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The study was performed on 110 great saphenous veins in human foetuses of both sexes aged 9 to 37 weeks. The earliest well-shaped valves were observed in foetuses aged 13 weeks. In these foetuses the number of valves varies from 2 to 7. Consecutive microscopic sections revealed that the developing valves at their origin present thickening of the endothelium which is continuous into the cusps of the valves. The bicuspid cusps are crescent-shaped and both surfaces are lined by endothelium.
Background. Acute ascending thrombophlebitis of the great saphenous vein (GSV) is an adverse complication of varicose veins of the lower extremities. Conventional surgical treatment comprises traumatic removal of thrombotic vein trunk by means of a Babcock probe. Endovascular welding is a promising, minimally invasive treatment for varicose veins, which may also be applied for hemodynamic correction of impaired venous blood flow of the lower extremities in urgent conditions. Material and methods. Thirty-six patients diagnosed with acute ascending thrombophlebitis type III and IV, stage C2-C6 (CEAP) were treated using an EK300M electric welding device (LLC Svarmed, Ukraine) for high-frequency electric welding of living tissues guided by endovenous probes. Changes in the treated venous trunks were analyzed by ultrasound, and quality of life before and after surgical treatment was evaluated using a chronic insufficiency venous international questionnaire (CIVIQ). Results. Twelve months after high-frequency endovenous electric welding 33 patients (91.41%) had complete occlusion and fibrous transformation in areas of the thrombus segments of the GSV. Two patients (5.54%) had hemodynamically insignificant partial recanalization of separate vein segments, and one patient (2.77%) had complete recanalization of the GSV trunk. Conclusions. Endoscopic welding is an effective, minimally traumatic alternative method for the surgical treatment of acute ascending thrombophlebitis III and VI type of the GSV.
There are 3 groups of perforating veins of the shin: the medial, the lateral and the internal sural perforating veins. Dysfunction of these veins is one of the main factors in venous hypertension. There is a lack of data in the literature concerning perforating veins of the shin in human foetuses. The aim of this study was identification of the perforating veins of the shin in human prenatal development. The material examined included 88 human lower limbs of foetuses (21 males and 23 females) aged from 16 to 38 weeks of intra-uterine life. The perforating veins were dissected under a steromicroscope. The number of perforating veins was analysed in relation to the sex of the foetus and the side of a body. In our study perforating veins of the shin did not show sexual or syntopic dimorphism. Between 2 and 6 Cockett’s perforating veins were constantly present. Of these veins 80% divided into ascending and descending branches. Fibular perforating veins were found more often (90.9%) than Boyd’s perforating veins (21.6%). Between 1 and 3 fibular perforating veins were observed but in 9% of cases they were entirely absent.
The aim of the study was to show the changes in the great saphenous vein (GSV) wall at consecutive stages in the development of chronic vein disease (CVD) in patients qualified for a surgical procedure after physical examination and Doppler ultrasonography. Four groups of patients were formed (C2, C3, C4 and C5/6) according to clinical stage of the CEAP classification (C — clinical signs, E — aetiopathology, A — anatomy and P —pathophysiology). After the surgical procedure for removal of the varicose GSVs, 40 segments were harvested from their proximal parts near the saphenofemoral junction, 10 segments for each CEAP group. The veins were sectioned transversally and stained with the resorcin-fuchsin and AZAN method to visualise the elastic end collagen fibres. Afterwards the specimens were analysed under an optical microscope and photographed. As the GSV is an elastic vessel and its wall is divided into three zones, namely the internal layer (intima), the medial layer (media) and the external layer (adventitia), we found a proliferation of the connective tissue among the smooth muscle cells inside the internal and medial layers at consecutive stages of CVD. The later stages of CVD also revealed a larger number of the elastic and collagen fibres inside the intima and media and a looser arrangement of the smooth muscle cells of the media in the GSV wall.
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