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Background. Rational nutrition of infants and toddlers is essential for their normal growth and development, and for the development of proper nutritional habits. It should be preceded by proper planning. Objective. The aim of the study was to evaluate of the planning and organization of nutrition in nurseries. Material and methods. In the research conducted within the program “Eating healthy, growing healthy” (EHGH), 128 crèches from all over Poland participated. The nurseries were attended by 8182 children under the age of 3. The research was carried out between 2015 and 2016. Data on the organization and quality of nutrition were collected through direct interviews with directors and / or staff responsible for feeding in crèches. In addition, analysis of the decade’s menu of the participating institutions (128 menus) and daily inventory reports (1280 documents) were analyzed. The data were analyzed for the total number and the type (public and non-public) of institution. The program Statistica Version 13.1 was used. Results. Half of the surveyed DCCs planned in the menu whole grains, nearly all of them served fresh vegetables and fruits to the children, and every third added them to every meal. The most common drink during the meal was compote. Access to water between meals was offered to children in majority of the DCCs. The quality of diet was differentiated by the type of nursery: depending on the type (public vs non-public), the differences in salting and sweetening meals have been shown. Public DCCs had a much lower average amount of money allocated per day to feed a child compared to non-public, most of these managed own kitchens and did not employ a dietitian. Despite the higher nutritional rates in non-public crèches, some errors in nutrition planning have been observed. Conclusions. Higher average amount of money allocated per day to feed a child in non-public nurseries did not provide adequate nutrition. There is a need to publish standardized, understandable and practical recommendations in nutrition of children in nurseries. Adopting such recommendations in daily practice in all public and non-public crèches should improve the nutrition of children.
Food is the main source of mineral elements but some are also provided with drinking water and supplements. Juices, for example, are an important source of mineral elements. In infants’ diet minerals are provided mainly by fruit and vegetable purée juices. Infants and young children should be given juices labelled as “special purpose food”. Pasteurised juices are recommended for infants, as they are free of bacteria and toxins, a condition that cannot be completely fulfilled while making juices at home. The aim of the present work was to determine the content of some minerals in fruit and vegetable juices for infants and children under three years of age. The research material consisted of juices, all before their use-by date, purchased in grocer shops in Lublin in January 2006. In total 20 juices were examined, 8 of which were labelled as ‘special purpose food’, 2 were recommended by the National Food and Nutrition Institute and ten juices were labelled as ‘food for young children’. Juices make an important source of minerals in the diet of infants and young children. The most valuable ones are the fruit and vegetable purée juices, as they provide significant amounts of dry mass which includes fibre, minerals and vitamins. Differences in the content of particular mineral elements in juices result primarily from their composition. Although juices for infants and young children should not contain any additives, products without certificates must be treated with caution as it cannot be excluded that some may contain prohibited compounds, e.g. calcium ascorbate or calcium chloride.
Background. Exclusive breastfeeding is the gold standard in infant nutrition. The maternal decision to breastfeed is affected by various factors, including breastfeeding knowledge. Objective. The purpose of this study was the assessment of the breastfeeding knowledge in selected group of mothers of infants under 7 months and its relationship to the exclusivity of breastfeeding. Material and methods. The study was carried out using the CAWI method from Dec 2014 till Feb 2015 among 446 mothers (aged 18-42) of infants under 7 months. The most of women lived in towns >100.000 inhabitants, had an university education and normal pre-pregnancy BMI. Breastfeeding knowledge was estimated using 15 questions (both 6 in general and child-related category and 3 in mother-related category). Results were analysed using multivariate logistic analysis and Chi2 and U-Mann Whitney tests. Results. 57% (group A) of women exclusively breastfeed their infants and 43% (group B) did not. Average mean breastfeeding knowledge test score was 11.9±3.4 points. Higher mean was observed in group A compared with group B (12.9±2.8 vs. 10.6±3.7 points; p≤0.001). Predictors of lower score (<11 points) were professional education, overweight and living in the rural area. Each correct answer to questions in general (OR1.93; 95%CI 1.57-2.37) or in child-related (OR1.33; 95%CI 1.10-1.63) category improved the chance of exclusive breastfeeding. Women from group A had a better score in every question. Conclusion. Breastfeeding education for mothers may improve breastfeeding rates.
Respiratory Syncytial Virus (RSV) is one of the most common causes of lower respiratory tract infections in young children, immunocompromised patients (children and adults), patients with chronic respiratory diseases and elderly people. Reinfections occur throughout the life, but the severity of disease decreased with subsequent infection. The aim of this study was to analyze the frequency of RSV infections in two selected subpopulations: young children (below 5 y.) and adults with chronic respiratory diseases (25–87 y.). Nasopharyngeal swabs (334) collected from October 2008 to March 2010 were examined. The presence of RSV genome was determined by RT-PCR and the presence of RSV antigen by quick immunochromatographic test. Positive results of RT-PCR were found in 45.2% of all swabs: 48.6% samples in 2008; 41.5% in 2009; 50.8% in 2010. The highest frequency of RSV-positive samples was in fall-winter months, but differences in RSV epidemic seasons were found. In the first season (2008–2009) an increased number of RSV infections was observed from November 2008, but in the second season – from January 2010. Generally, the frequency of RSV-positive RT-PCR among children was 53%, among adults 25%. The highest difference was observed in the first three-month period of 2010. RT-PCR positive samples were found in 68.5% of children and 5.9% of adults. However, the RSV antigen was found in 44.4% of samples collected from adults in this period. Our results indicate that the contribution of RSV infections during epidemic season of respiratory tract infections in Poland was really high among children and adults.
Background. Thermal processes and long storage of food lead to reactions between reducing sugars and amino acids, or with ascorbic acid, carbohydrates or polyunsaturated fatty acids. As a result of these reactions, new compounds are created. One of these compounds having an adverse effect on human health is furan. Objective. The aim of this paper was to estimate the infants exposure to furan found in thermally processed jarred food products, as well as characterizing the risk by comparing the exposure to the reference dose (RfD) and calculating margins of exposure. Materials and methods. The material consisted of 301 samples of thermally processed food for infants taken from the Polish market in years 2008 – 2010. The samples included vegetable-meat, vegetables and fruit jarred meals for infants and young children in which the furan levels were analyzed by GC/MS technique. The exposure to furan has been assessed for the 3, 4, 6, 9 ,12 months old infants using different consumption scenarios. Results. The levels of furan ranged from <1 μg/kg (LOQ) to 166.9 μg/kg. The average furan concentration in all samples was 40.2 μg/kg. The estimated exposures, calculated with different nutrition scenarios, were in the range from 0.03 to 3.56 μg/kg bw/day and exceeded in some cases RfD set at level of 1 μg/kg bw/day. Margins of exposure (MOE) achieved values even below 300 for scenarios assuming higher consumption of vegetable and vegetable-meat products. Conclusions. The magnitude of exposure to furan present in ready-to-eat meals among Polish infants is similar to data reported previously in other European countries but slightly higher than indicated in the recent EFSA report. As for some cases the estimated intake exceeds the RfD, and MOE) values are much lower than 10000 indicating a potential health concern, it is necessary to continue monitoring of furan in jarred food and estimate of its intake by infants.
Myotis nattereri born and reared by their mothers in a flight room had a mean birth body mass of 3.4 g and forearm length of 17.00 mm. Infants opened their eyes at 6 days old, and they were no longer always found roosting attached to their mothers after this age. They were fully furred at 7-8 days and began to flap their wings at days. Growth was initially rapid and linear until 20 days of age and then slowed. At 58-60 days, mean body mass was 8.8 g (89% of adult mass) and mean forearm length was 40.55 mm (98% of adult length). Juveniles began to fly at 20 days, at which age their forearm length was 93.4% of mean adult value. Forearm data were best fitted by the logistic growth model (k = 0.18; asymptotic length = 40.79 mm for males) and body mass data by the von Bertalanffy equation (k = 0.10; asymptotic mass = 8.42 g for males). Pre-flight growth and development rates were similar to those in other British vespertilionid bats, but M. nattereri showed very rapid development of foraging ability after they began to fly. Mothers suckled only their own infants and transported flightless young between roost boxes, on average every 5.3 days.
Omówiono problemy zdrowotne spowodowane wadliwym żywieniem niemowląt i dzieci przedszkolnych a także zmiany w rozpowszechnieniu karmienia piersią w Szwecji. Opisano główne nieprawidłowości w żywieniu dzieci przedszkolnych oraz cele oświaty zdrowotnej dla rodziców. Zwrócono uwagę na powiązania między karmieniem sztucznym, dostarczającym dużych ilości białka a hiperinsulinemią u niemowląt do 6 miesiąca życia.
The study objective was to determine plasma concentration of pyrimethamine in 24 infants aged 1–5 months, treated for congenital toxoplasmosis. Pyrimethamine was used in a single daily dose at an amount of 0.35–0.98 mg/kg daily, with sulfadiazine (50–100 mg/kg/day) in divided doses 2–3 times a day, and folinic acid given twice a week (7.5 mg). This regimen was continued for 2–6 months, then Fansidar® was administered. Pyrimethamine concentration in plasma was measured using high-performance liquid chromatography method (HPLC). A total of 70 tests were performed. Concentration of pyrimethamine ranged from 0.01 to 1.2 μg/ml. In 14 children (58 tests) the concentration of pyrimethamine achieved therapeutic value. In 7 patients (8 tests) the concentration was below therapeutic level, and in 3 patients (4 tests) above therapeutic level. In 11/24 (46%) children transient moderate neutropenia was observed. Modification of therapy was necessary in 12 patients. Monitoring of pyrimethamine concentration in plasma improves safety and effectiveness of the therapy and is useful in obtaining correct individual dose of the drug. Neutropenia is the most common side-effect of pyrimethamine observed even when using the recommended dose.
Cartilage-hair hypoplasia (CHH) is a rare autosomal-recessive disorder characterized by short-limbed dwarfism, sparse hair, and immune deficiency. It is caused by mutations in the RMRP gene, which encodes the RNA component of the mitochondrial RNA-processing ribonuclease (RNase MRP). Several mutations have been identified in its promoter region or transcribed sequence. However, homozygous mutations in the promoter region have been only reported in a patient with primary immunodeficiency without other features of CHH. We report on a Thai girl who first presented with chronic diarrhea, recurrent pneumonia, and severe failure to thrive, without apparently disproportionate dwarfism. The diagnosis of CHH was made after the severe wasting was corrected, and disproportionate growth became noticeable. The patient had the typical features of CHH, including sparse hair and metaphyseal abnormalities. The immunologic profiles were consistent with combined immune deficiency. Mutation analysis identified a novel homozygous mutation, g.-19_-25 dupACTACTC, in the promoter region of the RMRP gene. Identification of the mutation enabled us to provide a prenatal diagnosis in the subsequent pregnancy. This patient is the first CHH case with the characteristic features due to the homozygous mutation in the promoter region of the RMRP gene. The finding of severe immunodeficiency supports that promoter mutations markedly disrupt mRNA cleavage function, which causes cell-cycle impairment.
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The determination of the furosine (FUR) indicator of the Maillard reaction in commercial infant formulae (IF), follow-on formulae (FF), human milk (N=10) and raw cow milk (N=7) was performed using high performance liquid chromatography with ultraviolet detection (HPLC/UV). A high FUR content was confirmed that ranged from 1320±102.2 to 1550.9±166.5 mg/100 g protein in infant formulae IF and from 931.9±153.8 to 1156.7±104.5 mg/100 g protein in follow-on formulae FF (human milk – at the average below 6 mg/100 g protein). Such a significant difference between FUR values of commercially available formulas is accounted for imperfection of different technologies of manufacturing IF and FF. In dairy products damage caused by heat treatment could be greater as a result of manufacturing processes and storage conditions. Furosine content was used in order to calculate the concentration of blocked lysine. In infant formulas IF’s the blocked lysine levels were found to range from 19.6 to 34% of total lysine. Taking into consideration harmful for health, toxic products of Mallard reaction, the content of FUR should be labelled. In the Authors’ opinion, the content of furosine tolerance should make compromise between that what is theoretical demanded and that what is practical reached (fresh milk powder for all purposes – about 120 mg FUR/100 g protein, FF of producer C – 930 mg FUR/100 g protein). The authors’ suggestion is that the maximum allowable tolerance of FUR should not exceed 700 mg/100 g protein of IF and FF.
The popularity of seven groups of processed foodstuffs (soups, dinners, pulverized fruits and vegetables, desserts, dairy desserts, juices, teas) for infants and small children aged 4 months up to 3 years, available on the market and comprising a total of 154 products, was investigated in this study. A survey was carried out in the group of 100 individuals. They were mothers and fathers bringing their children to crèche as well as buying analysed products. Among 24 soups vegetable soup with rabbit meat, vegetable soup and vegetable soup with chicken turned out to be most popular, as they were bought by 26%, 25% and 24% parents, respectively. In the group of second courses the most popular included vegetable with rabbit meat (19%), vegetables with lamb and groats (17%) and lamb in vegetable stew (16%). The most popular pulverized fruits and vegetables included apple (32%), apple with blueberries (27%), carrot and apple (26%) and carrot, apple and forest berries (23%). In the group of fruit and cereal desserts mango with banana and passion fruit juice turned out to be the most popular (22%), while among dairy desserts it was vanilla dessert (23%). Out of 30 kinds of juices, parents purchased most frequently carrot and apple juice (52%) and apple juice (37%), while in the group of teas it was fennel tea as well as camomile tea and herbal tea for colds. A total of 33% and 29% parents, respectively, bought the above mentioned teas. Most respondents were of the opinion that the taste of these products was slightly inferior to those prepared at home and the price was too high, but they bought them for their convenience
Seven skulls of newborns and of infants aged 3 weeks to 12 months were studied using computed tomography. Size of the maxillary sinuses was measured. Between 3rd and l2nd week of life the ethmoidal sinus formed small spaces in ethmoidal labyrinth. Maxillary sinus could be noted at the level of lower orbital margin. In newborns, it formed a shallow indentation in the lateral wall of the nasal cavity. The anteroposterior dimension of the sinus was greater- than the two remaining dimensions. Beginning from the 3rd month of life, number of ethmoidal cells increased, maxillary sinuses enlarged and entered the body of the maxilla. Between 6th and l2th month, the mediolateral and the superoinferior dimensions of the sinuses increased. Small air spaces were also seen in the part of sphenoid bone, corresponding to sphenoidal sinueses.
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