Wyniki wyszukiwania

1

Does prolactin influence the hypothalamo-pituitary GnRH-LH system in preovulatory-phase ewes?

100%

Misztal T., Romanowicz K., Wankowska M., Wojcik-Gladysz A., Polkowska J.

Reproductive Biology

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2005

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tom 05

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nr 1

2

The role of GABAA and GABAB receptors in the control of GnRH release in anestrous ewes

100%

Tomaszewska-Zaremba D., Przekop F.

Reproductive Biology

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2006

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tom 06

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nr Suppl.2

3

Detection of gonadotropin-releasing hormone and somatostatin-14 containing cells in the mammary gland of guinea pigs

100%

Gencer T. B., Yaman M., Bayrakdar A.

Medycyna Weterynaryjna

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2007

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tom 63

|

nr 10

1193-1195

The existence of numerous neuropeptides in milk is well established. It is still unclear whether these neuropeptides are produced by the mammary gland or that the gland concentrates them from the general circulation. The aim of the study was to examine the possible localization of these neuropeptides in the mammary gland of guinea pigs at different physiological states by immunohistochemistry. Specific primers have been used for the somatostatin, vasoactive intestinal polypeptide, neurotensin, cholecystocinin, oxytocin, gonadotropin-releasing hormone and growth hormone. Among all the neuropeptides that have been examined gonadotropin-releasing hormone and somatostatin immunoreactivity were found in the mammary gland of lactating guinea pigs, but not in virgin and pregnant guinea pigs. Immunoreactivity was observed in the epithelial cells that compose the secretory alveoli and in the secretory material

4

Serum progesterone concentrations on the day of oocyte retrieval above 9.23 ng/ml may predict ovarian hyperstimulation syndrome risk in in vitro fertilized patients

100%

Issat T., Nowicka M. A., Oleksik T. P., Zagozda M., Koziol K., Jakimiuk A. A., Lewandowski P., Jakimiuk A. J.

Journal of Physiology and Pharmacology

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2019

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tom 70

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nr 5

5

Molecular targets for immunocontraception

100%

Stoyka B., Domagala A., Kurpisz M.

Archivum Immunologiae et Therapiae Experimentalis

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2003

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tom 51

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nr 1

6

Modulation of anterior pituitary cell luteinizing hormone secretory activity by neuropeptide Y in early pregnant pigs

84%

Siawrys G., Buchowski H.

Journal of Physiology and Pharmacology

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2018

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tom 69

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nr 5

7

Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik

Effects of corticotropin releasing hormone and corticotropin releasing hormone antagonist on biosynthesis of gonadotropin releasing hormone and gonadotropin releasing hormone receptor in the hypothalamic-pituitary unit of follicular-phase ewes and contribution of kisspeptin

84%

Ciechanowska M., Kowalczyk M., Lapot M., Malewski T., Antkowiak B., Brytan M., Winnicka I., Przekop F.

Journal of Physiology and Pharmacology

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2018

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tom 69

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nr 3

8

Artificial spawning of pikeperch (Sander lucioperca (L.)) stimulated with human chorionic gonadotropin (hCG) and mammalian GnRH analogue with a dopamine inhibitor

84%

Zakes Z., Demska-Zakes K.

Archives of Polish Fisheries

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2005

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tom 13

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nr 1

The aim of the experiment was to identify the possibilities of stimulating pikeperch spawning with human chorionic gonadotropin (hCG) and Ovopel, a mammalian GnRH analogue (D-Ala⁶ Pro⁹ NEt-mGnRH) with a dopamine inhibitor (metoclopramide). Pikeperch spawners were caught with trap gear (fyke-nets) during the pre-spawning season from the Tałty and Tałtowisko lakes (Masurian Lakeland, northern Poland). After transport that lasted an hour, the fish were placed in tanks in a recirculating system and then segregated by sex. The females were divided into five experimental groups, each containing six specimens. The fish were injected twice at 24 hour intervals with hCG (group I - 200 and 200IU kg⁻¹ body weight (BW); group II - 200 and 500IU kg⁻¹ BW), Ovopel (group III - 0.25 and 0.50 pellets kg⁻¹ BW; group IV - 0.25 and 1.0 pellets kg⁻¹ BW) or 0.7% NaCl solution (group V, control - 0.2 and 0.5 cm³ kg⁻¹ BW). The effects of the hormonal stimulation expressed as the percentage of ovulating females, the degree of spawning synchronicity, and survival of the embryos to the eyed-egg stage were highly differentiated. The highest percentages of spent fish were obtained in the group stimulated with hCG - 83.3% (group I) and 100% (group II) of the females ovulated. The development of the oocytes in this group was rapid and synchronous, which was reflected in the shortened and relatively similar latency period (47 - 57 hours following the first injection; mean ≈ 51 hours) in individual females. No impact was noted with regard to hCG dose (400 vs. 700 IU kg⁻¹ BW) on the latency time or on egg quality. Ovopel did not positively affect either oocyte maturation or pikeperch ovulation. None of the fish from group III ovulated, and in group IV, as in the control group, eggs were obtained only from three (50%) females. In contrast to group V, the eggs of females stimulated with Ovopel were of low biological quality and survival to the eyed-egg stage ranged from 0 to 8%. Higher mortality among the females was also noted, especially in group III. The experiment indicated that hormonal stimulation with hCG is effective, while that with Ovopel was surprisingly ineffective.

9

Vasopressin release from the rat hypothalamo-neurohypophysial system: effects of gonadotrophin-releasing hormone [GnRH], its analogues and melatonin

84%

Boczek-Leszczyk E., Stempniak B., Juszczak M.

Journal of Physiology and Pharmacology

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2010

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tom 61

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nr 4

459-466

The influence of gonadotrophin-releasing hormone (GnRH) and its analogues (i.e., agonist and antagonist) on vasopressin (VP) release from the rat hypothalamo-neurohypophysial (H-N) system was studied both in vitro and in vivo. Additionally, it was determined whether the possible response of vasopressinergic neurones to these peptides could be modified by melatonin through a cAMP-dependent mechanism. In this study we demonstrate, for the first time, that the highly selective GnRH agonist (i.e., [Des-Gly10,D-His(Bzl)6,Pro-NHEt9]-LHRH; histrelin) stimulates the release of VP from the rat H-N system, while native GnRH and its antagonist remain inactive in modifying this process in vitro. Melatonin significantly inhibited basal and histrelin-induced release of VP in vitro, but displayed no significant influence on VP secretion when GnRH or its antagonist were present in a medium. Melatonin fully suppressed forskolin-stimulated VP release from the rat H-N system. On the other hand, addition of forskolin to a medium containing both histrelin and melatonin did not further alter the inhibitory influence of melatonin on the histrelin-dependent release of VP in vitro. After intracerebroventricular (i.c.v.) infusion of native GnRH or its agonist, blood plasma VP concentration was significantly higher than in control animals, which was accompanied by decreased content of the hormone in the neurohypophysis. Intravenous (i.v.) injection of melatonin did not change, in any subgroup, blood plasma VP concentration, when compared to the vehicle-injected rats. However, the neurohypophysial levels of the hormone were significantly higher after melatonin injection in control, GnRH- and histrelin-infused animals. Our present results suggest that activation of the GnRH receptor in the hypothalamus is involved in stimulation of VP secretion from the rat H-N system. We have also shown that melatonin, at a concentration close to its physiological level in the blood, significantly reduces the in vitro response of vasopressinergic neurones to a GnRH agonist - histrelin; this effect of melatonin could be mediated through intracellular processes that involve, among others, the cAMP-dependent mechanism.

10

Gonadotropin-releasing hormone and kisspeptin-10 regulate nuclear receptor subfamily 5 group a member 1/catenin beta 1/nuclear receptor subfamily 0 group B member 1 activity in female rat anterior pituitary gland

84%

Zielinska-Gorska M., Gorski K., Biernacka K., Sawosz E., Kaminski T., Gajewska A.

Journal of Physiology and Pharmacology

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2018

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tom 69

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nr 3

11

The gonadotropins subunits, GNRH and GnRH receptor gene expression and role of carbon monoxide in seasonal breeding animals

84%

Romerowicz-Misielak M., Koziorowski M.

Annals of Animal Science

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2012

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tom 12

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nr 1

12

Castration in male pigs: techniques and animal welfare issues

84%

Thun R., Gajewski Z., Janett F.

Journal of Physiology and Pharmacology. Supplement

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2006

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tom 57

|

nr 8

189-194

Castration in male pigs is usually performed during the first weeks of life without prior anesthesia. This technique, however, is known to induce acute pain and stress and will therefore not be tolerated any longer by animal welfare organizations. Practical and animal-friendly alternatives to surgical castration are the production of entire male pigs, semen sexing or immunological castration. Fattening boars has the benefits of better feed efficiency, higher lean meat yield and increased animal welfare due to no pain and stress of castration. The most important disadvantage in raising entire male pigs is the incidence of boar taint ranging between 10 and 75%. To identify tainted carcasses an accurate and rapid on-line method for detection of odorous compounds is absolutely necessary. Sperm sexing through flow cytometry is the only commercially available method at the moment but speed of separation is too low for practical application. Active immunization of boars against gonadotropin-releasing-hormone (GnRH) at the end of the fattening period results in a significant reduction of testicular weight and androstenone production while the benefits of daily growth gain, meat quality as well as welfare remain the same as in entire males. In the present review more detailed information is given about the various techniques, especially the practical application of immunocastration on a large scale base.

13

Evolution of gonadotropin-releasing hormone (GnRH) structure and its receptor

84%

Kochman K.

Journal of Animal and Feed Sciences

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2012

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tom 21

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nr 1

It is evident now that the gonadotropin-releasing hormone (GnRH) structure was already in existence very early in the evolution of animals and was co-opted in diverse ways to regulate reproduction. During 600 million years of animal evolution, the N and C termini of GnRH have been conserved as functional domains for binding and activating cognate receptors to accomplish its functions. About 400 millions years ago, a single substitution of the chiral amino acid in position 6 of GnRH in jawless fish by the achiral glycine facilitated a type II’ β-turn conformation of GnRH to allow spatially close interaction of functional domains of GnRH with receptors, in contrast to the interaction of more extended GnRH structures with their cognate receptors in earlier-evolved species. GnRH II was preconfigured to this conformation through intramolecular interactions, which accounts for its high binding affinity and total conservation of primary structure over 400 million years of evolution. It is very surprising and fascinating that the coordinated evolutionary selection of amino acids participating in binding GnRH has resulted in such perfection, that no substitution with a natural amino acid in any position improves binding potency.

14

Free intracellular calcium [(CA2plus)i] in opioid sensitive cells of the porcine anterior pituitary

84%

Szafranska B., Tilton J. E.

Journal of Physiology and Pharmacology

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2000

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tom 51

|

nr 3

15

Advances in reproductive endocrinology of fish

84%

Bieniarz K., Epler P.

Journal of Physiology and Pharmacology. Supplement

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1992

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tom 43

|

nr 1

16

The role of GABAa receptors in the neural systems of the medial preoptic area in the control of GnRH release during the luteal phase of the oestrous cycle in ewes

84%

Tomaszewska-Zaremba D., Mateusiak K., Przekop F.

Journal of Animal and Feed Sciences

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2004

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tom 13

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nr 1

17

The involvement of GABA A receptors in the control of GnRH and beta-endorphin release, and catecholaminergic activity in the ventromedial-infundibular region of hypothalamus in anestrous ewes

84%

Tomaszewska-Zaremba D., Przekop F., Mateusiak K.

Journal of Physiology and Pharmacology

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2001

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tom 52

|

nr 3

18

The role of GABAA receptors in the neural systems of the ventromedial-infundibular region of the hypothalamus in the control of gonadotropin release during the luteal phase in ewes

84%

Tomaszewska-Zaremba D., Mateusiak K., Przekop F.

Journal of Physiology and Pharmacology

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2002

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tom 53

|

nr 4,2

To examine the role of GABAA receptor mediating systems in the control of gonadotropin-releasing hormone (GnRH) release from the ventromedial- infundibular region (VEN/NI) in ewes during luteal phase, the extracellular concentrations of GnRH, ß-endorphin, noradrenaline (NE), dopamine (DA), and their metabolites: MHPG and DOPAC were quantified by local stimulation or blockade of GABAA receptors with muscimol or bicuculline, respectively. Stimulation of GABAA receptors in the VEN/NI did not affect GnRH, ß-endorphin release or catecholaminergic system activity. Blockade of GABAA receptors decreased ß-endorphinergic and dopaminergic activity, and lowered the extracellular concentration of MHPG. It did not affect GnRH release or luteinizing hormone (LH) secretion. It is suggested that progesterone-induced GABAergic activity during the luteal phase may desensitize GABAA receptors to muscimol. Lack of changes in GnRH/LH secretion with concomitant depressed ß-endorphinergic activity corroborated the conclusion that ß-endorphin does not inhibit GnRH release from the VEN/NI during the luteal phase. The physiological significance of changes in the catecholaminergic system activity under GABAA receptor blockade in the control of GnRH secretion awaits to be established.

19

Zmiany przepływu krwi przez narządy rozrodcze kury dojrzłej płciowo po podaniu hormonu uwalniającego gonadotropiny (Gn-RH)

67%

Niezgoda J., Wronska D., Bobek S., Pierzchala K., Sechman A.

Acta Agraria et Silvestria. Series Zootechnica

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1991

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tom 29

20

Diagnosing and management of iatrogenic moderate and severe ovarian hyperstymulation syndrome [OHSS] in clinical material

67%

Jakimiuk A. J., Fritz A., Grzybowski W., Walecka I., Lewandowski P.

Folia Histochemica et Cytobiologica. Supplement

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2007

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tom 45

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nr 1

105-108

Ograniczanie wyników

Does prolactin influence the hypothalamo-pituitary GnRH-LH system in preovulatory-phase ewes?

The role of GABAA and GABAB receptors in the control of GnRH release in anestrous ewes

Detection of gonadotropin-releasing hormone and somatostatin-14 containing cells in the mammary gland of guinea pigs

Serum progesterone concentrations on the day of oocyte retrieval above 9.23 ng/ml may predict ovarian hyperstimulation syndrome risk in in vitro fertilized patients

Molecular targets for immunocontraception

Modulation of anterior pituitary cell luteinizing hormone secretory activity by neuropeptide Y in early pregnant pigs

Effects of corticotropin releasing hormone and corticotropin releasing hormone antagonist on biosynthesis of gonadotropin releasing hormone and gonadotropin releasing hormone receptor in the hypothalamic-pituitary unit of follicular-phase ewes and contribution of kisspeptin

Artificial spawning of pikeperch (Sander lucioperca (L.)) stimulated with human chorionic gonadotropin (hCG) and mammalian GnRH analogue with a dopamine inhibitor

Vasopressin release from the rat hypothalamo-neurohypophysial system: effects of gonadotrophin-releasing hormone [GnRH], its analogues and melatonin

Gonadotropin-releasing hormone and kisspeptin-10 regulate nuclear receptor subfamily 5 group a member 1/catenin beta 1/nuclear receptor subfamily 0 group B member 1 activity in female rat anterior pituitary gland

The gonadotropins subunits, GNRH and GnRH receptor gene expression and role of carbon monoxide in seasonal breeding animals

Castration in male pigs: techniques and animal welfare issues

Evolution of gonadotropin-releasing hormone (GnRH) structure and its receptor

Free intracellular calcium [(CA2plus)i] in opioid sensitive cells of the porcine anterior pituitary

Advances in reproductive endocrinology of fish

The role of GABAa receptors in the neural systems of the medial preoptic area in the control of GnRH release during the luteal phase of the oestrous cycle in ewes

The involvement of GABA A receptors in the control of GnRH and beta-endorphin release, and catecholaminergic activity in the ventromedial-infundibular region of hypothalamus in anestrous ewes

The role of GABAA receptors in the neural systems of the ventromedial-infundibular region of the hypothalamus in the control of gonadotropin release during the luteal phase in ewes

Zmiany przepływu krwi przez narządy rozrodcze kury dojrzłej płciowo po podaniu hormonu uwalniającego gonadotropiny (Gn-RH)

Diagnosing and management of iatrogenic moderate and severe ovarian hyperstymulation syndrome [OHSS] in clinical material