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1
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Sleep disordered breathing in the elderly: comparison of women and men

100%
Hader C., Schroeder A., Hinz M., Micklefield G. H., Rasche K.
Journal of Physiology and Pharmacology. Supplement
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2005
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tom 56
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nr 4
85-91
The prevalence of obstructive sleep apnea syndrome in patients up to the age of 60 is known to be two times higher in men then in women. Hormonal changes during menopause might underlie changes in this relationship in the elderly. This study was designed to detect differences in the type and frequency of sleep-disordered breathing between women and men over the age of 65 years, having the same body mass index. The study was conducted using a matched-pair approach consisting of a sample population of 40 pairs of patients over the age of 65. All patients met the following exclusion criteria: age below 65, heart failure, chronic obstructive lung disease. Polygraphy was conducted by means of a portable recorder. All measured indices were higher in men than in women. The apnea index was 2.8 ±4.1 in men and 0.6 ±1.4 in women. The apnea/hypopnea index was 10.2 ±11.4 and 4.8 ±3.9, respectively. These differences were significant (P<0.05). Significant differences also were observed when central (men 8.1 ±13.1, women 3.1 ±8.2), mixed (men 5.1 ±11.4, women 0.4 ±1.3), and obstructive (women men 8.6 ±20.1, 1.0 ±4.3) apnea indices were compared. In conclusion, the study demonstrates that elderly patients showed gender-dependent differences in the type and frequency of sleep-related breathing disorders. Men suffered from all kinds of apnea more frequently than women.
2

Metformin decreases the expression of VEGF-A and CTGF-1 and improves histological, ultrastructural and hormonal changes in adult rat polycystic ovary

100%
Attia G. M., Elmansy R. A., Elsayed M. H.
Folia Biologica
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2019
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tom 67
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nr 1
3
Content available remote

Plasma adrenomedullin response to maximal exercise in healthy subjects

100%
Krzeminski K., Mikulski T., Kruk B., Nazar K.
Journal of Physiology and Pharmacology
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2003
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tom 54
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nr 2
The aim of the study was to find out whether maximal exercise performed by healthy young men influences plasma adrenomedullin concentration (ADM) and is the peptide level related to the cardiovascular, metabolic and hormonal changes induced by exercise. Ten subjects (age 24 ± 1.0 yr) participated in the study. They performed graded bicycle ergometer exercise until exhaustion. Heart rate (HR) and blood pressure (BP) were measured throughout the test. Before and at the end of exercise venous blood samples were taken for [ADM], noradrenaline [NA], adrenaline [A], growth hormone [hGH], cortisol and lactate [LA] determination. Plasma [ADM] decreased during exercise from 1.71 ± 0.09 to 1.53 ± 0.10 pmol × l-1 (p< 0.01). This was accompanied by increases in plasma catecholamines and [hGH], while plasma cortisol level did not change. Positive correlation was found between the exercise-induced decreases in plasma ADM and diastolic BP. Blood [LA], systolic and mean BP at the end of exercise correlated negatively with plasma [ADM]. No significant interrelationships were found between plasma ADM, catecholamines or the other hormones measured. The present data suggests, that maximal exercise inhibits ADM secretion in young healthy men. Metabolic acidosis and a decrease in peripheral resistance might be involved in this effect.
4
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The effect of endurance training on muscle strength in young, healthy men in relation to hormonal status

80%
Grandys M., Majerczak J., Duda K., Zapart-Bukowska J., Sztefko K., Zoladz J. A.
Journal of Physiology and Pharmacology. Supplement
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2008
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tom 59
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nr 7
5
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Serum melatonin, corticosterone and thyroid hormones in irradiated rats: effect of exposure during various times of day of light regimen

80%
Ahlersova E., Kassayova M., Ahlers I.
Journal of Physiology and Pharmacology
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1997
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tom 48
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nr 3
6
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Hormonal changes in dairy cows during periparturient period

71%
Kurpinska A., Skrzypczak W.
Acta Scientiarum Polonorum. Zootechnica
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2019
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tom 18
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nr 4
7

The function of pituitary-thyroid axis in male patients with posthepatitic and alkoholic cirrhosis

61%
Marek B., Buntner B., Ostrowska Z., Sawaryn T., Beniowski M., Kos-Kudla B., Zwirska-Korczala K., Swietochowska E., Kajdaniuk D.
Bulletin of the Polish Academy of Sciences. Biological Sciences
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1995
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tom 43
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nr 1
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