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The melting of native domain structure in effector activation of IgG studied by using Congo Red as a specific probe

100%

Piekarska B., Roterman I., Rybarska J., Konieczny L., Kaszuba J.

Journal of Physiology and Pharmacology

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1994

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tom 45

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nr 1

2

IgG subclasses distribution in immunoglobulin preparations for intravenous use

88%

Bozadjiev L. G., Bineva I. L., Vassilev T. L.

Archivum Immunologiae et Therapiae Experimentalis

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1992

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tom 40

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nr 1

3

Intramolecular signalling in immunoglobulins - new evidence emerging from the use of supramolecular protein ligands

88%

Piekarska B., Konieczny L., Rybarska J., Stopa B., Spolnik P., Roterman I., Krol M.

Journal of Physiology and Pharmacology

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2004

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tom 55

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nr 3

The postulated intramolecular signaling in immunoglobulins generated by antigen binding has been controversial for years. The high heterogeneity of immune complexes as signaling systems and the requirement of the immobilized antigen form for efficient triggering of effector activity is likely the reason for the lack of clarity. Here we present new evidence supporting the notion of intramolecular signaling, based on the use of supramolecular dyes that bind to signal-derived specific sites in immunoglobulins.

4

When antibodies are antigens

88%

Milgrom F.

Archivum Immunologiae et Therapiae Experimentalis

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2003

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tom 51

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nr 2

5

HLA-A and -B type and haplotype frequencies in IgG subclass deficiency subgroups

75%

Barton J. C., Barton J. C., Bertoli L. F., Acton R. T.

Archivum Immunologiae et Therapiae Experimentalis

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2020

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tom 68

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nr 3

6

The influence of selected factors on the yield and quality of colostrum produced by Polish Holstein-Friesian cows

75%

Gulinski P., Gago V.

Acta Scientiarum Polonorum. Zootechnica

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2019

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tom 18

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nr 1

7

Surface analysis of IgM-expressing bovine lymphocytes in BLV-infected cattle by immuno-scanning electron microscopy

75%

Levkut M., Ponti W., Levkutova M., Turin L., Poli G.

Folia Histochemica et Cytobiologica

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1996

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tom 34

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nr 1

8

Ig[l-k]A1 - antigenic marker of light-chain immunoglobulins in pigs

75%

Wegrzyn J., Skiba E.

Roczniki Naukowe Zootechniki

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2000

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tom 27

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nr 2

9

The receptors regulating natural cytotoxic effector functions

75%

Nikolova M., Boumsell L., Bensussan A.

Archivum Immunologiae et Therapiae Experimentalis

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2001

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tom 49

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nr 2

10

Investigation on the relationship between lymphocyte subsets, immunoglobulin levels and adenosine deaminase activities in immunosuppressive dove methylprednisolone treated dogs

75%

Altug N., Agaoglu Z. T.

Bulletin of the Veterinary Institute in Puławy

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2007

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tom 51

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nr 1

Seven healthy dogs were administered with methylprednisolone orally (2 mg/kg body weight/d) at the beginning of the study (between 0-10 d), then the dosing was decreased at 10 d intervals throughout 10 to 60 d in an alternate-day therapy programme. Drug administration to the dogs was stopped on the 60 d. Total leukocyte count; polymorphonuclear leukocytes, and neutrophil ratios increased and eosinophil, mononuclear leukocytes, lymphocyte, and monocyte ratios were decrease when these values were compared to changes between days. Furthermore, in lymphocyte subsets, B lymphocytes and CD 8 T lymphocytes ratios were found to decrease. In addition, CD 3 T lymphocyte ratios decreased on the 61 d and CD 4 T lymphocyte ratios increased on the 21, 41, 51 and 61 d. IgM and IgG levels decreased between the days. Serum total ADA and ADA 1 activities decreased during the application, but ADA 2 activity did not change significantly. As a result, after immunosuppressive dose of methylprednisolone application, reduction in the ADA and ADA 1 activity can be used as determinant of the suppression of immune system components.

11

Modification of the ELISA for the determination of antibodies of IgG1, IgG2 and IgM classes in the serum of bovine leukaemia virus - infected animals

75%

Kozaczynska B.

Bulletin of the Veterinary Institute in Puławy

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1996

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tom 40

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nr 1

The aim of the experiments conducted was to modify the indirect ELISA to determine different immunoglobulin classes in the reaction of antibodies with bovine leukaemia virus. Rabbit sera immunized against bovine IgG₁, IgG₂ and IgM as well as serum conjugates were used in the modified method. Examinations of 100 reference serum samples from BLV-infected animals and 50 samples from BLV-free animals allowed us to establish the optimum dilution of the components used and the threshold optical densities of the test.

12

Carbohydrate moiety of immunoglobulins in health and pathology

75%

Krotkiewski H.

Acta Biochimica Polonica

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1999

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tom 46

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nr 2

Most of glycoproteins described so far, including immunoglobulins, are glycosylated during post-translational modifications of protein molecules. Current knowledge of the structure of sugar chains in immunoglobulin molecules and their biological role in health and pathology is reviewed.

13

Synthesis and immunological activity of mono- and disubstituted derivatives of 2,5-dimercapto-1,3,4-thiodiazoles

75%

Kowalczyk-Bronisz S. H., Pomorski J., Bubak B., Pregiel M., Blaszczyk B.

Archivum Immunologiae et Therapiae Experimentalis

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1995

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tom 43

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nr 3-4

14

Influence of a diet containing beta-carotene and omega-3 fatty acids on the biochemical and nonspecific humoral immunity indicators and on the results of experimental calf rearing

63%

Zwierzchowski G., Micinski J., Pogorzelska J., Siwicki A., Wojcik R., Kobzhassarov T. Z., Bermagambetova N., Shaikamal G. I., Fijalkowska M.

Journal of Elementology

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2016

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tom 21

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nr 1

The aim of this study has been to determine the effect of a diet containing β-carotene and omega-3 fatty acids on the biochemical and nonspecific humoral immunity indicators and on the results of rearing calves to day 60 of life. The study was conducted in 2011-2012, on a herd of Polish Holstein-Friesian cows. 54 calves from the herd were divided into 3 groups, 18 animals in each: CTR, TRT1 and TRT2. During the colostral period lasting for 5 days after birth, calves were drinking the mother’s colostrum. From 6 to 60 days, calves were watered milk replacer formulation. The control group (CTR) consisted of calves after the colostral period given milk replacer formulation without any supplementation. In the two other groups, calves received milk replacers with the supplementation of b-carotene (TRT1 group) in the amount of 25 mg/calf/day or a suspension of liver omega-3 oil (TRT2 group) in the amount of 5g/calf/day. All calves received solid feed ad libitum. The research showed that the parameters of the metabolic profile of calves (ALT, ASP, CHOL, GLU, UREA, ALP, TG, CRE) were within the normal range, indicating good health of the calves. Moreover, the supplementation had a positive impact on the chosen immunological parameters, including a higher IgG concentration, especially at the end of the milk drinking period. The result of B-carotene in a diet was the highest daily gain in the period from 30 to 60 days of life among the analysed groups of calves. No such effect was achieved in the TRT2 group of calves, as their body weight was the lowest. However, noteworthy is the beneficial impact of beta-carotene and omega-3 oil on the non-specific humoral immunity parameters, which was manifested by fewer cases of clinical diarrhoea and upper respiratory tract diseases.

15

Allergen-associated immunomodulators: modifying allergy outcome

63%

Gomez-Casado C., Diaz-Perales A.

Archivum Immunologiae et Therapiae Experimentalis

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2016

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tom 64

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nr 5

16

The impact of cow nutrition in the dry period on colostrum quality and immune status of calves

63%

Nowak W., Mikula R., Zachwieja A., Paczynska K., Pecka E., Drzazga K., Slosarz P.

Polish Journal of Veterinary Sciences

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2012

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tom 15

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nr 1

The objective of the study was to evaluate the effect of energy contents in a dry period diets in “7+1” feeding strategy of dry cow including 7 weeks of the dry period (far-off) and 1 week of a close-up period, on colostrum quality and the immune status of calves. Forty Holstein multiparous cows were dried at 56d before the expected date of calving and were assigned to the higher energy diet group (HE; 0.69 UFL/kg DM, NDF 52% DM), or the lower energy diet group (LE; 0.61 UFL/1kg DM, NDF 56% DM). From -7d to the expected calving date up to 21 d of lactation, all cows were fed the same fresh, lactation diet. Samples of colostrum were collected within 2h after parturition and its density, dry matter content and concentrations of immunoglobulins, fat, protein, lactose, urea and somatic cell counts were measured. Calves were weighed 2 h after calving and on the 21d of life. On 3d and 21d of calves’ life blood samples were collected and the concentration of IgG, IgA, IgM, insulin-like growth factor 1 (IGF-1) as well as total protein and albumin concentrations were determined. Treatments had no significant effect on composition of colostrum and serum immunoglobulins and IGF-1 concentration. In both groups the weight of calves at birth was similar, still daily body weight gain during 21 day of rearing period in HE group was higher than in the LE group (P=0.05).

17

Hymenolepis diminuta antigen: detection in faeces of rats

63%

Machnicka B., Krawczuk S.

Bulletin of the Polish Academy of Sciences. Biological Sciences

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1988

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tom 36

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nr 4-6

18

CD40-activated B cells from patients with systemic lupus erythematosus can be modulated by therapeutic immunoglobulins in vitro

63%

Neron S., Boire G., Dussault N., Racine C., De Brum-Fernandes A. J., Cote S., Jacques A.

Archivum Immunologiae et Therapiae Experimentalis

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2009

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tom 57

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nr 6

447-458

19

Pathological findings in cornea tissue of patients with penetrating keratoplasty

63%

Kostelna H., Rosocha J., Paulikova E., Kozak I., Antalova M., Mahel M., Harvanova D., Petrovicova J., Bobak L.

Folia Histochemica et Cytobiologica

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2010

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tom 48

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nr 2

267-272

20

The presence of anti-Yersinia pseudotuberculosis immunoglobulins in equine serum

63%

Czernomysy-Furowicz D., Silecka A., Nawrotek P., Jankowiak D., Karakulska J., Furowicz A.

Polish Journal of Veterinary Sciences

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2010

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tom 13

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nr 4

The research was conducted on clinically healthy mares (n=40) and foals (n=78) duringY. pseudotuberculosis associated enzootics. The animals were divided into groups: I to IV – mares, IA to IVA – their offsprings, IB to IVB – foals which mothers were not treated with any medicaments. The animals in group I, IA and IB were injected with PBS; in group II, IIA and IIB – with Y. pseudotuberculosis strain-based vaccine, in group III, IIIA and IIIB – with P. acnes strain-based immunostimulator; in group IV, IVA and IVB – with P. acnes strain-based immunostimulator and (5 days after the immunostimulator injection)Y. pseudotuberculosis strain-based vaccine. The presence of antibodies was determined by means of ELISA. The study revealed anti-Yersinia pseudotuberculosis IgG only in 19 mares before, and in 25 mares and 26 foals 3 weeks after vaccination. The mean extinction 3 weeks after vaccination amounted to: II-0.489, IV-2.578, IIA-0.572, IVA-0.974, IIB-0.312, IVB-0.418. The cut-off extinction value was 0.154. The presence of anti-Yersinia pseudotuberculosis IgG before vaccination in the sera of clinically healthy mares may suggest that Y. pseudotuberculosis infection occurs definitely more often than is expected. Vaccination preceded by immunostimulation appeared to be the most efficient method of treatment against yersiniosis.

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