Wyniki wyszukiwania - AGRO

1

cAMP-dependent protein kinase: structural basis for function, regulation, and subcellular localization

100%

Taylor S. S., Narayana N., Huang L., Banky P., Wang L., Cheng X.

Cellular and Molecular Biology Letters

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1998

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tom 03

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nr 3

2

A comparison of adrenal gland function in lactating dairy cows with or without ovarian follicular cysts

75%

Silvia W. J., McGinnis A. S., Hatler T. B.

Reproductive Biology

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2005

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tom 05

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nr 1

3

Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik

Genetic predisposition to breast and/or ovarian cancer – focus on the candidate BARD1 gene

75%

Klonowska K., Ratajska M., Wojciechowska M., Kozlowski P.

BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology

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2014

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tom 95

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nr 3

4

Insulin-like growth factor 1

75%

Gronek P., Rychlewski T., Slomski R., Stankiewicz K., Lehmann J.

Studies in Physical Culture and Tourism

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2005

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tom 12

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nr 1

5

The morphology and function of the quadrate ligament

75%

Tubbs R. S., Shoja M. M., Khaki A. A., Lyerly M., Loukas M., O'Neil J. T., Salter E. G., Oakes W. J.

Folia Morphologica

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2006

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tom 65

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nr 3

225-227

There is a paucity of information in the literature regarding the quadrate ligament and the information that does exist is extremely conflicting. We dissected 30 cadavers (60 sides) to determine the morphology and function of this enigmatic ligament. A quadrate ligament (thickening of the elbow joint capsule) was found in all specimens. In all specimens this band was distinct from the circumferential fibres of the annular ligament. The length, width, and thickness of the quadrate ligament were found to be 11 mm, 8 mm, and 1 mm respectively. This ligament not only aided in securing the neck of the radius to the ulna but also resisted excessive supination and, to a lesser degree, pronation of the forearm. Following transection of the quadrate ligament, the head of the radius was secured to the ulna considerably less firmly and supination and pronation increased by 10 to 20 degrees and 5 to 8 degrees respectively. The quadrate ligament contributes to proximal radioulnar stability, limits the “spin” of this joint, and should be considered in manipulation, surgery, or imaging of the proximal forearm.

6

Analysis and characterisation of protein kinase inhibitor selectivity and function

75%

Daub H.

Cellular and Molecular Biology Letters

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2005

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tom 10

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nr Suppl.2

7

The cell-free protein biosynthesis - applications and analysis of the system

75%

Lamla T., Mammeri K., Erdmann V. A.

Acta Biochimica Polonica

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2001

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tom 48

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nr 2

The in vitro protein biosynthesis has the potentials to be come a powerful technology for biochemical research. Beside the determination of structure and function the in vitro evolution of proteins is also of great interest. The system described was used to produce bo vine heart fatty acid binding protein (FABP) and bacterial chloramphenicol acetyltransferase (CAT) with and with out fusion of the Strep-tag II af fin ity pep tide. The proteins were purified after and during protein biosynthesis by using a StrepTactin Sepharose matrix. No significant influence of the Strep-tag and the conditions during the af fin ity chro ma tog ra phy on mat lira tion or activity of the protein was observed. The in vitro evolution of proteins is feasible by means of ribosome display. The selection of a specific mRNA coding for a short ened FABP with a N-terminal His-tag via the accompanying protein property was shown. Goal of the selection was to bind the FABP via the His-tag on Ni(II)-IDA-agarose. Af ter nine cy cles of tran scrip tion, trans la tion, affinity selection and RT-PCR the protein with the His-tag could be enriched 108-fold. In or der to cor re late a pos si ble re la tion ship be tween changes in pro tein pop u la tion and bi o log i cal func tion stud ies were ini ti ated in which 2-dimensional pro tein pat terns of the to tal in vitro sys tem were com pared af ter 0 and 2 h re ac tion time. The very in ter- esting findings are that a number of proteins disappear, while others are newly formed dur ing protein synthesis.

8

Cytoskeletal proteins in heart muscle

75%

Pinder J. C., Taylor-Harris P. M., Hayes N. V. L., Gascard P. D., Maggs A. M., Baines A. J.

Cellular and Molecular Biology Letters

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2001

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tom 06

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nr 2

9

Structure, regulation and function of PKB-Akt - a major therapeutic target

75%

Hemmings B. A.

Cellular and Molecular Biology Letters

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2003

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tom 08

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nr 2A

10

Analysis of multidimensional digital images in fluorescence and confocal microscopy

75%

Dobrucki J. W.

Cellular and Molecular Biology Letters

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2002

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tom 07

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nr Suppl.

11

Dynamin: characteristics, mechanism of action and function

63%

Wiejak J., Wyroba E.

Cellular and Molecular Biology Letters

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2002

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tom 07

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nr 4

Dynamin - a member of the GTP-ase protein family - is essential for many intracellular membrane trafficking events in multiple endocytic processes. The unique biochemical features of dynamin - especially its propensity to assemble - enable severing the nascent vesicles from the membrane. The mechanism of dynamin’s action is still a subject of debate - whether it functions as a mechanochemical enzyme or a regulatory GTPase. The GTPase domain of dynamin contains three GTP-binding motifs. This domain is very conservative across the species, including that recently cloned by us in the unicellular eukaryote Paramecium. Dynamin interacts with a number of partners such as endophilin and proteins involved in coordination of endocytosis with motor molecules. A growing body of evidence indicates that dynamin and dynamin-related proteins are involved both in pathology and protection against human diseases. The most interesting are dynamin-like Mx proteins exhibiting antiviral activity.

12

Structure and function of bacterioplankton in the rehabilitated Lake Trzesiecko

63%

Lewicka-Rataj K., Kaczorkiewicz M., Heese T., Wasiniewska M., Miszczyn M.

International Journal of Ecohydrology and Hydrobiology

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2014

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tom 14

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nr 1

13

Structure and function of yolk nuclei in oocytes of salticid spiders

63%

Jedrzejowska I., Jankowska R.

Acta Biologica Cracoviensia. Series Botanica. Supplement

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2008

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tom 50

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nr 1

14

Thyroid and parathyroid function and structure in male rats chronically exposed to cadmium

63%

Pilat-Marcinkiewicz B., Brzoska M. M., Moniuszko-Jakoniuk J.

Polish Journal of Environmental Studies

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2008

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tom 17

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nr 1

113-120

The effect of exposure to cadmium (Cd) on the function and structure of the thyroid with parathyroids and a relationship between Cd accumulation in these glands and their damage were studied on a male rat model corresponding to human exposure. For this purpose, male rats were treated with Cd in drinking water at concentration of 5 and 50 mg Cd/dm³ for 12 and 24 weeks. The function of the thyroid was evaluated based on the measurement of serum concentrations of triiodothyronine (T₃) and tetraiodothyronine (T₄), and immunohistochemical identification of hormones such as calcitonin (CT), calcitonin-gene related peptide (CGRP) and somatostatin (ST). To assess the parathyroid function immunohistochemical reaction for parathyroid hormone-related peptide (PTHrP) was performed. Histological structure of the thyroid and parathyroid glands was evaluated in a light microscope. Rats exposed to 5 and 50 mg Cd/dm³ showed changes in the epithelium of follicular cells, intensified remodeling of the glandular structure of the thyroid, mononuclear cell infiltrations in connective tissue and pale staining of colloid. Hypertrophy and hyperplasia of endocrine parathyroid cells were evident.The intensity of reactions for CT, ST, CGRP and PTHrP was weakened. Exposure to Cd had no effect on the T₃ and T₄ serum concentrations, except for a marked increase in the concentrations of both hormones after 24 weeks of exposure to 50 mg Cd/dm³ . All the Cd-induced changes were much more advanced at exposure to 50 mg Cd/dm³ than 5 mg Cd/dm³ . The seriously disturbed structure and function of the thyroid and parathyroids at a low Cd concentration (0.087 ± 0.005 µg/g) in these glands suggests that the damaging Cd influence may be due to its indirect rather than direct action. Based on the results it can be hypothesized that a human body chronically exposed to moderate and relatively high Cd levels may be at risk of damage to the thyroid and parathyroid glands.

15

Structure and function of intersubunit bridges in procaryotic ribosome

63%

Kietrys A. M., Szopa A., Bakowska-Zywicka K.

Biotechnologia

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2009

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nr 1

48-58

16

Urban road network. The realization of the various functions of public space

63%

Bolimowska K.

Intercathedra

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2012

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tom 28

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nr 3

The sustainable development of a town is mainly the management of public space. The streets of the city, unlike the roads out of town, are not only a transport network. This is public good with many features. The subject of research is the use of street space and defining the needs of its users. The following analysis of the subject discusses the status of the network of streets of Poznan, selected functions of the road, the dynamics of the needs of road users. The urban street is becoming increasingly a place for meetings, events. Expectations as to the status of aesthetics, technical features and equipment of roads are growing. In some areas some people are going to slow down traffic, and even close streets for vehicles, while at the same time there is an ongoing fight against traffic congestion. The increase in complexity of urban road functions tends to redefine the network of streets towards public space.

17

Polyphenol-protein complexes and their consequences for the redox activity, structure and function of honey. A current view and new hypothesis - a review

63%

Brudzynski K., Maldonado-Alvarez L.

Polish Journal of Food and Nutrition Sciences

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2015

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tom 65

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nr 2

There is increasing evidence that protein complexation by honey polyphenols is changing honey structure and function. This relatively less investigated filed of honey research is presented in a context of known mechanism of formation of the stable polyphenol-protein complexes in other foods. At a core of these interactions lies the ability of polyphenols to form non-covalent and covalent bonds with proteins leading to transient and/or irreversible complexes, respectively. Honey storage and thermal processing induces non-enzymatic oxidation of polyphenols to reactive quinones and enables them to form covalent bonds with proteins. In this short review, we present data from our laboratory on previously unrecognized types of protein-polyphenol complexes that differed in size, stoichiometry, and antioxidant capacities, and the implications they have to honey antioxidant and antibacterial activities. Our intent is to provide a current understanding of protein-polyphenol complexation in honey and also some new thoughts /hypotheses that can be useful in directing future research.

18

Influence of phospho-gluco-peptides on the structure and function of the digestive tract in broiler chickens

63%

Szymanczyk S. E., Valverde P. J. L., Skrzypek T., Godlewski M., Skrzypek H., Biernat M., Zabielski R., Pierzynowski S. G.

Polish Journal of Natural Sciences. Supplement

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2006

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tom 03

531-539

19

Structure and functions of tumor necrosis factor-alpha converting enzyme

63%

Mezyk R., Bzowska M., Bereta J.

Acta Biochimica Polonica

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2003

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tom 50

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nr 3

Tumor necrosis factor-a converting enzyme (TACE) is the first described and best characterized secretase. In this review the structure and the possible roles for TACE are summarized. The substrate specificity and the regulation of TACE activity as well as redundancy and possible cooperations of distinct secretases are also discussed.

20

Plant metallothionein genes: structure, regulation and function in metal tolerance

63%

Goldsbrough P., Bundithya W., Orczyk W., Zhou J.

Biological Bulletin of Poznań. Supplement

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1997

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tom 34

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