Wyniki wyszukiwania

Wyszukiwano:
w słowach kluczowych: conformational property

Sortuj według:

Ogranicz wyniki do:

Conformational properties of N-acetyl-L-alanine N',N'-dimethylamide

100%

Siodlak D., Rzeszotarska B., Broda M. A.

Acta Biochimica Polonica

2004

tom 51

nr 1

Ab initio/DFT analysis of the conformational properties of free Ac-Ala-NMe2 (N-acetyl-L-alanine-N,N-dimethylamide) in terms of the N-H-O, N-H-N, C-H-O hydrogen bonds and C = O - dipole attractions was performed. The Ala residue combined with the C-terminal tertiary amide prefers an extended conformation and that characteristic of the (i + 1)th position of the βVIb turn. These can be easily remodelled into a structure compatible with the (i + 1)th position of the ySlI/ySVIa turn. The residue has also the potential to adopt the conformation accommodated at both central positions of the βIII/βIIIr turn or the (i + 1)th position of the βI/β'I turn.

Conformational properties of N',N'-dimethylamides of N-acetyldehydroalanine and N-acetyl-[Z]-dehydrophenylalanine

84%

Siodlak D., Broda M. A., Rzeszotarska B., Koziol A. E., Dybala I.

Acta Biochimica Polonica

2001

tom 48

nr 4

Conformational preferences of Ac-ΔAla-NMe2 and Ac-(Z)-ΔPhe-NMe2 were studied and compared with those of their monomethyl counterparts as well as with those of their saturated analogues. X-Ray data and energy calculations revealed a highly conservative conformation of the dehydro dimethylamides, which is located in a high-energy region of the Ramachandran map.

Ograniczanie wyników

2 Acta Biochimica Polonica

2 Broda M. A.

2 Rzeszotarska B.

2 Siodlak D.

1 Dybala I.

1 Koziol A. E.

1 2004

1 2001

Wyniki wyszukiwania

Conformational properties of N-acetyl-L-alanine N',N'-dimethylamide

Conformational properties of N',N'-dimethylamides of N-acetyldehydroalanine and N-acetyl-[Z]-dehydrophenylalanine