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Juniperus communis L. (Cupressaceae) is a plant widely cultivated in the Northern hemisphere. Juniper berries, the fruit of Juniperus communis L. are a highly valued, essential oil-rich plant material used traditionally in folk medicine as antiseptic, diuretic, antirheumatic, anti-inflammatory, antibacterial and antifungicidal agent. This paper reviews information on extraction methods of the essential oil from the juniper berries, its chemical composition and antimicrobial as well as antioxidant properties.
Twinflower (Linnaea borealis L.) is a widespread circumboreal plant species belonging to Linnaeaceae family (previously Caprifoliaceae). L. borealis commonly grows in taiga and tundra. In some countries in Europe, including Poland, twinflower is protected as a glacial relict. Chemical composition of this species is not well known, however in folk medicine of Scandinavian countries, L. borealis has a long tradition as a cure for skin diseases and rheumatism. It is suggested that twinflower has potential medicinal properties. The new study on lead secondary metabolites responsible for biological activity are necessary. This short review summarizes very sparse knowledge on twinflower: its biology, distribution, conservation status, chemical constituents, and describes the role of this plant in folk tradition of Scandinavian countries.
In August 2015, twig blight disease of ban tulsi (Croton bonplandianus Bail.) caused by Choanephora cucurbitarum (Berk. & Ravenel) Thaxt. was observed for the first time, in the Gangetic alluvial region of West Bengal, India. A severe disease incidence (40–50%) showed twig blight symptoms starting with shoot apical meristem (SAM), leaf, and blossom blight symptoms. Typical symptoms were characterized by over-projecting black pin head like emerging sporangiola which formed mycelial cushion on the infected surface. The present report describes the identification of the causal pathogen as C. cucurbitarum based on its morphology and the internal transcribed spacer of its ribosomal DNA (rDNA – ITS) sequences with 100% identity of NCBI-GenBank published Choanephora database. Optimum temperatures, 28–30°C, coupled with high relative humidity (80–90%) during the monsoon season enhances the disease’s progress. To the best of our knowledge this is the first report of twig blight of C. bonplandianus, caused by C. cucurbitarum, in India as well as globally.
Angiogenesis, the formation of new capillaries from pre-existing vascular network, plays an important role in physiological and pathological processes such as embryonic development, wound healing, and development of atherosclerosis. Extension of the circulatory network is also considered to be one the most important factors during cancerogenesis. Inhibition of angiogenesis may lead to inhibition of tumor growth whereas stimulation may improve wound healing. Research achievements suggest the use of plants and their extracts as potential therapeutic agents with pro- or antiangiogenic activity. Since the anticancer and antiangiogenic properties of many phytomedicines have been amply reviewed elsewhere this paper will focus on the treatment of vascular insufficiency in wound healing. Globally accepted herbal drugs are thought to be safe and effective, however, there is a need for more evidence-based confirmation in controlled and validated trials. Among the most frequently studied proangiogenic phytochemicals are ginsenosides from Panax ginseng, beta-sitosterol from Aloe vera, calycosin from Radix Astragali, and extracts from Hippophae rhamnoides L. and Angelica sinensis.
Plant latex has many health benefits and has been used in folk medicine. In this study, the biological effect of Artocarpus heterophyllus (jackfruit) latex on human blood coagulation was investigated. By a combination of heat precipitation and ion-exchange chromatography, a heat stable heteromultimeric glycoprotein (HSGPL1) was purified from jackfruit milky latex. The apparent molecular masses of the monomeric proteins on SDS/PAGE were 33, 31 and 29 kDa. The isoelectric points (pIs) of the monomers were 6.63, 6.63 and 6.93, respectively. Glycosylation and deglycosylation tests confirmed that each subunit of HSGPL1 formed the native multimer by sugar-based interaction. Moreover, the multimer of HSGPL1 also resisted 2-mercaptoethanol action. Peptide mass fingerprint analysis indicated that HSGPL1 was a complex protein related to Hsps/chaperones. HSGPL1 has an effect on intrinsic pathways of the human blood coagulation system by significantly prolonging the activated partial thrombin time (APTT). In contrast, it has no effect on the human extrinsic blood coagulation system using the prothrombin time (PT) test. The prolonged APTT resulted from the serine protease inhibitor property of HSGPL1, since it reduced activity of human blood coagulation factors XIa and α-XIIa.
The centuries-old experience of folk medicine, nutritional traditions, and the results of numerous research studies show that plants of the genus Plantago can be used for medicinal, cosmetic, dietetic, and ritual purposes. In the phytochemical composition of Plantago, there is an abundance of biologically active substances (among others, glycosides, flavonoids, polysaccharides, and vitamins) exhibiting beneficial effects and, simultaneously, there is a low content of compounds that may exert a toxic effect. Scientific research has confirmed that Plantago plants have antioxidative, apoptosis-inhibiting, protective, healing-enhancing, spasmolytic, anthelmintic, and antimicrobial properties; they inhibit the development of some tumours, reduce the level of lipids in blood and inhibit tissue glycation. In phytotherapy, leaves, stems, and/or seeds of different plantain species are used. Plantago leaves and seeds are also used to manufacture creams, lotions, and face masks. Different parts of these plants (fresh plant material, extracts, or isolated substances) are also used in human and animal nutrition. Plantain leaves can be eaten like lettuce or added to salads, fried in pastry, used to prepare a tea, juice, or wine. Its seeds are added to cakes, bread, breakfast cereals, ice cream, and drinks, or they are cooked like groats. Animals fed with plantain can live longer and are healthier, while meat derived from such animals is tastier and healthier to humans. Plantago seeds are readily eaten by cage birds. Plantain pollen, produced in large amounts (up to 20,000 pollen grains per 1 stamen of P. lancolata), can cause allergies in sensitive people. Due to a long flowering period of plants of the genus Plantago, the effect of the allergenic factor persists for many weeks. In Poland days with the maximum concentration of airborne plantain pollen most often occur in July.
Trigonella foenum-graecum L.(Leguminosae), known in Morocco as “Helba”, is used in folk medicine for its anti-ulcer, anti-inflammatory, cicatrizing activities and to treat various pain-related physiological states. In present study, we attempted to verify the possible antinociceptive and anti-inflammatory activities of different extracts obtained from the seeds of this plant. Three experimental models were used (i.e. acetic acid, formalin, and hot-plate tests) in order to characterize both the analgesic and the anti inflammatory effects. Dichloromethane (350 and 500 mg/kg), ethyl acetate [(EAE) (350 and 500 mg/kg)], aqueous (500 mg/kg) and butanolic (500 mg/kg) extracts significantly and in a dose-dependent manner reduced the pain induced by IP injection of acetic acid. In the formalin test, the extracts, except EAE, significantly reduced the painful stimulus but only in the early phase of the test. On the contrary, these extracts, except EAE, were ineffective in increasing the latency of licking or jumping in the hot-plate test. These results suggest that the compounds present in the extracts activated both central and peripheral mechanisms to elicit the analgesic and anti-inflammatory effects. However, pharmacological and chemical studies are continued in order to characterize these mechanisms and also to identify the active principles present in each extract.
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