-like growth factor receptor (IGF-1R), which is over-expressed or activated in many human cancers, including lung cancer, mediates cancer cell proliferation and metastasis. Several studies indicate that blocking IGF-1R expression can inhibit tumor cell proliferation and metastasis. In this study, inhibition of the endogenous IGF-1R by recombinant adenoviruses encoding short hairpin RNAs against IGF-1R was found to significantly suppress IGF-1R expression, arrest the cell cycle, enhance the apoptotic response, and inhibit proliferation, adhesion, invasion and migration in A549 cells. Moreover, silencing IGF-1R decreases the expression of invasive-related genes including matrix metalloproteinase-2 (MMP-2), MMP-9, and urokinase-plasminogen activator (u-PA), and the phosphorylation of Akt and ERK1/2. These results suggest that the silencing of IGF-1R has the potential to be an effective cancer gene therapy strategy for human lung cancer.

15

The antiproliferative action of [D-Arg1, D-Phe5, D-Trp7,9, Leu11] substance P analogue antagonist against small cell- and non-small-cell lung cancer cells could be due to the pharmacological profile of its tachykinin receptor antagonist

84%

Munoz M., Recio S., Rosso M., Redondo M., Covenas R.

Journal of Physiology and Pharmacology

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2015

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tom 66

|

nr 3

16

Phenotype of dendritic cells generated in the presence of non-small cell lung cancer antigens - preliminary report

84%

Jankowska O., Krawczyk P., Wojas-Krawczyk K., Sagan D., Milanowski J., Rolinski J.

Folia Histochemica et Cytobiologica

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2008

|

tom 46

|

nr 4

465-470

17

Can CYP1A1 siRNA be an effective treatment for lung cancer?

84%

Mohammed K., Shervington A.

Cellular and Molecular Biology Letters

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2008

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tom 13

|

nr 2

240-249

Abstract: Previously, we identified a novel correlation between the upregulated expression of telomerase (hTERT) and cytochrome P450 1A1 (CYP1A1) in A549 human lung cancer cell line. The expression correlation was confirmed by silencing CYP1A1 expression using siRNA technology and observing a silencing of hTERT transcription. Furthermore, silencing CYP1A1 and subsequently downregulating hTERT resulted in the reduction of cancer cell viability by more than 40%, which appeared as early as 24 hours after the treatment. The concomitant downregulation of CYP1A1 and hTERT resulted in rapid cell death. This finding can be further exploited to develop new molecular targets for the treatment of lung cancer.

18

Nutritional assessment of selected patients with cancer

84%

Surwillo A., Wawrzyniak A.

Roczniki Państwowego Zakładu Higieny

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2013

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tom 64

|

nr 3

Background. It is recognised that both nutritional status and an improper diet have significant effects on weakening the outcomes of treatment in cancer patients. As a result, a lowered response to therapy and an increase in untoward side effects is often observed leading to a deteriorating quality of life. The role of an adequately balanced diet is thus regarded as being vital in supporting recovery. Objective. To assess the dietary consumption of calories, macro-elements and selected vitamins and minerals for subjects diagnosed with cancers of the breast, lungs and bones or soft tissue. Material and Methods. A survey was performed on 100 subjects diagnosed with various tumours between the September and December months of 2011 consisting of 34 with breast cancer, 33 lung cancer and 33 with bone or soft tissue cancer. The questionnaire was devised in-house, which included a three day dietary record. Results. The average daily calorific intake was found to be inadequate at 1608 kcal. In addition, abnormal proportions of energy derived from macro-elements was seen, where the contributions made by fats and proteins were somewhat high at respectively 35.1% and 16.5%, but too low in the case of carbohydrates at 52.1%. Up to 78% subjects had insufficient protein intakes, 88% showed deficiencies in consuming carbohydrates, as were 89% for fibre, 85% vitamin C, 99% calcium, 98% magnesium and 81% for iron. Conclusions. Many dietary shortcomings were observed in the studied subjects. There is therefore a need to educate persons suffering from cancer to adopt an adequate and balanced diet as means of providing vital support for treatment to be more effective.

19

Prognostic significance of DAPK and RASSF1A promoter hypermethylation in non-small cell lung cancer [NSCLC]

84%

Niklinska W., Naumnik W., Sulewska A., Kozlowski M., Pankiewicz W., Milewski R.

Folia Histochemica et Cytobiologica

|

2009

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tom 47

|

nr 2

275-280

20

Immunoexpression of P16INK4a, Rb and TP53 proteins in bronchiolar columnar cell dysplasia [BCCD] in lungs resected due to primary non-small cell lung cancer

84%

Pankiewicz W., Sulewska A., Niklinska W., Naumnik W., Laudanski J., Niklinski J., Chyczewski L.

Folia Histochemica et Cytobiologica

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2008

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tom 46

|

nr 1

89-96

Ograniczanie wyników

The expression of GST isoenzymes and p53 in non-small cell lung cancer

Primary pulmonary adenocarcinoma in roe deer - a case report

The influence of selected environmental factors on lung cancer incidence in immigrant population of industrial areas

Flow cytometric analysis of CD133- and EpCAM-positive cells in the peripheral blood of patients with lung cancer

Effect of selenium on large intestine and lung cancer in humans - part II

Evaluation of fluorescence-based methods for total vs. amplifiable DNA quantification in plasma of lung cancer patients

Epac1 is involved in cell cycle progression in lung cancer through PKC and Cx43 regulation

Impact of preoperative chemotherapy and-or antimicrobial prophylaxis on dynamics of nasopharyngeal microflora in patients with lung cancer during short-term hospitalization

Dendritic cells in peripheral blood of patients with breast and lung cancer - a pilot study