Wyniki wyszukiwania

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In vitro effects of polychlorinated biphenyls (PCBs) on the contractility of bovine myometrium from the periovulatory stage of the estrous cycle

100%

Wrobel M., Kaminski K., Kotwica J.

Reproductive Biology

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2005

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tom 05

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nr 3

2

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Effects of glutamate and zinc ions on the contractility of vascular smooth muscle preparations

84%

Nguyen-Duong H.

Journal of Elementology

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2010

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tom 15

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nr 3

559-572

It was shown in this study that isolated porcine coronary arteries (PCA) contracted by depolarization with high Ko or by histamine are dose-dependently relaxed by glutamic acid, aspartic acid, N-methyl-asparate (NMDA) and γ-aminobutyric acid (GABA). Zn2+ was also shown to relax dose-dependently PCA contractions induced by 50 mM KCl with an ED50 value of about 1.5 mM and to inhibit dose-dependently histamine-induced contractions, shifting ED50 values from 6μM to 40 μM, not affecting however corresponding cumulative concentration-response (CCR) curves established for acetylcholine-induced contractions. Furthermore, since Zn2+ ions are co-localized in many glutamatergic synapses of the central nervous system, it has been postulated in analogy to glutamate neurotoxicity that perturbations of the synaptic zinc concentrations might be a triggering factor in several cerebral diseases, such as ischemic strokes and sustained seizures. Unfortunately, little is known so far about effects of glutamate and zinc ions on the vascular tone. Although the nature of the glutamatergic receptors occurring in the blood vessels investigated in this study remains unclear, the results suggest that glutamate and Zn2+ ions interact with voltage-gated as well with ligand-operated Ca-channels. An interesting aspect might be the putative role of glutamate and zinc as long-term toxic agents in the early steps of the pathomechanisms leading to degenerative vascular lesions.

3

The influence of male pheromones on the contractile reactivity of the isolated superficial veins of the nose and face during the estrous cycle in gilts

84%

Grzegorzewski W. J.

Polish Journal of Veterinary Sciences

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2005

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tom 08

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nr 1

4

The role of perivascular adipose tissue and endogenous hydrogen sulfide in vasoactive responses of isolated mesenteric arteries in normotensive and spontaneously hypertensive rats

84%

Cacanyiova S., Majzunova M., Golas S., Berenyiova A.

Journal of Physiology and Pharmacology

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2019

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tom 70

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nr 2

5

The effect of resveratrol on contractility of non-pregnant rat uterus: the contribution of K+ channels

84%

Novakovic R., Ilic B., Beleslin-Cokic B., Radunovic N., Heinle H., Scepanovic R., Gojkovic-Bukarica L.

Journal of Physiology and Pharmacology

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2013

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tom 64

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nr 6

6

Beta-adrenergic antagonists influence abdominal aorta contractility by mechanisms not involving beta-adrenergic receptors

84%

Hauzer W., Bujok J., Czerski A., Rusiecka A., Pecka E., Gnus J., Zawadzki W., Witkiewicz W.

Folia Biologica

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2014

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tom 62

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nr 3

7

Electrical activity of canine gallbladder

84%

Konturek J. W., Scott G. W., Kingma Y. J.

Journal of Physiology and Pharmacology

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1991

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tom 42

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nr 1

Our aims were to describe the myoelectrical activity in the single very thin layer of muscle of the canine gallbladder. The study was performed on 22 freshly removed canine gallbladders. Electrical activity was studied by the single sucrose-gap method and contractility of the tissue was measured simultaneously using a force transducer. The strips (15x1 mm) from different regions of gallbladder (fundus, corpus, neck) were cut in longitudinal, circular and oblique axes. The sucrose-gap apparatus together with connecting tubes, solutions and electrodes were kept at 37°C and the initial tension applied to the tissue was set to 1 g. In 82.7% of recordings, spontaneous myoelectrical activity consisted of regular rhythmic changes in membrane potential similar to slow waves recorded in intestinal tissue. The overall mean frequency was 11.4 ± 5.2 (mean ±SD) cycles per min: 11.1 ± 4.4 cycles per min in fundus, 11.9 ± 6.2 cycles per min in corpus and 10.8 ± 3.8 cycles per min in the neck of the gallbladder. In 84.2% of cases electrical activity correlated with mechanical activity and preceded it. No significant differences were seen between the electrical patterns in strips with different orientations or from the different regions of the gallbladder.

8

In vitro study on the effects of some selected agonists and antagonists of alpha1-adrenergic receptors on the contractility of the aneurysmally-changed aortic smooth muscle in humans

67%

Gnus J., Czerski A., Ferenc S., Zawadzki W., Witkiewicz W., Hauzer W., Rusiecka A., Bujok J.

Journal of Physiology and Pharmacology

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2012

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tom 63

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nr 1

9

In vitro contractility of normal and aneurysmal abdominal aorta muscle coat sections in human and animal material

67%

Gnus J., Czerski A., Zawadzki W., Witkiewicz W., Hauzer W., Rusiecka A., Ferenc S.

Folia Biologica

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2012

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tom 60

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nr 1-2

10

Nonspecific effects of ligands on the beta-adrenergic receptors in rabbit abdominal aorta in vitro

67%

Gnus J., Czerski A., Bujok J., Ferenc S., Zawadzki W., Witkiewicz W., Hauzer W., Rusiecka A., Janeczek M.

Folia Biologica

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2013

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tom 61

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nr 3-4

11

Biochemical characteristics of myofibrillar proteins of the fish parasite Isoparorchis hypselobagri (Trematoda) as survival traits in an oxygen-rich environment

67%

Abbasi U., Ahmad R., Hasnain A.-U.

Biological Letters

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2012

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tom 49

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nr 1

Ograniczanie wyników

In vitro effects of polychlorinated biphenyls (PCBs) on the contractility of bovine myometrium from the periovulatory stage of the estrous cycle

Effects of glutamate and zinc ions on the contractility of vascular smooth muscle preparations

The influence of male pheromones on the contractile reactivity of the isolated superficial veins of the nose and face during the estrous cycle in gilts

The role of perivascular adipose tissue and endogenous hydrogen sulfide in vasoactive responses of isolated mesenteric arteries in normotensive and spontaneously hypertensive rats

The effect of resveratrol on contractility of non-pregnant rat uterus: the contribution of K+ channels

Beta-adrenergic antagonists influence abdominal aorta contractility by mechanisms not involving beta-adrenergic receptors

Electrical activity of canine gallbladder

In vitro study on the effects of some selected agonists and antagonists of alpha1-adrenergic receptors on the contractility of the aneurysmally-changed aortic smooth muscle in humans

In vitro contractility of normal and aneurysmal abdominal aorta muscle coat sections in human and animal material

Nonspecific effects of ligands on the beta-adrenergic receptors in rabbit abdominal aorta in vitro

Biochemical characteristics of myofibrillar proteins of the fish parasite Isoparorchis hypselobagri (Trematoda) as survival traits in an oxygen-rich environment