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Cytotoxic and genotoxic activity of purine acyclic nucleotide analogs

100%

Otova B., Sladka M., Votruba I., Holy A., Schramlova J., Francova K.

Folia Histochemica et Cytobiologica. Supplement

1997

tom 35

nr 2

Daminozide - lack of the genotoxic activity in the short-term bacterial test

100%

Rahden-Staron I., Szumilo M., Ziemkiewicz P., Szymczyk-Wasiluk T.

Roczniki Państwowego Zakładu Higieny

1997

tom 48

nr 2

In the recent paper genotoxic effects of daminozide and its metabolites were tested. Evaluation of the mutagenic effect of daminozide was by: (i) the Salmonella/mammalian microsome Ames test with S.typhimurium TA97, TA98, TA100 and TA102. (ii) E. coli PQ37 strain to reveal an induction of the SOS response, (iii) S. typhimurium TA1538 (uvrB) and TA1978 (uvr+) to detect the chemicals bound covalently to DNA (repair test). Daminozide was not mutagenic in any of the S.typhimurium strains and did not induce damages in DNA recognized by correndonuclease II, as shown by the repair test. Only metabolites of daminozide induced the SOS system.

The effect of quercetin on induction of cytochrome P-450 studied by Cypia-test

67%

Czeczot H.

Acta Poloniae Toxicologica

1995

tom 03

nr 1

Ograniczanie wyników

1 Acta Poloniae Toxicologica

1 Folia Histochemica et Cytobiologica. Supplement

1 Roczniki Państwowego Zakładu Higieny

1 Czeczot H.

1 Francova K.

1 Holy A.

1 Otova B.

1 Rahden-Staron I.

1 Schramlova J.

1 Sladka M.

1 Szumilo M.

1 Szymczyk-Wasiluk T.

1 Votruba I.

1 Ziemkiewicz P.

2 1997

1 1995

Wyniki wyszukiwania

Cytotoxic and genotoxic activity of purine acyclic nucleotide analogs

Daminozide - lack of the genotoxic activity in the short-term bacterial test

The effect of quercetin on induction of cytochrome P-450 studied by Cypia-test