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1

Studies on Trichinella spiralis infection in rats exposed to propionibacterium granulosum by intraperitoneal injection

100%
Moskwa B., Polec W.
Acta Parasitologica
|
1993
|
tom 38
|
nr 4
One month old male Wistar rats were infected with 4,000 T. spiralis muscle larvae and exposed to intraperitoneal challenge with a lyophilized cell wall extract of Propionibacterium granulosum. The animals were arranged in groups which included naive controls, single and concurrent treatment. The latter comprised several groups differing only in the interval between infection with T. spiralis and administration of the bacterial extract. The intensity of infection was assessed during the intestinal (5 DAI, 10 DAI) and muscle (42 DAI) phases of infection, fecundity indices were calculated and changes in the relative concentration of peripheral blood leucocytes, erythrocytes and haemoglobin levels were monitored. No changes in erythrocyte concentration were detected in groups treated with the immunomodulator and infected with T. spiralis, but increased leucocyte counts, haematocrit and haemoglobin levels depended on the time of treatment in relation to infection and day on which the parameters were monitored. All rats treated with the bacterial extract had lower adult worm counts but harboured worms with enhanced fecundity relative to the control group. The intensity of the muscle phase was lower only in those groups treated with the bacterial extract after nematode infection.
2

Histological changes in mouse thymus after intraperitoneal injection of Robinia pseudoacacia L. (RpA) lectin

86%
Pierscinski A., Zaremba S., Banach M.
Acta Biologica Cracoviensia. Series Zoologia
|
1989
|
tom 31
3
Content available remote

Effects of peripheral or central GLP-1 receptor blockade on leptin-induced suppression of appetite

72%
Nowak A., Bojanowska E.
Journal of Physiology and Pharmacology
|
2008
|
tom 59
|
nr 3
501-510
Leptin and glucagon-like peptide-1 (GLP-1) were proved to act in concert to control the activity of feeding centres. Since leptin receptor was identified in the gut endocrine L cells and neurons producing GLP-1, we have checked whether GLP-1 mediates the effects of leptin on feeding and drinking behaviour. To this aim, an intraperitoneal or intracerebroventricular injection of exendin (9 - 39), a GLP-1 antagonist, (50 or 10 µg per rat, respectively) followed by leptin (100 or 5 µg per rat, respectively) was made and 24-hour food intake and body weight changes were measured. Previous injection of exendin (9 - 39) completely abolished the suppressory effect of peripheral leptin on food intake and body weight gain. Moreover, exendin (9 - 39) significantly attenuated the effect of intracerebroventricular leptin on food but not water consumption. It is concluded that intact GLP-1 signalling is necessary to mediate the effect of leptin on food intake in the rat. Conversely, leptin seems to affect the thirst center function independently of GLP-1. Also, these findings produce further evidence for close interactions between long- and short-term factors regulating the activity of feeding centres.
4

The role of the BCG dose and the mouse strain in the inhibition of development of neoplasms susceptible and nonsusceptible to the action of natural cytotoxic cells

72%
Skorski T.
Folia Histochemica et Cytobiologica
|
1985
|
tom 23
|
nr 1-2
5

Paracetamol (acetaminophen) decreases hydrogen sulfide tissue concentration in brain but increases it in the heart, liver and kidney in mice

58%
Wilinski B., Wilinski J., Somogyi E., Goralska M., Piotrowska J.
Folia Biologica
|
2011
|
tom 59
|
nr 1-2
6

Influence of dimerized lysozyme (KLP-602) on the immune responses induced by furogen vaccine in rainbow trout (Oncorhynchus mykiss)

58%
Siwicki A. K., Klein P., Kazun K., Morand M., Glabski E., Trapkowska S.
Electronic Journal of Polish Agricultural Universities. Series Veterinary Medicine
|
2002
|
tom 05
|
nr 2
7

Interleukin-6 is not essential for bone turnover in hypothyroid mice

58%
Mysliwiec J., Zbucki R., Winnicka M. M., Sawicki B., Nikolajuk A., Kaminski K., Mysliwiec P., Musial W., Bondyra Z., Walecki J., Gorska M.
Folia Histochemica et Cytobiologica
|
2007
|
tom 45
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nr 4
387-392
8

Induction of chronic subclinical systemic inflammation in Sprague–Dawley rats stimulated by intermittent bolus injection of lipopolysaccharide

58%
Ranneh Y., Akim A. M., Hamid H. A., Khazaai H., Mokhtarrudin N., Fadel A., Albujja M. H. K.
Archivum Immunologiae et Therapiae Experimentalis
|
2019
|
tom 67
|
nr 6
9

Injection of Propionibacterium granulosum affects ATP level in lymphatic organs on rats inoculated with Trichinella spiralis

51%
Moskwa B., Polec W.
Bulletin of the Polish Academy of Sciences. Biological Sciences
|
1992
|
tom 40
|
nr 4
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