Wyniki wyszukiwania

1

Modulatory effect of the Euro-Lupus low-dose intravenous cyclophosphamide regimen on circulating immune cells in systemic lupus erythematosus

100%

Gabcova G., Horak P., Mikulkova Z., Skacelova M., Zehnalova S., Smrzova A., Petrackova A., Mrazek F., Kriegova E.

Archivum Immunologiae et Therapiae Experimentalis

|

2019

|

tom 67

|

nr 6

2

Acquired pericentric inversion of chromosome 9 in acute myeloid leukemia

100%

Udayakumar A. M., Pathare A. V., Dennison D., Raeburn J. A.

Journal of Applied Genetics

|

2009

|

tom 50

|

nr 1

73-76

Pericentric inversion of chromosome 9 involving the qh region is relatively common as a constitutional genetic aberration without any apparent phenotypic consequences. However, it has not been established as an acquired abnormality in cancer. Among the three patients reported so far in the literature with acquired inv(9), only one had acute myeloid leukemia (AML). Here we describe an unique case where both chromosomes 9 presented with an acquired pericentric inversion with breakpoints at 9p 13 and 9q 12 respectively, in a AML patient with aberrant CD7 and CD9 positivity. Additionally, one der(9) also showed short arm deletion at 9p21 to the centromeric region and including the p 16 gene. The constitutional karyotype was normal. This is probably the first report describing an acquired inv(9) involving both chromosomes 9 in AML. The possible significance of this inversion is discussed.

3

The influence of different culture microenvironments on the generation of dendritic cells from non-small-cell lung cancer patients

84%

Krawczyk P., Wojas K., Milanowski J., Rolinski J.

Archivum Immunologiae et Therapiae Experimentalis

|

2007

|

tom 55

|

nr 6

4

Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik

Cellular immune response of pigeons in the conditions of endotoxin fever and pyrogenic tolerance

67%

Dudek K., Bednarek D.

Polish Journal of Veterinary Sciences

|

2011

|

tom 14

|

nr 1

The aim of this study was to investigate changes in selected parameters of cellular immune response in the conditions of endotoxin fever and pyrogenic tolerance in pigeons. On the first day of observation the experimental birds (n=18) were intravenously injected with Escherichia coli LPS at a dose of 10 μg/kg b.w., while the control animals (n=6) received apyrogenic physiological saline also in the form of injection. On the second and the third day of the experiment LPS was injected additionally at 24 h intervals. Four and a half hours after the saline and pyrogen administration blood samples were collected from the control and experimental pigeons. The following immunological assays were performed: WBC, leucogram and immunophenotyping of lymphocyte subsets in peripheral blood, i.e. CD 3+ (T lymphocytes), CD 4+ (T helper lymphocytes) and CD 8+ (T suppressor/ cytotoxic lymphocytes) cells. In the conditions of endotoxin fever (i.e. after the first LPS injection) leucopenia, monocytopenia, heterophilia and eosinophilia were observed. Additionally, the immunophenotyping of peripheral blood lymphocytes indicated an increase in percentage of CD 3+, CD 4+ and CD 8+ cells in response to the single injection of LPS. In contrast, the consecutive injections of LPS, which created a pyrogenic tolerance effect, caused a decrease in WBC value, heteropenia, eosinopenia and lymphocytosis. Moreover, during this state an increase in percentage of CD 3+ and CD 8+ cells was demonstrated in contrast to the percentage of CD 4+ lymphocytes. The general tendencies in cellular immune response of the affected pigeons in the conditions of endotoxin fever and pyrogenic tolerance aim at activation of defence mechanisms against LPS for its prompt elimination from the animal’s organism.

5

The effect of multigenerational diet containing genetically modified triticale on immune system in mice

59%

Krzyzowska M., Wincenciak M., Winnicka A., Baranowski A., Jaszczak K., Zimny J., Niemaltowski M.

Polish Journal of Veterinary Sciences

|

2010

|

tom 13

|

nr 3

Ograniczanie wyników

Modulatory effect of the Euro-Lupus low-dose intravenous cyclophosphamide regimen on circulating immune cells in systemic lupus erythematosus

Acquired pericentric inversion of chromosome 9 in acute myeloid leukemia

The influence of different culture microenvironments on the generation of dendritic cells from non-small-cell lung cancer patients

Cellular immune response of pigeons in the conditions of endotoxin fever and pyrogenic tolerance

The effect of multigenerational diet containing genetically modified triticale on immune system in mice