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The incidence of vascular injury has increased worldwide. In an attempt to quantitate the specific arteries most commonly involved in the extremities, we reviewed 75 patients with extremity trauma who were evaluated with angiography (DSA, digital subtraction angiography). The majority of these injuries were related to motor vehicle accidents (93.3%). The mean age of these patients was 28.16 ± 11.14 years, 94.7% of these patients being male. The ratio of upper to lower extremity arterial trauma was 12 to 86. A total of 99 arterial injuries were detected angiographically. Simultaneous injuries to two and three extremity arteries were identified in 13.3% and 9.3% of patients respectively. The most common arteries injured were the anterior tibial, femoral, peroneal, and popliteal arteries. Associated fractures were present in 86.7% of patients. These data may prove useful to the clinician who evaluates post-traumatic injuries of the extremities.
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Vascular-endothelial growth factor [VEGF] in patients with peripheral ischemia

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Vascular endothelial growth factor (VEGF) is a key cytokine responsible for the spontaneous new blood vessel formation in the course of peripheral ischemia. It has repeatedly been observed in patients with critical leg ischemia that their clinical status does not reflect any effective local neovascularization processes as well as VEGF system up-regulation. Therefore, the aim of present study was to compare the proangiogenic status, assessed as the serum VEGF concentration, in patients with mild, moderate, and severe peripheral ischemia and to analyze to what extend it is influenced by the therapy applied. Serum VEGF level was evaluated by ELISA method in 31 patients with peripheral ischemia at different time points throughout the treatment. On Day 0 (before treatment), Day 2, and Day 7, VEGF concentration was significantly higher in subjects with critical leg ischemia (Group I) than in other groups (P<0.001). In Group I, VEGF decline was reported on Day 30 following radical surgery, while in a group of moderate disease treated by revascularization surgery a significant increase in serum VEGF concentration was observed (Day 7 and Day 30) (P=0.02). Serum cytokine level in the patients with mild ischemia (Group III) on pharmacotherapy was stable throughout the observation period. Interestingly, the increase in VEGF levels throughout the study period from Day 0 to Day 30 was significantly greater in unsuccessfully treated patients compared with subjects who positively responded to therapy or did not show any response at all. We conclude that mechanisms other than hypoxia might drive the observed up-regulation of VEGF production in peripheral ischemia.
The vasospastic diseases and chronic pain related to lower limb have been successfully treated by surgical ablation of lumbar sympathetic trunk for last 80 years. Precise knowledge of anatomy of lumbar sympathetic trunk and its adjoining structures is mandatory for safe and uncomplicated lumbar and spinal surgeries. We aim to study the detailed anatomy of entry and exit of lumbar sympathetic trunk, the number, dimensions and location of lumbar ganglia in relation to lumbar vertebra. Thorough dissection was carried out in 30 formalin embalmed cadavers available in the Department of Anatomy, Pravara Institute of Medical Sciences (PIMS), Rural Medical College (RMC), Loni, Maharashtra. A total of 238 ganglia were observed in 60 lumbar sympathetic trunks. The sympathetic trunk traversed dorsal to the crus of diaphragm in 72.6% and in 13.3% it entered dorsal to the medial arcuate ligament. The most common site of the location of lumbar ganglia was in relation to the second lumbar vertebra, sometimes extending up to the L2–L3 vertebral disc. There was a medial shift of sympathetic trunk in lumbar region and it coursed over sacral promontory to reach the pelvic region in 96% of specimens. These variations should be kept in mind in order to prevent hazardous complications like accidental avulsion of first lumbar ganglia and genitofemoral neuritis. (Folia Morphol 2013; 72, 3: 217–222)
Introduction. The authors attempt to examine whether functional differences between the legs in soccer players are similar in different motor tests, and whether possible weaker laterality in soccer players could be the effect of the higher fitness level of their left legs, or the lower fitness level of their right legs. Aim of Study. The aim of the study was to determine the scope of differences between the results of motor coordination tests performed with the right leg and the left leg by boys playing soccer and non-training controls. Materials and Methods. 52 soccer training boys and 25 non-training controls volunteered to participate in the experiment. Motor coordination tests of the left and the right legs were performed by participants in order to assess static balance, rate of movements, dynamic endurance, and kinesthetic differentiation. Results. The greatest differences between the training and non-training boys were found in dynamic endurance (left leg, p < 0.001; right leg, p < 0.01). Coaches’ high assessments of players were based on good results of the balance test of the left leg. The differences between the left and the right legs were smaller in the soccer players than in non-training boys, particularly when the results of the left legs were better. Conclusions. In both groups under study the functional asymmetry between the right and the left legs in the static balance and dynamic endurance tests exceeded 20%, which may contribute to possible sport injuries. The soccer players’ static balance test results indicate the presence of training-induced bilateral transfer of balance ability of the legs.
The influence of sex on bone mineral density (BMD) and the bone mineral content (BMC) have been analysed in selected bones of the thoracic and pelvic limbs of African ostriches. The examination was conducted with the use of a densitometer, using the technology of affinited beam of X-ray and the programme for animal research. It was shown that the analysed bones of ostrich skeleton differed significantly regarding the BMD and BMC. Significantly higher values of both parameters were recorded in case of the bones of the pelvic limb in comparison with the bones of the thoracic limb. A central part of the shaft of the tibio-tarsal bone and its proximal end (the pelvic limb) were characterised by the highest values for both BMD and BMC, whereas for the ulnar and radial bones (the thoracic limb) the lowest values were obtained. The study also demonstrated that males showed a significantly higher BMD and BMC values than females referring to the pelvic bones, i.e. the tibio-tarsal bone. For further study aiming at monitoring changes in BMD and BMC during the growth and development of ostriches from hatching till the 14th month of life, the use of densitometer intravitally is recommended.
Scientific literature and museum exhibits are full of explicit and implicit claims about the possible postures and motion ranges of dinosaurs. For the example of the prosauropod Plateosaurus engelhardti I assessed the motion range of limbs and vertebral column in a CAD program using a 3D virtual skeletal mount. The range of motion of the forelimb is very limited, allowing the grasping of objects placed directly ventrally and ventrolaterally of the anterior torso. The manus is adapted for grasping. The powerful fore limb can barely reach in front of the shoulder, making a quadrupedal walking cycle impractical. Only a digitigrade pose of the pes with a steeply held metatarsus is feasible, and the morphology of the stylopodium and zeugopodium indicates a slightly flexed limb posture. Hind limb protraction and retraction are limited by the pelvic architecture. The neck has significant mobility both dorsoventrally and laterally, but blocks torsion. The dorsal vertebral column is flexible to a degree similar to the neck, mainly in the anterior half, but blocks torsion totally in the anterior and posterior thirds. The anterior dorsals are similar in shape to the posterior cervicals and significantly increase the motion range of the neck. The tail is highly flexible due to its large number of elements, showing more lateral than dorsoventral mobility. These results are compared to reconstruction drawings and museum skeletal mounts, highlighting a pattern of errors specific to certain widely used reconstruction methods.
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