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Dynamics of morphological lesions in the course of contact dermatitis induced in mice by sodium lauryl sulphate

100%

Kapusniak V.

Bulletin of the Veterinary Institute in Puławy

2007

tom 51

nr 1

The present study is aimed at the determination of the character and intensity of morphological lesions in the skin, subjected to action of sodium lauryl sulphate as well as establishing, and if yes, to which extent the dermal process induced by primary chronic irritant, affects the reaction to secondary application of the damaging agent. The experiments were conducted on 24 white male mice of the inbred Balb/c strain. Surface of hairy skin (approximately 1 cm²), in the lumbo-dorsal region, was subjected to the action of sodium lauryl sulphate. The studies demonstrated differences in the intensity of the reaction not only among individual groups of experimental animals or individual animals within the group, but also between neighbouring sites in the skin of the same individual. Both the extent of thickening of epidermis and intensity of its keratinisation differed significantly between individual fields of the same section. In vicinity of necrotic regions, the areas were noted in which the epidermis underwent slight hypertrophy only or was almost unaltered, comparable to the control.

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Allergy to tetramethylthiuram disulphide, a component of pesticides and rubber

100%

Rudzki E., Rebandel P.

Annals of Agricultural and Environmental Medicine

1998

tom 05

nr 1

Zaburzenia strukturalne i czynnosciowe skory poddanej dzialaniu preparatu Domestos

59%

Kapusniak V., Houszka M.

Acta Scientiarum Polonorum. Medicina Veterinaria

2002

tom 01

nr 1

31-42

Ograniczanie wyników

1 Acta Scientiarum Polonorum. Medicina Veterinaria

1 Annals of Agricultural and Environmental Medicine

1 Bulletin of the Veterinary Institute in Puławy

2 Kapusniak V.

1 Houszka M.

1 Rebandel P.

1 Rudzki E.

1 2007

1 2002

1 1998

Wyniki wyszukiwania

Dynamics of morphological lesions in the course of contact dermatitis induced in mice by sodium lauryl sulphate

Allergy to tetramethylthiuram disulphide, a component of pesticides and rubber

Zaburzenia strukturalne i czynnosciowe skory poddanej dzialaniu preparatu Domestos