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The risk of overweight and obesity in chronic diseases among Warsaw inhabitants measured by self-reported method

100%

Supranowicz P., Wysocki M. J., Car J., Debska A., Gebska-Kuczerowska A., Gromulska L.

Roczniki Państwowego Zakładu Higieny

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2013

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tom 64

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nr 3

Background. Obesity is well known cause of various diseases. However, there are only a few studies which enable to compare directly the magnitude of risk in different groups of chronic diseases. Objectives. The aim of presented paper was to identify a magnitude of the risk of chronic diseases attributable to overweight and obesity on the basis of data on weight and height self-reported by respondents. Material and methods. The survey was conducted among 402 Warsaw inhabitants selected by non-random method. Overweight and obesity was measured by Body Mass Index (BMI) on the basis of the data of weight and height reported by respondents. According to WHO criteria the normal weight is defined as BMI 18.5 - 24.9 kg/m2, overweight as BMI 25.0 - 29.9 kg/m2, and obesity as BMI 30 kg/m2 or more. The following groups of chronic diseases were included: cancer, diabetes and other endocrine diseases, mental disorders, cardiovascular diseases, respiratory diseases, digestive diseases, arthritis and allergy disorder. Results. Obesity measured by self-reported method was recognised as significant risk factor for diabetes (OR=9.6, Cl: 2.0152.8), respiratory diseases (OR=10.6, Cl: 3,0-333,7), cardiovascular diseases (OR=5.2, Cl: 1.9-108.3), arthritis (OR=6.3, Cl: 2.4-266.7), digestive diseases (OR=3,8, Cl: 1.3-83.6) and mental disorders (OR=5.8, Cl: 1.5-29.1), while overweight significantly increased the risk of diabetes (OR=4.4, Cl: 1.2-10.8), respiratory diseases (OR=3.2, Cl: 1.4-22.2), cardiovas- culardiseases (OR=2.9, Cl: 1.2-6.4) andarthritis (OR=3.0, Cl: 1.1-9.6) Conclusions. Our findings showed that data on weight and height collected by survey method provide some information about the magnitude of the risk regarding particular groups of diseases attributable to overweight and obesity, nevertheless, underestimation ofBMI calculated in this way should be taken into account.

2

Sperm epigenetic profile and risk of cancer

100%

Wdowiak A.

Journal of Pre-Clinical and Clinical Research

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2014

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tom 08

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nr 2

Introduction and objective. The integrity, stability and composition of sperm chromatin are of great importance in the fertilizing potential of male gametes and their capacity to support normal embryonic development. In this study, the author presents the current state of knowledge about the sperm epigenetic profile and risk of cancer. Abbreviated description of the state of knowledge. The obtaining of pregnancy and the state of health of the baby depends on the quality of the genetic material of both the female and the male. Health behaviours and environmental factors directly affect the quality of sperm, as well as the human egg cell and, consequently, on the reproductive capabilities, the course of pregnancy and the state of the newborn. There exist two thoroughly investigated epigenetic modifications: DNA methylation and histone modifications. The process of DNA methylation can be also a fundamental factor contributing to the development of cancer, where epigenotype undergoes significant modifications. When considering numerous DNA aberrations in the male gamete, the most commonly encountered is DNA fragmentation, particularly in infertile subjects. Surprisingly, an intracytoplasmatic sperm injection study of mice oocytes, using spermatozoa with a high DNA Fragmentation Index (DFI), revealed that a considerable percentage of adults born as a result of this method, showed a significant increase in the incidence of abnormal behavioural tests, malformations, cancer and signs of premature aging. Summary. The issue of assisted procreation raises the need to look for an appropriate treatment for males with sperm chromatin abnormalities. As a result, the fight against smoking addiction becomes the obvious necessity. Moreover, the reasonable solution nowadays seems to be supplementation with micronutrients and folic acid. It has been proved that the process of DNA fragmentation is a phenomenon that intensifies over time. Therefore, there should be a pursuance for, as close as possible, to the moment of ejaculation, application of semen to reproductive techniques. Finally, epigenetic changes are suspected of being one of the factors responsible for the deterioration of male sperm parameters observed in recent decades.

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Coffee consumption vs. cancer risk - a review of scientific data

100%

Wierzejska R.

Roczniki Państwowego Zakładu Higieny

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2015

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tom 66

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nr 4

Coffee and its impact on health continue to be the topic of much heated debate. Until recently, coffee consumption has been believed to be associated with adverse effects, mainly cardiovascular problems. However, the vast majority of contemporary sources not only emphasize a lack of detrimental effect, but also suggest a beneficial effect of coffee intake. According to the current state of knowledge, coffee consumption is not associated with the majority of cancers although the results of studies on bladder and lung cancer remain conflicting. In case of colorectal, liver and breast cancers, coffee drinking may even have a protective effect. Coffee contains numerous compounds, potentially beneficial as well as harmful. The former include polyphenols which inhibit harmful oxidation processes in the body, while the latter include acrylamide, whose high intake in daily diet may have carcinogenic action. The impact of coffee on the human body is associated also with other factors, e.g. the rate of metabolism and other individual features.

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National Cholesterol Prevention Programme (NCPP) in Poland - methods and expectations

100%

Cybulska B., Szostak W. B., Sznajd J.

Żywienie Człowieka i Metabolizm

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1988

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tom 15

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nr 4

Polska spośród wszystkich krajów rozwiniętych wykazuje najwyższy wzrost umieralności na chorobę niedokrwienną serca (IHD) i choroby naczyń mózgowych. Jest to związane z rozpowszechnieniem czynników ryzyka IHD, a wśród nich podwyższonego poziomu cholesterolu w surowicy i nadwagi. Oba te czynniki zależą w istotnym stopniu od nieprawidłowego żywienia. Świadomość pilnej potrzeby podjęcia działań profilaktycznych spowodowała powołanie Narodowego Programu Profilaktyki Cholesterolowej, za którego realizację resort zdrowia uczynił odpowiedzialny Instytut Żywności i Żywienia. Na Program składają się następujące działania: 1. Popularyzacja na skalę społeczną wiedzy na temat szkodliwych następstw podwyższonego poziomu cholesterolu oraz roli racjonalnego żywienia w profilaktyce IHD. 2. Szkolenie przed- i podyplomowe lekarzy na powyższy temat. 3. Organizacyjne usprawnienie wczesnej diagnostyki podwyższonych stężeń cholesterolu. 4. Podjęcie wysiłków na rzecz nowoczesnej polityki wyżywienia w Polsce. 5. Udoskonalenie metod leczenia zaburzeń gospodarki lipidowej i ich upowszechnienie.

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Workplace health threats and their effects in Podlasie Region

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Zalewska M., Walamaniuk M., Pawinska M., Szpak A., Huzarska D., Komorowska E.

Polish Journal of Environmental Studies

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2008

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tom 17

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nr 5

797-800

Workplace health threats bring with them the risk of occupational diseases and work accidents [1-4]. The aim of this study was to describe the main health threats emerging from working conditions in the Podlasie region and to compare these outcomes with the overall situation in Poland. This paper describes the analysis of the structure of occupational diseases and accidents in Podlasie. The analysis was performed based on the data gathered by the Main Statistical Office (GUS), National Labour Inspectorate (PIP) and Regional Labour Inspectorate in Białystok (OIP), Podlasie Voivodship Labour Medicine Centre (PWOMP) and Voivodship Sanitary Inspectorate in Białystok (WSSE). Furthermore, a review of legal acts and literature has been performed. The results indicate that the main group of occupational diseases in Podlasie is contagious and parasitic diseases, among them borreliosis (over 70%). In Poland the main problem is long-term glottis disease, emerging from repeated speaking of teachers. It was the result of lack of medical and educational prophylaxis concerning voice emission. The highest number of occupational accidents in 2005 in Podlasie region was observed in trade – similar to Poland overall. Observed occupational accidents were related with workers with the shortest work experience (less than 1 year) – about 30% of victims. The following conclusions were drawn based on the above-mentioned results: 1. The biggest problem in Podlasie is the presence of contagious and parasitic diseases; the high borreliosis incidences which belong to this group are related to farmers and foresters. 2. The main cause of occupational diseases in Podlasie region was workers’ misbehaviour. Trade workers were the main group of occupational accident victims in Podlasie. Most often the least experienced workers were injured.

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Sposob zywienia mlodziezy w Polsce na podstawie pismiennictwa z ostatnich 10 lat [1990-2000]

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Augustyniak U., Brzozowska A.

Roczniki Państwowego Zakładu Higieny

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2002

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tom 53

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nr 4

399-406

Analiza danych z piśmiennictwa z ostatnich 10 lat, dotyczących oceny sposobu odżywiania młodzieży wykazała wiele nieprawidłowości, co może mieć wpływ na zwiększenie ryzyka wystąpienia chorób na tle wadliwego żywienia w późniejszym okresie życia.

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The influence of body mass on some coronary risk factors in the population of metallurgy workers

84%

Gudowska-Nitka A.

Żywienie Człowieka i Metabolizm

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1990

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tom 17

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nr 2

Food intake, body mass index (BMI), serum lipids, blood glucose, systolic and diastolic blood pressure and pulse wave velocity were measured in the population of 2559 males aged 25-59 years employed in a foundry in Cracow in 1972-1974. Abnormal dietary habits were revealed. The share of protein in total energy intake was 11.7%, fats 37.1% and carbohydrates 51.2% (sugar 11.6%). The mean BMI was 25.3 ± 3.1 BMI above 25 was found in 44% of males under study. It has been shown that serum cholesterol, total lipids, esterified fatty acids, systolic and diastolic blood pressure, and pulse wave velocity were positively correlated with BMI. It is concluded that obesity prevention and treatment should be recognized as. an important method in prevention of coronary heart disease.

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Effect of probiotic supplementation on liver function and lipid status in rats

84%

Skrypnik K., Bogdanski P., Loniewski I., Regula J., Suliburska J.

Acta Scientiarum Polonorum. Technologia Alimentaria

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2018

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tom 17

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nr 2

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Energy and nutritional value of the meals in kindergartens in Nis (Serbia)

84%

Lazarevic K., Stojanovic D., Bogdanovic D.

Roczniki Państwowego Zakładu Higieny

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2014

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tom 65

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nr 2

Background. It is well known that high-energy diet, rich in fat and carbohydrates, increases the risk of obesity. Preschool age is an important period to acquire the eating habits continued later in adulthood. Therefore, evaluation of child nutrition in kindergartens is especially important in the prevention of future obesity. Objectives. To determine the energy value and energy density of meals consumed by children in kindergartens in Niš (Serbia), including the different types of food, in respect to a probable risk of obesity. Material and methods. The study had been conducted in the years 1998-2012. Three-hundred samples of the meals were gathered and analysed, and the amount of selected food groups used to prepare the meals in kindergartens was calculated (weight, protein, fat and carbohydrate content) in the accredited laboratory of the Public Health Institute in Niš according to the ISO 17025 recommendation. Results. The mean energy value of meals was 978.9 kcal (range: 810 – 1144 kcal). The energy density was low (mean: 1.02 kcal/g, range: 0.92 – 1.42 kcal/g) and decreased over the years, what would imply a reduction in the risk of obesity. The intake of same high-energy food products, such as fats and oils as well as sweets (13,9% and 7,3%, respectively) was higher compared to low-energy foods (fruits – 5.2% and vegetables – 10.8%). Conclusions. The results of our study indicate that children in kindergarten in Niš, in general, were properly nourished in total energy content. The energy value and energy density of the meals consumed did not pose a risk of developing obesity. However, the distribution of food groups differentiated by the energy density level was unfavourable; the deficit of low-energy foods was observed. Planning the child nutrition in kindergartens, with laboratory control of meals, may be an effective strategy in adequate energy intake and prevention of obesity. Providing the higher amount of low-energy foods (fruits and vegetables) in meals in kindergartens is recommended.

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Acrylamide levels in food in Poland

84%

Mojska H., Gielecinska I., Stos K., Jarosz M.

Żywienie Człowieka i Metabolizm

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2010

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tom 37

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nr 2

The objective of our study was to determine acrylamide level in foods randomly taken from all over Poland in 2007 according to the Commission Recommendation (2007/331/EC). We analysed the acrylamide level using GCQ-MS/MS method. The acrylamide content in tested 119 foods varied from 18 to 2175 µg/kg of product. The highest mean value of this substance was found out in the pre-cooked French fries (1125 µg/kg). Among the processed cereals products the highest mean acrylamide content was recorded in the salty sticks amounted 361 µg/kg. The lowest mean acrylamide level was found in wheat and rye bread (61 µg/kg).

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Genetic polymorphisms of the DNA repair gene MPG may be associated with susceptibility to rheumatoid arthritis

84%

Chen S. Y., Wan L., Huang C. M., Huang Y. C., Sheu J. J. C., Lin Y. J., Liu S. P., Lan Y. C., Lai C. H., Lin C. W., Tsai C. H., Tsai F. J.

Journal of Applied Genetics

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2010

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tom 51

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nr 4

Rheumatoid arthritis (RA) is a chronic autoimmune disease and can lead to deformities and severe disabilities, due to irreversible damage of tendons, joints, and bones. A previous study indicated that a DNA repair system was involved in the development of RA. In this study, we investigated the association of four N-methylpurine-DNA glycosylase (MPG) gene polymorphisms (rs3176364, rs710079, rs2858056, and rs2541632) with susceptibility to RA in 384 Taiwanese individuals (192 RA patients and 192 control subjects). Our data show a statistically significant difference in genotype frequency distributions at rs710079 and rs2858056 SNPs between RA patients and control groups (P = 0.040 and 0.029, respectively). Our data also indicated that individuals with the GG genotype at rs2858056 SNP may have a higher risk of developing RA. In addition, compared with the haplotype frequencies between case and control groups, individuals with the GCGC haplotype appeared to be at a greater risk of RA progression (P = 0.003, OR = 1.75; 95% CI = 1.20-1.55). Our results suggest that rs710079 and rs2858056 polymorphisms and the GCGC haplotype in the MPG gene are associated with the risk of RA progression, and thus may be used as molecular markers of RA if they are confirmed by further research.

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Matrix metalloproteinase-2 C-1306T promoter polymorphism and breast cancer risk in the Saudi population

84%

Saeed H. M., Alanazi M. S., Alshahrani O., Parine N. R., Alabdulkarim H. A., Shalaby M. A.

Acta Biochimica Polonica

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2013

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tom 60

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nr 3

Matrix metalloproteinase-2 (MMP-2) is an enzyme with proteolytic activity against matrix proteins, particularly basement membrane constituents. A single nucleotide polymorphism (SNP) at -1306, which disrupts a Sp1-type promoter site (CCACC box), displayed a strikingly lower promoter activity with the T allele. In the present study, we investigate whether this MMP-2 SNP is associated with susceptibility to breast cancer in the Saudi population. Ninety breast cancer patients and 92 age matched controls were included in this study. TaqMan Allele Discrimination assay and DNA sequencing techniques were used for genotyping. The results showed that, the frequency of MMP-2 CC wild genotype was lower in breast cancer patients when compared with healthy controls (0.65 versus 0.79). The homozygous CC (OR=2, χ2=5.36, p=0.02) and heterozygous CT (OR=1.98, χ2=4.1, p=0.04) showing significantly high risk of breast cancer in the investigated group. In conclusion our data suggest that the MMP-2 C-1306T polymorphism may be associated with increased breast cancer risk in the Saudi population.

13

Obstetric complications, age of parents and a risk for schizophrenia

84%

Karakula H., Pawezka J., Grzywa A., Urbanska A., Szajer K., Sekunda A., Spila B., Wysocka A.

Polish Journal of Environmental Studies

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2004

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tom 13

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nr Suppl.2, Part 1

Schizophrenia is an etiologically complex disorder arising from the interactions between and a range of factors acting at various stages in life. Despite the 70 year history in scientific literature describing the correlation between obstetric complications as a risk factor for schizophrenia it is still the subject of many research studies. A relatively new trend in research is to analyze the ages of the mother, father and the occurrence of this disease. The aim of this research, based on a review of literature, was to present the current level of knowledge relating to these topics while taking into account the factors for three groups of obstetric complications: I - complications during pregnancy (preeclampsia, bleeding, diabetes, rhesus incompatibility, hypertension with diuretic treatment); II - abnormal fetal development (low birth weight, congenital malformations, reduced head circumference); and III - complications during delivery (uterine atony, asphyxia, emergency Cesarean section).

14

POlish-Norwegian Study (PONS): research on chronic non-communicable diseases in European high risk countries – study design

84%

Zatonski W. A., Manczuk M.

Annals of Agricultural and Environmental Medicine

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2011

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tom 18

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nr 2

15

Perception of health, obesity risk and dietary habits in youth

84%

Calisir H., Gunes Z., Ozvurmaz S.

Health Problems of Civilization

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2019

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tom 13

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nr 1

Background. The aim of this study was to determine the relationship between eating behaviour, health perception and obesity risk awareness in adolescents. Material and methods. This cross-sectional study was completed with 579 adolescents. Stratified and simple random sampling methods were used in the selection of the high schools, classes and students. The data was collected through the information form, Dutch Eating Behaviour Questionnaire and Perception of Health Scale. Results. The mean score of health perception of the adolescents was 52.34±7.59. There was a positive relationship between total health perception score and emotional eating behaviour score of the adolescents (p=0.003). There was a negative relationship between total health perception score restricted eating behaviour (p=0.029), and external eating behaviour score (p<0.001). The emotional eating behaviour (p=0.007), external eating behaviour (p=0.001) and total eating behaviour score (p<0.001) of the adolescents who believed they had an obesity risk were found to be higher than the adolescents who believed they did not. Conclusions. The adolescents with better health perception are less affected by the environment and are able to restrict their food choices. The adolescents who think that they have an obesity risk consume more food due to their emotional state and external exposure.

16

Species composition and dynamics of mosquito occurrence in Eastern Slovakia in 2010-2014

84%

Bockova E., Kocisova A.

Annals of Parasitology

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2016

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tom 62

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nr Suppl.

17

Dietary gender differences in terms of the risk of atherogenesis in Poland

84%

Smidowicz A., Regula J.

Acta Scientiarum Polonorum. Technologia Alimentaria

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2015

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tom 14

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nr 3

Introduction. Diet plays an important role in prevention of atherosclerosis. The objective of the study was to assess differences in the dietary intake and nutritional status in women and men in terms of atherogenesis risk. Material and methods. The study involved 41 women and 49 men aged 40+. The nutrient intake was assessed using 7-day dietary records. The nutritional status was estimated on the basis of antropometric measurements and biochemical blood parameters. The differences between diets and the nutritional status depending on sex was evaluated by oneway analysis of variance. The dependencies between the nutritional status and the diet factors were assessed using multiple regression. Results and discussion. It was found that a significant proportion of the women and men were overweight or obese, had lipid disorders and impaired fasting glucose. Diets of women and men were poorly balanced. A significant correlation between the level of energy from protein, as well as the energy supply and the LDL cholesterol concetration was found in the women. A positive correlation between energy from protein as well as total energy in the diet and body weight, was observed in women and men. Moreover, protein intake was positively correlated with BMI and waist circumference among the men. In the men, the level of serum triglycerides correlated with an increase in dietary cholesterol and a decrease in energy value. Conclusion. This study indicates that an inadequate diet among both men and women represents a real health danger of developing atherosclerotic plaque.

18

ECG abnormalities and coronary risk factors in abdominal and gluteal-femoral obesity

84%

Bialkowska M.

Żywienie Człowieka i Metabolizm

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1990

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tom 17

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nr 4

Zaburzenia w zapisie Ekg charakterystyczne dla niedokrwiennej choroby serca były częstsze (15%) u pacjentów z otyłością typu brzusznego niż u osób z otyłością pośladkowo-udową (3%). Wykazano, że podwyższone ciśnienie skurczowe i rozkurczowe oraz poziom cholesterolu i trójglicerydów w surowicy są częstsze w otyłości brzusznej (AO) niż w otyłości pośladkowo-udowej (GO).

19

Association between polymorphisms in CHRNA3 and PHACTR2 gene and environment and NSCLC risk in Chinese population

84%

Lou G., Zhang Y., Bao W., Deng D.

Acta Biochimica Polonica

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2014

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tom 61

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nr 4

20

The risk of tick-borne diseases in Szczyrk (Province Silesian)

84%

Nikiel J., Asman M., Nowak-Chmura M.

Annals of Parasitology

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2016

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tom 62

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nr Suppl.

Ograniczanie wyników

The risk of overweight and obesity in chronic diseases among Warsaw inhabitants measured by self-reported method

Sperm epigenetic profile and risk of cancer

Coffee consumption vs. cancer risk - a review of scientific data