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Effects of the presence of sporocysts, rediae and cercariae of Fasciola hepatica on the lipid content in the digestive gland of Lymnaea truncatula as well as on lipid levels in tissues of the parasites themselves were studied. Lipids were examined by means of histochemical and cytophotometric techniques. The snail's digestive gland lipid level was found to be almost halved in 20 days post infection; a more then 80% reduction being visible after the subsequent 40 and 60 days. The loss of lipids in the digestive gland of the infected snails point at mobilisation of lipid energy reserves to compensate for the deficiency of carbohydrates, used by these parasites. The parasite tissues such as tegument, pharynx, suckers and germ balls showed considerable lipid contents and were metabolically active. It supports the hypothesis that lipids are used as energy source by developmental stages of this parasite.
Results of micromorphological and histological studies of larvae of Trichinella Spiralis and T. pseudospiralis, as weil as, muscles, liver and small intestine of the rat-host before and after biostimulator administration of phytohemagglutinin and phytoanthelminthic were presented. It has been established that rats with Trichinella larvae of both species developed unspecific allergic angiomyositis, hepatitis, cholangitis, and erosio-haemorrhagic enterocolitis in the host's organism on the 35th day after infection. Furthermore, processes of compensatory hypertrophy, that support the host's (rats) homeostasis, on cell and tissue levels, were observed at histodestructional and morphofunctional deficiency. lt has been revealed that phytohemagglutinin, biostimulator injected into the host's organism before infection, is of immunostimulating nature and partially destroys the larvae of Trichinella. The phytoanthelminthic produces a significant trichinellocide effect: RNA synthesis and glycogen is intensified in the organs of the treated animals, their pathomicromorphogenesis weakened, and their compensatory and regenerative processes were observed. The combined use of the phytohemagglutinin and phytoanthelminthic fails to intensify the mentioned effect.
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