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Inheritance of colours in horses

100%

Stachurska A.

Journal of Applied Genetics

1997

tom 38

nr 2

The inheritance of colour in horses had been investigated for many years but since Adalsteinsson’s findings on basic and diluted colours, made in the seventies, opinions have changed considerably. Many authors supported this hypothesis by detailed breeding and laboratory experiences. This article contains a review of the most important publications concerning the mode of inheritance of all known horse colours. Some of the papers were published long ago but are still valid. The role of different loci determining horse colour is discussed in relation to other mammals and to the current knowledge on melanogenesis. The paper presents references for 14 loci responsible for horse coat colour.

Splenic aumelanin differs from hair eumelanin in C57BL-6 mice

84%

Plonka P. M., Michalczyk D., Popik M., Handjiski B., Slominski A., Paus R.

Acta Biochimica Polonica

2005

tom 52

nr 2

The presence of melanin in spleens of black C57BL/6 mice has been known for long. Although its origin and biological functions are still obscure, the relation of splenic melanin to the hair follicle and skin pigmentation was suggested. Here, we demonstrated using for the first time electron paramagnetic resonance spectroscopy that black-spotted C57BL/6 spleens contain eumelanin. Its presence here is a “yes or no” phenomenon, as even in the groups which revealed the highest percentage of spots single organs completely devoid of the pigment were found. Percentage of the spotted spleens decreased, however, with the progress of telogen after spontaneously-induced hair growth. The paramagnetic properties of the spleen eumelanin differed from the hair shaft or anagen VI skin melanin. The splenic melanin revealed narrower signal, and its microwave power saturability betrayed more heterogenous population of paramagnetic centres than in the skin or hair shaft pigment. Interestingly, the pigment of dry hair shafts and of the wet tissue of depilated anagen VI skin revealed almost identical properties. The properties of splenic melanin better resembled the synthetic dopa melanin (water suspension, and to a lesser degree – powder sample) than the skin/hair melanin. All these findings may indicate a limited degradation of splenic melanin as compared to the skin/hair pigment. The splenic eumelanin may at least in part originate from the skin melanin phagocyted in catagen by the Langerhans cells or macrophages and transported to the organ.

Ograniczanie wyników

1 Acta Biochimica Polonica

1 Journal of Applied Genetics

1 Handjiski B.

1 Michalczyk D.

1 Paus R.

1 Plonka P. M.

1 Popik M.

1 Slominski A.

1 Stachurska A.

1 2005

1 1997

Wyniki wyszukiwania

Inheritance of colours in horses

Splenic aumelanin differs from hair eumelanin in C57BL-6 mice