Wyniki wyszukiwania

1

Infant nutrition and the child health services

100%

Ginsburg B. E.

Żywienie Człowieka i Metabolizm

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1988

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tom 15

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nr 4

Omówiono problemy zdrowotne spowodowane wadliwym żywieniem niemowląt i dzieci przedszkolnych a także zmiany w rozpowszechnieniu karmienia piersią w Szwecji. Opisano główne nieprawidłowości w żywieniu dzieci przedszkolnych oraz cele oświaty zdrowotnej dla rodziców. Zwrócono uwagę na powiązania między karmieniem sztucznym, dostarczającym dużych ilości białka a hiperinsulinemią u niemowląt do 6 miesiąca życia.

2

Age-related changes of Na plus, K plus - ATPase, Ca plus2 - ATPase and Mg plus2 - ATPase activities in rat brain synaptosomes

100%

Torlinska T., Grochowalska A.

Journal of Physiology and Pharmacology

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2004

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tom 55

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nr 2

Cerebral metabolism of glucose, one of the determinants of tissue ATP level, is crucial for central nervous system function. The activity of P-type pumps, namely Na+, K+ - ATPase, Ca+2 - ATPase and Mg+2 - ATPase were examined in brain synaptosomes of 5 - day, 3 - month and 18 - month - old rats to determine if changes in enzyme activity related to aging are potentially associated with alterations in glucose homeostasis. Activities of all the ATPases studied in isolated brain synaptosomes were expressed in µmol of Pi liberated from ATP by 1 mg of synaptosome protein during one hour. Serum glucose concentration was measured by the glucose oxidase method and insulin level was estimated by the RIA. Our results demonstrate that 18 - month - old rats are characterized by hyperglycemia and hyperinsulinemia. Their serum glucose concentration was significantly increased approx. 62.3% and 135.8 % as compared to 3 - month - old rats and 5 - day, newborn rats, respectively. An enormous increase in serum insulin concentration in the old, hyperglycemic rats was observed concomitantly. As a result of these changes the insulin - to - glucose ratio in the old rats was greatly increased approx. (270% and 230%) compared to young, mature and newborn rats. Hyperglycemia and hyperinsulinemia occurring in the old rats, had a different impact on activities of the ATPases tested. Our results have revealed that Na+, K+ - ATPase activity remains almost unchanged with age, the activity of Ca+2 - ATPase decreases, whereas that of Mg+2 - ATPase increases significantly in old, insulin resistant rats. In conclusion it seems that changes in activity of different P - type pumps may differ with aging and that adaptation of specific ATPases to internal environment alterations is not identical.

3

The influence of orlistat, metformin and diet on serum levels of insulin-like growth factor-1 in obese women with and without insulin resistance

80%

Kujawska-Luczak M., Szulinska M., Skrypnik D., Musialik K., Swora-Cwynar E., Kregielska-Narozna M., Markuszewski L., Grzymislawski M., Bogdanski P.

Journal of Physiology and Pharmacology

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2018

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tom 69

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nr 5

4

The impairment of IGF-I-stimulated protein synthesis and activation of protein kinase B, p70S6k, MAP kinase, and p90rsk in mouse C2C12 myogenic cells exposed to high glucose and high insulin

80%

Grzelkowska-Kowalczyk K., Wieteska W.

Polish Journal of Veterinary Sciences

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2005

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tom 08

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nr 3

5

Basal and postprandial plasma levels of PYY, ghrelin, cholecystokinin, gastrin and insulin in women with moderate and morbid obesity and metabolic syndrome

80%

Zwirska-Korczala K., Konturek S. J., Sodowski M., Wylezol M., Kuka D., Sowa P., Adamczyk-Sowa M., Kukla M., Berdowska A., Rehfeld J. F., Bielanski W., Brzozowski T.

Journal of Physiology and Pharmacology. Supplement

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2007

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tom 58

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nr 1

13-35

6

The relationship between vitamin D3 and insulin in polycystic ovary syndrome - a critical review

80%

Kaminska K., Grzesiak M.

Journal of Physiology and Pharmacology

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2021

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tom 72

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nr 1

7

In vivo and in vitro effects of hyperglycemia on Naplus-Kplus, Caplus2, Mgplus2-dependent ATPases activity in brain synaptosomes of aging rats

80%

Torlinska T., Grochowalska A., Kupisz J., Skoracka J., Kojo S.

Journal of Physiology and Pharmacology. Supplement

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2006

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tom 57

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nr 7

145-158

Cerebral metabolism of glucose, one of the determinants of tissue ATP level, is crucial for the CNS function. The activity of P-type pumps: Na+, K+-ATPase, Ca+2-ATPase and Mg+2-ATPase were examined in rat brain synaptosomes to determine if changes in the enzyme activity related to aging are potentially associated with alterations in glucose homeostasis. Male Wistar rats (newborn, 3- and 18-month-old) were sacrificed by decapitation and synaptic plasma membranes were isolated from brains. In vivo study demonstrated that 18-month-old rats were characterized by hyperglycemia, hyperinsulinemia and increased total antyoxidative status (TAS) level. These conditions had a different impact on activities of the ATPases tested in vivo: only the activity of Ca+2-ATPase decreased whereas that of Mg+2-ATPase increased significantly. In vitro experiments, prior incubation of isolated synaptosomes with glucose of concentrations corresponding to normoglycemia in vivo (4.5 - 6.5 mM), stimulated Ca+2-ATPase activity, whereas higher glucose concentrations (10.0 - 12.5 mM) inhibited significantly the enzyme activity. The most sensitive to hyperglycemia appeared Na+, K+-ATPase in old rats synaptosomes with the progressive decline starting at 6.5 mM glucose. The activity of Mg+2-ATPase was not inhibited in vitro even at high glucose concentrations that may explain the increased in vivo, activity of this enzyme in old, hyperglycemic rats.

8

Morphological and histochemical studies of the endocrine pancreas in persistent hyperinsulinemic hypoglycemia

80%

Kunz J.

Folia Histochemica et Cytobiologica

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1984

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tom 22

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nr 3-4

9

Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik

Effect of Mimosa pudica cured extract against high fructose diet induced type 2 diabetes in rats

80%

Sundaresan A., Radhiga T.

International Letters of Natural Sciences

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2015

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tom 39

The study evaluated the effects of Mimusa pudica (M. pudica) leaf extract on type 2 diabetes in rats fed high fructose diet (HFD). Rats were fed either control diet or HFD for 14 days, following which the diet was fortified with M. Pudica at a dose of 500 mg/kg BW. After 8 weeks, HFD caused deleterious metabolic effects, including increased body weight, hyperglycemia, hyperinsulinemia, dyslipidemia and liver dysfunction. Further, rats fed HFD alone showed increased activities of hepatocellular enzymes in plasma and lipid deposition in liver. Treatment with M. pudica significantly reduced the body weight, improved insulin sensitivity, managed the dyslipidemia and reduced liver damage towards normal. Histopathology of the liver confirmed the changes induced by HFD and the M. pudiac treatment significantly reversed towards normality. These data suggest that M. pudica treatment improve insulin sensitivity and attenuates fat accumulation in liver.

10

Result of oral intake of glucose by healthy subjects and patients with essential hypertension on the binding and degradation of 125I-insulin by erythrocyte receptors

80%

Szczesniak L., Rychlewski T., Gluszek J., Michocki P., Banaszak F.

Journal of Physiology and Pharmacology

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1996

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tom 47

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nr 2

11

Age dependent changes of insulin receptors in rat tissues

80%

Torlinska T., Mackowiak P., Nogowski L., Hryniewiecki T., Witmanowski H., Perz M., Madry E., Nowak K. M.

Journal of Physiology and Pharmacology

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2000

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tom 51

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nr 4,2

12

The metabolic syndrome – an ongoing story

71%

Duvnjak L., Duvnjak M.

Journal of Physiology and Pharmacology. Supplement

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2009

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tom 60

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nr 7

Ograniczanie wyników

Infant nutrition and the child health services

Age-related changes of Na plus, K plus - ATPase, Ca plus2 - ATPase and Mg plus2 - ATPase activities in rat brain synaptosomes

The influence of orlistat, metformin and diet on serum levels of insulin-like growth factor-1 in obese women with and without insulin resistance

The impairment of IGF-I-stimulated protein synthesis and activation of protein kinase B, p70S6k, MAP kinase, and p90rsk in mouse C2C12 myogenic cells exposed to high glucose and high insulin

Basal and postprandial plasma levels of PYY, ghrelin, cholecystokinin, gastrin and insulin in women with moderate and morbid obesity and metabolic syndrome

The relationship between vitamin D3 and insulin in polycystic ovary syndrome - a critical review

In vivo and in vitro effects of hyperglycemia on Naplus-Kplus, Caplus2, Mgplus2-dependent ATPases activity in brain synaptosomes of aging rats

Morphological and histochemical studies of the endocrine pancreas in persistent hyperinsulinemic hypoglycemia

Effect of Mimosa pudica cured extract against high fructose diet induced type 2 diabetes in rats

Result of oral intake of glucose by healthy subjects and patients with essential hypertension on the binding and degradation of 125I-insulin by erythrocyte receptors

Age dependent changes of insulin receptors in rat tissues

The metabolic syndrome – an ongoing story