Wyniki wyszukiwania

1

Increased levels of interleukin-12 and interleukin-18 in bronchoalveolar lavage fluid of patients with pulmonary sarcoidosis

100%

Mroz R. M., Korniluk M., Stasiak-Barmuta A., Chyczewska E.

Journal of Physiology and Pharmacology. Supplement

|

2008

|

tom 59

|

nr 6

507-513

2

Antitumor effects of recombinant antivascular protein ABRaA-VEGF121 combined with IL-12 gene therapy

100%

Ciomber A., Smagur A., Mitrus I., Cichon T., Smolarczyk R., Sochanik A., Szala S., Jarosz M.

Archivum Immunologiae et Therapiae Experimentalis

|

2014

|

tom 62

|

nr 2

3

Cytokine-based immunotherapy of allergic disease

100%

Lewkowich I. P., HayGlass K. T.

Archivum Immunologiae et Therapiae Experimentalis

|

2001

|

tom 49

|

nr 4

4

The effect of Naja naja oxiana snake venom against Leishmania tropica confirmed by advanced assays

84%

Sharifi I., Tabatabaie F., Nikpour S., Mostafavi M., Oliaee R. T., Sharifi F., Babaei Z., Jafari E., Salarkia E., Shahbazzadeh D.

Acta Parasitologica

|

2021

|

tom 66

|

nr 2

5

Upregulation of Th1 cytokine profile in bronchoalveolar lavage fluid of patients with hypersensitivity pneumonitis

84%

Mroz R. M., Korniluk M., Stasiak-Barmuta A., Chyczewska E.

Journal of Physiology and Pharmacology. Supplement

|

2008

|

tom 59

|

nr 6

499-505

6

Increased level of soluble adenosine deaminase in bone marrow of visceral leishmaniasis patients: an inverse relation with parasite load

84%

Rai A. K., Kumar P., Saini S., Thakur C. P., Seth T., Dipendra D. K.

Acta Parasitologica

|

2016

|

tom 61

|

nr 3

7

Interferon gamma production in the course of Mycobacterium tuberculosis infection

84%

Winek J., Rowinska-Zakrzewska E., Demkow U., Szopinski J., Szolkowska M., Filewska M., Jagodzinski J., Roszkowski-Sliz K.

Journal of Physiology and Pharmacology. Supplement

|

2008

|

tom 59

|

nr 6

751-759

8

Tumor-resident CD8plus T-cell: the critical catalyst in Il-12-mediated reversal of tumor immune suppression

84%

Egilmez N. K., Kilinc M. O.

Archivum Immunologiae et Therapiae Experimentalis

|

2010

|

tom 58

|

nr 6

399-405

9

Current status of M1 and M2 macrophages pathway as drug targets for inflammatory bowel disease

84%

Seyedizade S. S., Afshari K., Bayat S., Rahmani F., Momtaz S., Rezaei N., Abdolghaffari A. H.

Archivum Immunologiae et Therapiae Experimentalis

|

2020

|

tom 68

|

nr 2

10

Combined tumor cell-based vaccination and interleukin-12 gene therapy polarizes the tumor microenvironment in mice

84%

Jarosz-Biej M., Smolarczyk R., Cichon T., Kulach N., Czapla J., Matuszczak S., Szala S.

Archivum Immunologiae et Therapiae Experimentalis

|

2015

|

tom 63

|

nr 6

11

Immunocytochemical analysis of the tissue location of cytokines [IL-2 and IL-12] in neuroendocrine lung cancer

84%

Kasprzak A., Przewozna M., Zabel M., Pankowski J., Surdyk-Zasada J.

Folia Morphologica

|

2003

|

tom 62

|

nr 3

301-303

The study aimed at immunocytochemical evaluation of the cellular expression of two cytokines, IL-2 and IL-12 in lung carcinoids (n = 10), following the earlier demonstration of two markers of endocrine tumours (chromogranin A and NSE — neuron-specific enolase). In the immunocytochemical studies the classical avidin-biotinylated peroxidase (ABC) technique was used. Results of the tests were semiquantitatively appraised employing the IRS scale. In 9/10 cases intense reaction (score: 6–12 points) was noted for both lung neuroendocrine markers. In all cases of carcinoma co-expression of IL-2 and IL-12 was demonstrated in cells of the tumours. The cytokines showed a cytoplasmic localisation of mean (score: 3–4 points) or high (score: 6–12 points) intensity of reaction. Our studies point to a possible role of the two cytokines in the proliferation of lung neuroendocrine carcinomas but more detailed analysis is required on a broader material.

12

Combined delivery of an antiangiogenic protein [angiostatin] and an immunomodulatory gene [interleukin-12] in the treatment of murine cancer

84%

Wilczynska U., Kucharska A., Szary J., Szala S.

Acta Biochimica Polonica

|

2001

|

tom 48

|

nr 4

We investigated the feasibility of a novel therapeutic approach to treat neoplastic diseases in mice. This novel strategy consists in delivering a protein (angiostatin) with strong antiangiogenic properties, followed by administration of the interleukin 12 gene that is strongly immunomodulatory and has also some antiangiogenic effects. When angiostatin-mediated antiangiogenic therapy was used in combination with intratumor delivery of the IL-12 gene (a strategy much safer than IL-12 protein administration), this produced a synergistic therapeutic effect.

13

Regulation of innate and adaptive immune responses by the related cytokines IL-12, IL-23, and IL-27

84%

Beadling C., Slifka M. K.

Archivum Immunologiae et Therapiae Experimentalis

|

2006

|

tom 54

|

nr 1

14

Combination of IL-12 gene therapy and CTX chemotherapy inhibits growth of primary B16[F10] melanoma tumors in mice

84%

Mitrus I., Delic K., Wrobel N., Missol-Kolka E., Szala S.

Acta Biochimica Polonica

|

2006

|

tom 53

|

nr 2

We investigated suppression of murine B16(F10) melanoma tumor growth following a therapy which involved concomitant administration of cyclophosphamide and plasmid DNA bearing interleukin-12 gene. Since both therapeutic factors display antiangiogenic capabilities, we assumed that their use in blocking the formation of new blood vessels would result in augmented inhibition of tumor growth. This combined therapy regimen indeed resulted in a considerable suppression of tumor growth. We observed a statistically significant extension of treated animals' lifespan. Interestingly, the therapeutic effect was also obtained using a plasmid without an interleukin gene insert. This observation suggests that plasmid DNA, which has been widely applied for treating neoplastic tumors, contains element(s) that elicit immune response in mice.

15

Astronium fraxinifolium Schott exerts leishmanicidal activity by providing a classically polarized profile in infected macrophages

67%

Braga M. A., de Oliveira Rodrigues R., Yaochite J. N. U., Sasahara G. L., Almeida Santos F., Fonseca F. R. M., de Castro Rodrigues N. L., Teixeira M. J., Tavares Calixto Jr J., Moreira Rodrigues A. L., de Morais S. M., Nagao-Dias A. T.

Acta Parasitologica

|

2020

|

tom 65

|

nr 3

16

NK cells prevalence, subsets and function in viral hepatitis C

67%

Zeromski J., Mozer-Lisewska I., Kaczmarek M., Kowala-Piaskowska A., Sikora J.

Archivum Immunologiae et Therapiae Experimentalis

|

2011

|

tom 59

|

nr 6

17

Toll-like receptors’ pathway disturbances are associated with increased susceptibility to infections in humans

67%

Frazao J. B., Errante P. R., Condino-Neto A.

Archivum Immunologiae et Therapiae Experimentalis

|

2013

|

tom 61

|

nr 6

18

D-K6L9 peptide combination with IL-12 inhibits the recurrence of tumors in mice

67%

Cichon T., Smolarczyk R., Matuszczak S., Barczyk M., Jarosz M., Szala S.

Archivum Immunologiae et Therapiae Experimentalis

|

2014

|

tom 62

|

nr 4

19

Tumor-associated macrophages as target for antitumor therapy

67%

Sawa-Wejksza K., Kandefer-Szerszen M.

Archivum Immunologiae et Therapiae Experimentalis

|

2018

|

tom 66

|

nr 2

20

Gamma delta T cell positively regulate contact sensitivity (CS) reaction via modulation of INF-gamma, IL-12 and TNF-alpha production

67%

Strzępa A., Majewska-Szczepanik M., Szczepanik M.

Folia Biologica

|

2013

|

tom 61

|

nr 3-4

Ograniczanie wyników

Increased levels of interleukin-12 and interleukin-18 in bronchoalveolar lavage fluid of patients with pulmonary sarcoidosis

Antitumor effects of recombinant antivascular protein ABRaA-VEGF121 combined with IL-12 gene therapy

Cytokine-based immunotherapy of allergic disease

The effect of Naja naja oxiana snake venom against Leishmania tropica confirmed by advanced assays

Upregulation of Th1 cytokine profile in bronchoalveolar lavage fluid of patients with hypersensitivity pneumonitis

Increased level of soluble adenosine deaminase in bone marrow of visceral leishmaniasis patients: an inverse relation with parasite load

Interferon gamma production in the course of Mycobacterium tuberculosis infection

Tumor-resident CD8plus T-cell: the critical catalyst in Il-12-mediated reversal of tumor immune suppression

Current status of M1 and M2 macrophages pathway as drug targets for inflammatory bowel disease

Combined tumor cell-based vaccination and interleukin-12 gene therapy polarizes the tumor microenvironment in mice

Immunocytochemical analysis of the tissue location of cytokines [IL-2 and IL-12] in neuroendocrine lung cancer

Combined delivery of an antiangiogenic protein [angiostatin] and an immunomodulatory gene [interleukin-12] in the treatment of murine cancer

Regulation of innate and adaptive immune responses by the related cytokines IL-12, IL-23, and IL-27

Combination of IL-12 gene therapy and CTX chemotherapy inhibits growth of primary B16[F10] melanoma tumors in mice

Astronium fraxinifolium Schott exerts leishmanicidal activity by providing a classically polarized profile in infected macrophages

NK cells prevalence, subsets and function in viral hepatitis C

Toll-like receptors’ pathway disturbances are associated with increased susceptibility to infections in humans

D-K6L9 peptide combination with IL-12 inhibits the recurrence of tumors in mice

Tumor-associated macrophages as target for antitumor therapy

Gamma delta T cell positively regulate contact sensitivity (CS) reaction via modulation of INF-gamma, IL-12 and TNF-alpha production