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1

Effect of erythromycin treatment on specific immunologic response in mice

100%
Nicolas R., Amurrio C., Lewden S., Camarero M., Cisterna R.
Archivum Immunologiae et Therapiae Experimentalis
|
1989
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tom 37
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nr 3-4
2

The strongest resistance of Staphylococcus aureus to erythromycin is caused by decreasing uptake of the antibiotic into the cells

84%
Piatkowska E., Piatkowski J., Przondo-Mordarska A.
Cellular and Molecular Biology Letters
|
2012
|
tom 17
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nr 4
The consequence of excessive use of macrolides is a high occurrence of mechanisms responsible for resistance to these drugs. Of 97 erythromycin-resistant bacterial strains gathered in the Wrocław area in Poland, 60% exhibited very high resistance, and those with the inducible MLSB (macrolide-lincosamide-streptogramin B) resistance phenotype predominated. Direct genetic investigation revealed that the erm genes coding for ribosomal methylases are the most frequently occurring erythromycin resistance-determining genes. No genetic resistance determinant was detected in 13% of the erythromycin-resistant strains. The efflux mechanism occurs in strains isolated from the nasopharyngeal cavity twice as often as in those isolated from other material, where the mechanism connected with target site modification predominates. Measurements of radiolabelled antibiotic accumulation inside bacterial cells revealed that in highly resistant strains (MIC > 1024 μg/ml), an important factor responsible for the resistance is the permeability barrier at the cell wall level. This would be a hitherto unknown mechanism of resistance to erythromycin in Staphylococcus aureus.
3
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Molecular docking and pharmacokinetic prediction of phytochemicals from Syzygium cumini in interaction with penicillin-binding protein 2a and erythromycin ribosomal methylase of Staphylococcus aureus

84%
Shidiki A., Vyas A.
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
|
2022
|
tom 103
|
nr 1
4

The influence of selected antibiotics on aquatic microorganisms

84%
Miernik A., Rzeczycka M.
Polish Journal of Microbiology
|
2007
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tom 56
|
nr 4
This paper presents the influence of penicillin, erythromycin, Oxytetracycline and streptomycin on aquatic microorganisms isolated from three reservoirs with varied extent of environmental pollution (Sulejów Reservoir, Zegrze Reservoir and Vistula River). The experiments were conducted in especially prepared microcosms (aerated 15 l aquariums). From among the examined antibiotics streptomycin showed the longest activity in the water environment (27 days), followed by Oxytetracycline (22 days). Erythromycin had 13 days activity while the penicillin only 4 days. The highest number of bacteria was observed in the Vistula, fewer in Zegrze Reservoir. Sulejów Reservoir was characterized by the lowest number of bacteria. The strains isolated from Sulejów Reservoir were characterized by higher degree of biodiversity than those from Zegrze Reservoir or Vistula River. The dominant genera were Pseudomonas (49%), followed by Acinetohacter (21 %), Flavomonas (9%), Alcaligenes (9%), Vibrio, Moraxella and Oligella. The Vistula River was dominated by Aeromonas (88%) and Pseudomonas (12%) genera. The strains isolated from Sulejów Reservoir were more sensitive to antibiotics than those from the much more polluted Vistula, this being evidenced by lower MIC and MBC values.
5
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In vitro effect of sub-inhibitory concentrations of penicillin and erythromycin on Staphylococcus aureus

84%
Rozanska H., Wojton B.
Bulletin of the Veterinary Institute in Puławy
|
1998
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tom 42
|
nr 2
In vitro effect of sub-inhibitory concentrations of penicillin and erythromycin on the number, growth rate, and cultural and biochemical characteristics of Staphylococcus aureus was examined. A decreased number and a slow growth of Staph.aureus in broth and minced meat comprising selected concentrations of antibiotics, and alterations in enzymatic and biochemical activities were found.
6

Cholinergic control of pacemaker initiating phase III of the migrating myoelectric complex in sheep

84%
Romanski K. W., Slawuta P.
Journal of Animal and Feed Sciences
|
2002
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tom 11
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nr 4
7

Tetracycline, erythromycin, and gentamicin resistance of Campylobacter jejuni and Campylobacter coli isolated from poultry in Poland

67%
Wozniak A., Wieliczko A.
Bulletin of the Veterinary Institute in Puławy
|
2011
|
tom 55
|
nr 1
The aim of the research was the determination of resistance of 387 Campylobacter sp. strains isolated between 1994 and 1996 (broilers, laying hens) and 2005-2008 (broilers, laying hens, turkeys) to tetracycline, erythromycin, and gentamicin. The resistance was determined with the reference to minimum inhibitory concentration on the agar plates (MIC). Limit concentration value for tetracycline and gentamicin was measured at >8 µg/mL, while for erythromycin it was obtained at >16 µg/mL. Among the Campylobacter sp. isolates obtained in 2005-2008, tetracycline resistant strains were found, while the isolates obtained between 1994 and 1996 were tetracycline susceptible. An increase in the percentage of erythromycin intermediate susceptible strains from 2005- 2008 was reported in comparison to the isolates obtained in 1994-1996. Gentamicin susceptibility was found in 99.5% of all the Campylobacter sp. strains isolated between 1994 and 2008. These findings reveal a broad extent of antimicrobial resistance in Campylobacter isolates from poultry in Poland and underline the need for prudent use of antibiotics in poultry production to minimise the spread of antibiotic resistant Campylobacter strains.
8

First isolation of Clostridium difficile PCR-ribotype 027-toxinotype III in Poland

67%
Pituch H., Bakker D., Kuijper E., Obuch-Woszczatynski P., Wultanska D., Nurzynska G., Bielec A., Bar-Andziak E., Luczak M.
Polish Journal of Microbiology
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2008
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tom 57
|
nr 3
Of 175 Clostridium difficile strains isolated from patient hospitalized in one academic hospital in Warsaw between 2005-2006 one isolate belonged to PCR-ribotype 027/toxinotype III. This isolate had tcdA, tcdB, binary toxin genes (cdtA and cdtB), a 18-bp deletion and a 1 bp deletion at 117 position in the tcdC gene. Antimicrobial susceptibility tests revealed high level resistance to erythromycin, moxifloxacin and gatifloxacin. This is a first report of the 027 strain of C. difficile in Poland.
9

Characterization of glycopeptides, aminoglycosides and macrolide resistance among Enterococcus faecalis and Enterococcus faecium isolates from hospitals in Tehran

67%
Emaneini M., Aligholi M., Aminshahi M.
Polish Journal of Microbiology
|
2008
|
tom 57
|
nr 2
The prevalence of glycopeptides, aminoglycosides and erythromycin resistance among Enterococcus faecalis and Enterococcus faecium was investigated. The susceptibility of 326 enterococcal hospital isolates to amikacin, kanamycin, netilmicin and tobramycin were determined using disk diffusion method. The minimum inhibitory concentration (MIC) of vancomycin, teicoplanin, gentamicin, streptomycin, and erythromycin were determined by microbroth dilution method. The genes encoding aminoglycoside modifying enzymes described as AMEs genes, erythromycin-resistant methylase (erm) and vancomycin-resistant were targeted by multiplex-PCR reaction. High level resistance (HLR) to gentamicin and streptomycin among enterococci isolates were 52% and 72% respectively. The most prevalent of AMEs genes were aac (6')-Ie aph (2") (63%) followed by aph (3') -IIIa (37%). The erythromycin resistance was 45% and 41% of isolates were positive for ermB gene. The ermA gene was found in 5% of isolates whereas the ermC gene was not detected in any isolates. The prevalence of vancomycin resistant enterococci (VRE) was 12% consisting of E. faecalis (6%) and E. faecium (22%) and all of them were VanA Phenotype. The results demonstrated that AMEs, erm and van genes are common in enterococci isolated in Tehran. Furthermore our results show an increase in the rate of vancomycin resistance among enterococci isolates in Iran.
10
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Single infusion of an antibiotic with glucose and acetylsalicylic acid or chlormethine as a new method of subclinical mastitis treatment in cows in the lactation period

67%
Malinowski E.
Bulletin of the Veterinary Institute in Puławy
|
1992
|
tom 36
11

Mutagenesis and ultraviolet inactivation of transforming DNA of Haemophilus influenzae complexed with a Bacillus subtilis protein that alters DNA conformation

67%
Setlow J. K., Setlow B. C., Setlow P.
Acta Biochimica Polonica
|
1996
|
tom 43
|
nr 1
The wild-type Bacillus subtilis spore protein, SspCwt, binds to DNA in vitro and in vivo and changes the conformation of DNA from B to A. Synthesis of the cloned SspCwt gene in Escherichia coli also causes large increases in mutation frequency. Binding of SspCwt to transforming DNA from Haemophilus influenzae made the DNA resistant to ultraviolet (UV) radiation. The mutant protein, SspCala, which does not bind DNA, did not change the UV resistance. The UV sensitivity of the DNA/SspCwt complex was not increased when the recipients of the DNA were defective in excision of pyrimidine dimers. These data indicate that the H. influenzae excision mechanism does not operate on the spore photoproduct formed by UV irradiation of the complex. Selection for the streptomycin- or erythromycin-resistance markers on the transforming DNA evidenced significant mutations at loci closely linked to these, but not at other loci. SspCwt apparently entered the cell attached to the transforming DNA, and caused mutations in adjacent loci. The amount of such mutations decreased when the transforming DNA was UV irradiated, because UV unlinks linked markers.
12

Comparison of simple methods of methicillin- resistance detection and evaluation of some properties of methicillin-resistant Staphylococcus aureus strains

67%
Trzcinski K., Zareba T., Tyski S., Hryniewicz W.
Acta Microbiologica Polonica
|
1993
|
tom 42
|
nr 1
13

Antibiotic resistance of Campylobacter jejuni with reference to plasmid profiles of clinical and chicken isolates

67%
Lekowska-Kochaniak A., Rozynek E., Popowski J.
Acta Microbiologica Polonica
|
1996
|
tom 45
|
nr 3-4
14

Monitoring of susceptibility of Helicobacter pylori to antimicrobial agents using E-tests

67%
Andrzejewska E., Klincewicz H.
Journal of Physiology and Pharmacology. Supplement
|
1997
|
tom 48
|
nr 1
15
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Content available

Susceptibility of Helicobacter pylori to antimicrobial agents : effect of ebrotidine and ranitidine

59%
Piotrowski J., Piotrowski E., Slomiany A., Slomiany B. L.
Journal of Physiology and Pharmacology
|
1995
|
tom 46
|
nr 4
16
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

Effect of acetylsalicylic acid and chlormethine on the minimum inhibitory concentration of antibiotics for organisms causing mastitis in cows

51%
Malinowski E.
Bulletin of the Veterinary Institute in Puławy
|
1993
|
tom 37
|
nr 2
17
Artykuł dostępny w postaci pełnego tekstu - kliknij by otworzyć plik
Content available

Effect of the combination of acetylsalicylic acid or chlormethine with antibiotics and glucose on the mammary gland of healthy cows

51%
Malinowski E.
Bulletin of the Veterinary Institute in Puławy
|
1992
|
tom 36
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