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Pulmonary lymphangitic carcinomatosis in the course of gastric cancer - Case report

100%
Witczak A., Prystupa A., Zamecka M. O., Bilan A., Krupski W., Mosiewicz J.
Journal of Pre-Clinical and Clinical Research
|
2014
|
tom 08
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nr 2
Pulmonary lymphangitic carcinomatosis is a special type of diffuse metastasis of carcinoma in the lymphatic vessels of the lungs. Lymphangitic carcinomatosis is commonly observed in malignancies of the breast, lung, pancreas, colon and cervix as a strong marker for poor prognosis. Presenting with common respiratory symptoms, it may be easily misdiagnosed as other pulmonary interstitial diseases. Pulmonary lymphangitic carcinomatosis is a rare manifestation of metastatic gastric cancer. The presented case describes a patient with pulmonary lymphangitic carcinomatosis in the course of stomach cancer. The primary diagnosis was established based on the exclusion of other interstitial lung diseases, with the use of imaging techniques as well as biochemical, microbiological and cytological findings. The patient’s general condition was very severe, rendering him bedridden and therefore not eligible for any treatment, including chemotherapy. He died suddenly before final verification of the diagnosis. Pulmonary lymphangitic carcinomatosis should be suspected in patients with advanced gastric cancer, presenting with symptoms and signs of respiratory disease. Imaging techniques are mostly helpful to establish the diagnosis.
2
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Dyspnea and quality of life in patients with pulmonary fibrosis after six weeks of respiratory rehabilitation

75%
Jastrzebski D., Gumola A., Gawlik R., Kozielski J.
Journal of Physiology and Pharmacology. Supplement
|
2006
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tom 57
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nr 4
139-148
The aim of the study was to estimate the level of dyspnea and quality of life in patients with pulmonary fibrosis after 6 weeks' respiratory rehabilitation. The study comprised of 31 patients (F/M-12/19) with interstitial lung diseases (21 with idiopathic interstitial pneumonia, 4 with lung fibrosis due to allergic alveolitis, 4 with lung fibrosis due to collagenosis, 2 with lung fibrosis due to silicosis) who successfully finished the rehabilitation program. Each patient underwent an intensive (every day for 30 min) inpatient pulmonary rehabilitation program of an average length of 4 wk, continued later at home for up to 12 wk. The program consisted of respiratory muscle training and bicycle riding to the limits of the patient's tolerance. Dyspnea (MRC, OCD, BDI and Borg scale) and the quality of live (SF-36, St. George's Respiratory Questionnaire) were assessed at the time of admission and discharge. Rehabilitation caused dyspnea sensation to diminish (Borg scale: 2.97 before vs. 2.19 after). Some domains of the quality of life in SF-36 questionnaire (Role-Physical 40.6 vs. 60.2) and St. George's Respiratory Questionnaire (activity: 52 vs. 45, impact 47 vs. 40 and total 47 vs. 42) also were improved compared with the pre-rehabilitation results. We conclude that 12 weeks of combined inpatient and home-based rehabilitation programme improves the quality of live and sensation of dyspnea in patients with interstitial lung disease, despite changes in pulmonary function tests.
3
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Prognostic risk factors in patients with interstitial lung disease referred for lung transplantation

75%
Jastrzebski D., Kozielski J., Nowak J., Zielinska-Les I., Ziora D., Szulik B., Wojarski J., Zakliczynski M., Zembala M.
Journal of Physiology and Pharmacology. Supplement
|
2005
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tom 56
|
nr 4
107-113
The aim of the study was to identify prognostic factors that would differentiate patients with interstitial lung disease between those with and without a chance to survive until lung transplantation. A retrospective study was performed in patients with interstitial lung disease referred for lung transplantation between September 1999 and April 2005. The analysis included the demographic data, the time from referral to transplantation, the functional tests (FVC, FEV1, FEV1%VC, the PaO2 at rest and after oxygen supplementation via a nasal catheter), the count of NYHA functional classes, the left ventricular ejection fraction (EF), the distance covered during a 6-min walk test, and the pathogens in the respiratory tract. The patients were divided into two groups: Group 1 - lung transplant candidates who survived until the successful procedure and Group 2 - lung transplant candidates who died while on the waiting list. There were statistical differences between the two groups in PaO2 after supplementation (P=0.005), EF (P=0.002), and the 6-min walk distance (P=0.001). It appears that simple functional tests of the cardiorespiratory system may define survival of patients with interstitial lung disease waiting for lung transplantation.
4
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Right ventricular function in patients with severe interstitial lung disease: a tissue Doppler imaging study

75%
Nowak J., Jastrzebski D., Streb W., Rozentryt P., Wojarski J., Greif M., Kozielski J., Polonski L., Zembala M., Kukulski T.
Journal of Physiology and Pharmacology. Supplement
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2008
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tom 59
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nr 6
531-538
5
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Role of bronchoalveolar lavage in the initial diagnosis of smoking-related interstitial lung diseases

75%
Domagala-Kulawik J., Maskey-Warzechowska M., Krenke R., Chazan R.
Journal of Physiology and Pharmacology. Supplement
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2008
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tom 59
|
nr 6
243-251
6
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Upregulation of Th1 cytokine profile in bronchoalveolar lavage fluid of patients with hypersensitivity pneumonitis

63%
Mroz R. M., Korniluk M., Stasiak-Barmuta A., Chyczewska E.
Journal of Physiology and Pharmacology. Supplement
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2008
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tom 59
|
nr 6
499-505
7

The role of leukotrienes in the pathogenesis of systemic sclerosis

63%
Chwiesko-Minarowska S., Kowal K., Bielecki M., Kowal-Bielecka O.
Folia Histochemica et Cytobiologica
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2012
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tom 50
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nr 2
8
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Induced sputum in patients with interstitial lung disease: a non-invasive surrogate for certain parameters in bronchoalveolar lavage fluid

63%
Sobiecka M., Kus J., Demkow U., Filewska M., Jozwik A., Radwan-Rohrenschef P., Chorostowska-Wynimko J.
Journal of Physiology and Pharmacology. Supplement
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2008
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tom 59
|
nr 6
645-657
9
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Angiogenic activity of sera from silicosis and pulmonary Langerhans cell histiocytosis patients in relation to lung function tests

63%
Zielonka T. M., Demkow U., Filewska M., Bialas-Chromiec B., Zycinska K., Radzikowska E., Korzeniewska M., Wardyn K. A., Kus J., Skopinska-Rozewska E.
Journal of Physiology and Pharmacology. Supplement
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2008
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tom 59
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nr 6
781-789
10
Content available remote

Left ventricular dysfunction in patients with interstitial lung diseases referred for lung transplantation

63%
Jastrzebski D., Nowak J., Ziora D., Wojarski J., Czyzewski D., Kozielski J., Polonski L., Zembala M.
Journal of Physiology and Pharmacology. Supplement
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2007
|
tom 58
|
nr 5
11

Concentration of surfactant protein D, Clara cell protein CC-16 and IL-10 bronchoalveolar lavage [BAL] in patients with sarcoidosis, hypersensitivity pneumonitis and idiopathic pulmonary fibrosis

51%
Kucejko W., Chyczewska E., Naumnik W., Ossolinska M.
Folia Histochemica et Cytobiologica
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2009
|
tom 47
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nr 2
225-230
12
Content available remote

TNFalpha and INFgamma inducing capacity of sera from patients with interstitial lung disease in relation to its angiogenesis activity

51%
Zielonka T. M., Demkow U., Puscinska E., Golian-Geremek A., Filewska M., Zycinska K., Bialas-Chromiec B., Wardyn K. A., Skopinska-Rozewska E.
Journal of Physiology and Pharmacology. Supplement
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2007
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tom 58
|
nr 5
13

Enhanced expression of Fas Ligand (FasL) in the lower airways of patients with fibrotic interstitial lung diseases (ILDs)

51%
Kopinski P., Balicka-Slusarczyk B., Dyczek A., Szpechcinski A., Przybylski G., Jarzemska A., Wandtke T., Jankowski M., Iwaniec T., Chorostowska-Wynimko J.
Folia Histochemica et Cytobiologica
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2011
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tom 49
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nr 4
14

Expression of insulin-like growth factor-I [IGF-I] in alveolar macrophages and lymphocytes obtained by bronchoalveolar lavage [BAL] in interstitial lung diseases [ILD]. Assessment of IGF-I as a potential local mitogen and antiapoptotic cytokine

51%
Kopinski P., Sladek K., Szczeklik J., Soja J., Szlubowski A., Balicka-Slusarczyk B., Lackowska B., Plato M., Szpechcinski A.
Folia Histochemica et Cytobiologica
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2006
|
tom 44
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nr 4
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