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1

Study of the hydromineral regulation of Typhlonectes compressicauda according to the seasonal variation

100%
Yousef M., Moudilou E. N., Djoudad-Kadji H., Exbrayat J.-M.
Folia Histochemica et Cytobiologica
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2018
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tom 56
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nr 3
2

Changes of the expression of Lewis blood group antigens in glycoproteins of renal cancer tissues

84%
Borzym-Kluczyk M., Radziejewska I.
Acta Biochimica Polonica
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2013
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tom 60
|
nr 2
 Sialic acid and sialyl Lewisa/x are found on N- and O-glycans of many human malignant cells. Carbohydrate antigens can be used as tumor markers, and an increase of their levels in cancer cells is associated with tumor progression. The aim of this study was to assess the level of some Lewis blood group antigens on glycoproteins in tumor (cancer tissue), intermediate zone (adjacent to tumor tissue), and normal renal cortex/medulla (uninvolved by tumor). The study was performed on tissues taken from 30 patients. Relative amounts of sugar structures of proteins with molecular masses above 30 kDa were determined by ELISA-like test with biotinylated lectins: MAA (Maackia amurensis), SNA (Sambucus nigra), and monoclonal antibodies anti-sialyl Lewisa/x. Higher expression of all examined structures was revealed in cancer tissues. Significant increases were observed for sialic acid linked α 2-3 in cancer tissues when compared to healthy ones and also among intermediate and healthy tissues. The sialic acid linked α 2-6 and sialyl Lewisx structures were significantly increased in cancerous cells when compared to normal and intermediate renal tissue. In case of sialyl Lewisa antigen, a significant difference was discovered between normal and intermediate tissue. Our results confirm that the examined Lewis antigens can be involved in tumor development. Their increase in cancer tissues can suggest their specific role in the process.
3
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Trichinellosis in mice: changes in the expression of Toll-like receptor 4 (TLR4) during the intestinal phase of experimental trichinellosis

84%
Wojtkowiak-Giera A., Wandurska-Nowak E., Derda M., Hadas E., Lopaciuch J.
Annals of Parasitology
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2016
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tom 62
|
nr Suppl.
4

Changes in expression of pRb, p16 and cyclin D1 in non-small cell lung cancer: an immunohistochemical study

84%
Malusecka E., Zborek A., Krzyzowska-Gruca S.
Folia Histochemica et Cytobiologica
|
1999
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tom 37
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nr 1
5

Expression changes of bovine leukaemia virus genes under the impact of tyrosine kinase inhibitors - geldanamycin and tyrphostin

84%
Grabek-Gawlowicz M., Rulka J., Gawlowicz J., Marzec B., Kubiatowski T., Filip A., Koczkodaj D., Wojcierowski J.
Bulletin of the Veterinary Institute in Puławy
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2003
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tom 47
|
nr 2
6

Expression changes of estrogen receptors alpha and beta in testis and epididymis of male mice under the influence of diet rich in phytoestrogens

67%
Sliwa L., Macura A. B.
Acta Biologica Cracoviensia. Series Botanica. Supplement
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2008
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tom 50
|
nr 1
7

MCP-1, ICAM-1 and VCAM-1 are present in early aneurysmal dilatation in experimental rats

67%
Fan J., Li X., Zhong L., Tong H., Di J., Liu F., Zhao H.-H., Bai S.-L.
Folia Histochemica et Cytobiologica
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2010
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tom 48
|
nr 3
8

Changes in the expression of tyrosine hydroxylase [TH], dopamine beta-hydroxylase [DBH], galanin [GAL], vasoactive intestinal polypeptide [VIP] and substance P [SP] in the uterine cervix-projecting neurons located in the lumbar paravertebral ganglia of the pig

67%
Wasowicz K.
Folia Morphologica
|
2003
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tom 62
|
nr 3
219-221
The uterine cervix-projecting neurons located in the lumbar paravertebral ganglia were identified by retrograde tracing. These contained immunoreactivity to TH and DBH. No immunoreactivity to GAL, VIP and SP was found in the neurons. Extirpation of the uterus reduced the expression of TH and induced the expression of GAL in the neurons. Expression of other substances studied was unchanged.
9

Monobutyl phthalate induces the expression change of G-protein-coupled receptor 30 in rat testicular Sertoli cells

67%
Hu Y., Li D., Lu Y., Han X.
Folia Histochemica et Cytobiologica
|
2013
|
tom 51
|
nr 1
10

Changes in expression of serine proteases HtrA1 and HtrA2 during estrogen-induced oxidative stress and nephrocarcinogenesis in male Syrian hamster

67%
Zurawa-Janicka D., Kobiela J., Stefaniak T., Wozniak A., Narkiewicz J., Wozniak M., Limon J., Lipinska B.
Acta Biochimica Polonica
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2008
|
tom 55
|
nr 1
Serine proteases HtrA1 and HtrA2 are involved in cellular stress response and development of several diseases, including cancer. Our aim was to examine the involvement of the HtrA proteins in acute oxidative stress response induced in hamster kidney by estrogen treatment, and in nephrocarcinogenesis caused by prolonged estrogenization of male Syrian hamster. We used semi-quantitative RT-PCR to estimate the HtrA1 and HtrA2 mRNA levels in kidney tissues, and Western blotting to monitor the amount of the HtrA proteins. Within the first five hours following estrogen administration both HtrA1 mRNA and the protein levels were increased significantly. No changes in the expression of HtrA2 were observed. This indicates that HtrA1 may be involved in the response against oxidative stress induced by estrogen treatment in hamster kidney. During prolonged estrogenization, a significant reduction of the HtrA1 mRNA and protein levels was observed after 6 months of estradiol treatment, while the expression of HtrA2 was significantly elevated starting from the third month. This suggests an involvement of the HtrA proteins in estrogen-induced nephrocarcinogenesis in hamster. Using fluorescence in situ hybridization we localized the HtrA1 gene at the qb3-4 region of Syrian hamster chromosome 2, the region known to undergo a nonrandom deletion upon prolonged estrogenization. It is possible that the reduced level of HtrA1 expression is due to this chromosomal aberration. A full-length cDNA sequence of the hamster HtrA1 gene was obtained. It codes for a 50 kDa protein which has 98 and 96% identity with mouse and human counterparts, respectively.
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