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1

The influence of compounds of tin on the dynamic properties of liposome membranes

100%
Man D., Podolak M., Engel G.
Cellular and Molecular Biology Letters
|
2005
|
tom 10
|
nr Suppl.
2

The effect of selected ammonium salts on dynamic properties of liposome membranes

100%
Podolak M., Man D., Przestalski S., Witek S.
Biophysics of Membrane Transport
|
1994
|
tom 12
|
nr 2
3
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Antioxidative effect of plant extracts and flavones on liposome and erythrocyte membranes

88%
Gabrielska J., Korzeniowska M., Wojdylo A.
Polish Journal of Food and Nutrition Sciences
|
2007
|
tom 57
|
nr 4[A]
145-150
The paper describes the use of liposomes and erythrocytes membrane as a real membrane models to evaluate the potential benefits of several plants extracts and two flavones in relation to lipid peroxidation. The antioxidant behaviour of the plant extracts from pine (Pinus silvestris L), hawthorn (Crataegus oxyacantha L, two extracts: from hawthorn’s leaves-l and bark-b), evening primrose (Oenothena paradoxa Hudziok – three extracts differ in procyanidins content P1, P2 and P3) and rosemary (Rosmarinus officinalis, as a standard for extracts) and flavones of baicalin and rutin have been studied. The results obtained showed that the studied extracts exhibited differentiated, dose-dependent antioxidant activity against phospatidylcholine liposomes (rosemary>pine≈hawthorn-l>hawthorn-b≈P1≈P2≈P3; statistically significant differences were observed between the extracts at p≤0.05) and erythrocyte membranes (rosemary≥hawthorn-b≈hawthorn-l>P1≈pine>P2≈P3) when the oxidation was induced by UV-C radiation. They also reduce the oxidation of liposomes and erythrocyte membrane when its oxidation was induced by 2,2’-azobis(2-amidinopropane) dihydrochloride (pine≥P1≈P2≈rosemary≈P3 in the case of liposomes and rosemary>> pine≥P1≈P2≥P3 in a case of erythrocyte). Moreover, the results of the study show that baicalin is characterised by high inhibition ability towards liposome PC peroxidation, as well as towards erythrocyte ghosts, when oxidation was initiated by UV radiation. However, at the same experimental conditions, the inhibitory capacity of rutin was about 7-8 times weaker. The presence of cholesterol in liposome membrane decreased the level of membrane peroxidation but do not influenced on the antioxidant activity of hawthorn extract.
4

The influence of tin compounds on the dynamic properties of liposome membranes: a study the ESR method

88%
Man D., Podolak M., Engel G.
Cellular and Molecular Biology Letters
|
2006
|
tom 11
|
nr 1
The influence of organic and inorganic compounds of tin on the dynamic properties of liposome membranes obtained in the process of dipalmitoylphosphatidylcholine (DPPC) sonication in distilled water was investigated. This was carried out by means of the spin ESR probe method. The probes were selected in such a way as to penetrate different areas of the membrane (a TEMPO probe, 5-DOXYL stearic acid, 16-DOXYL stearic acid). Four compounds of tin were chosen: three organic ones, (CH3)4Sn, (C2H5)4Sn and (C3H7)3SnCl, and one inorganic one, SnCl2. The investigated compounds were added to a liposome dispersion, which was prepared prior to that. The concentration of the admixture was changed within the values from 0 to 10%-mole in proportion to DPPC. The studies indicated that the chlorides of tin display the highest activity in their interaction with liposome membranes. Since these compounds have ionic form in a water solution, the obtained result can mean that this form of admixture has a considerable influence on its activity. Furthermore, it was found that there is a slightly stronger influence of tin compounds with a longer hydrocarbon chain on changes in the probes’ spectroscopic parameters.
5

Interaction of hydrophilic ammonium salt with the surface of liposome membranes

75%
Podolak M., Man D., Przestalski S.
Biophysics of Membrane Transport
|
1994
|
tom 12
|
nr 2
6

The effect of amphiphilic biocydes contained in a medium on liposome membrane fluidity

75%
Podolak M., Waga S., Przestalski S.
Polish Journal of Environmental Studies
|
1994
|
tom 03
|
nr 2
It was found that quaternary ammonium salt derivatives of glycine ester (GE) admixtures induced increased fluidity of egg yolk lecithin (EYL) liposome membranes (L). The increase depended on chain-lengths of the GEs added and on their concentrations. A maximum fluidity was observed with the 12-carbon atom compound. From considerations concerning the electrostatic interactions in the hydrophilic layer of the liposome mebranes it follows that GEs at low concentrations can induce an increase of binding energy of the layer, while at hihger concentrations the opposite effect can occur.
7

Regulation effect of amphiphilic anionic compounds on calcium ion desorption process from lecithin liposome membranes modified by tripropyltin and tripropyllead compounds

63%
Kral T. E., Kuczera J., Przestalski S.
Cellular and Molecular Biology Letters
|
1999
|
tom 04
|
nr 2
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