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Infections caused by RSV among children and adults during two epidemic seasons

100%

Pancer K., Ciacka A., Gut W., Lipka B., Mierzejewska J., Milewska-Bobula B., Smorczewska-Kiljan A., Jahnz-Rozyk K., Dzierzanowska D., Madalinski K., Litwinska B.

Polish Journal of Microbiology

2011

tom 60

nr 3

Respiratory Syncytial Virus (RSV) is one of the most common causes of lower respiratory tract infections in young children, immunocompromised patients (children and adults), patients with chronic respiratory diseases and elderly people. Reinfections occur throughout the life, but the severity of disease decreased with subsequent infection. The aim of this study was to analyze the frequency of RSV infections in two selected subpopulations: young children (below 5 y.) and adults with chronic respiratory diseases (25–87 y.). Nasopharyngeal swabs (334) collected from October 2008 to March 2010 were examined. The presence of RSV genome was determined by RT-PCR and the presence of RSV antigen by quick immunochromatographic test. Positive results of RT-PCR were found in 45.2% of all swabs: 48.6% samples in 2008; 41.5% in 2009; 50.8% in 2010. The highest frequency of RSV-positive samples was in fall-winter months, but differences in RSV epidemic seasons were found. In the first season (2008–2009) an increased number of RSV infections was observed from November 2008, but in the second season – from January 2010. Generally, the frequency of RSV-positive RT-PCR among children was 53%, among adults 25%. The highest difference was observed in the first three-month period of 2010. RT-PCR positive samples were found in 68.5% of children and 5.9% of adults. However, the RSV antigen was found in 44.4% of samples collected from adults in this period. Our results indicate that the contribution of RSV infections during epidemic season of respiratory tract infections in Poland was really high among children and adults.

Development of a new, simple and cost-effective diagnostic tool for genetic screening of hereditary colorectal cancer - the DNA microarray assay

100%

Stojcev Z., Banasiewicz T., Kaszuba M., Sikorski A., Szczepkowski M., Bobkiewicz A., Paszkowski J., Krokowicz L., Biczysko M., Szmeja J., Jurkowska M., Majewski P., Mackiewicz A., Lamperska K., Drews M., Wojciechowicz J.

Acta Biochimica Polonica

2013

tom 60

nr 2

Detection of mutations in families with a hereditary predisposition to colon cancer gives an opportunity to precisely define the high-risk group. 36 patients operated on for colon cancer, with familiar prevalence of this malignancy, were investigated using the DNA microarrays method with the potential detection of 170 mutations in MLH1, MSH2, MSH6, CHEK2, and NOD2 genes. In microarrays analysis of DNA in 9 patients (25% of the investigated group), 6 different mutations were found. The effectiveness of genetic screening using the microarray method is comparable to the effectiveness of other, much more expensive and time-consuming methods.

Antibody response to influenza vaccination in patients suffering from asthma

80%

Romanowska M., Rybicka K., Nowak I., Jozefczuk J., Zycinska K., Radzikowska A., Brydak L. B.

Journal of Physiology and Pharmacology. Supplement

2007

tom 58

nr 5

Serum tumor necrosis factor-alpha and interleukin-10 levels as markers to predict outcome of patients with chronic lymphocytic leukemia in different risk groups defined by the IGHV mutation status

80%

Lech-Maranda E., Grzybowska-Izydorczyk O., Wyka K., Mlynarski W., Borowiec M., Antosik K., Cebula-Obrzut B., Makuch-Lasica H., Nowak G., Klimkiewicz-Wojciechowska G., Wawrzyniak E., Bilinski P., Robak T., Warzocha K.

Archivum Immunologiae et Therapiae Experimentalis

2012

tom 60

nr 6

Screening for germline p53 mutations in pediatric and adult patients of high-risk groups in Poland

80%

Fiszer-Maliszewska L., Czernik J., Sawicz-Birkowska K., Perek D., Kozera M., Wojciechowska B., Kazanowska B., Hudziec P., Kilar E.

Archivum Immunologiae et Therapiae Experimentalis

2000

tom 48

nr 4

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Wyniki wyszukiwania

Infections caused by RSV among children and adults during two epidemic seasons

Development of a new, simple and cost-effective diagnostic tool for genetic screening of hereditary colorectal cancer - the DNA microarray assay

Antibody response to influenza vaccination in patients suffering from asthma

Serum tumor necrosis factor-alpha and interleukin-10 levels as markers to predict outcome of patients with chronic lymphocytic leukemia in different risk groups defined by the IGHV mutation status

Screening for germline p53 mutations in pediatric and adult patients of high-risk groups in Poland