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Clinical use and therapeutic potential of IVIG/SCIG, plasma-derived IgA or IgM, and other alternative immunoglobulin preparations

100%

Spath P. J., Schneider C., von Gunten S.

Archivum Immunologiae et Therapiae Experimentalis

2017

tom 65

nr 3

Association of oxidative stress and GST-T1 gene with childhood bronchial asthma

80%

Babusikova E., Jesenak M., Kirschnerova R., Banovcin P., Dobrota D.

Journal of Physiology and Pharmacology. Supplement

2009

tom 60

nr 5

Ulcerative colitis in AKR mice is attenuated by intraperitoneally administered anandamide

80%

Engel M. A., Kellermann C. A., Rau T., Burnat G., Hahn E. G., Konturek P. C.

Journal of Physiology and Pharmacology

2008

tom 59

nr 4

673-689

Anti-inflammatory and anti-nociceptive properties of endocannabinoids and synthetic cannabinoid compounds were described previously. We studied effects of the endogenous cannabinoid anandamide (N-arachidonylethanolamine) in experimental colitis induced by TNBS (2,4,6-trinitrobenzene sulfonic acid) in AKR mice. A scoring system was used to describe clinical and macroscopic changes. Intraperitoneally administered anandamide significantly reduced experimental colitis, quantified by macroscopical and histological scoring systems as well as pro-inflammatory cytokine mRNA expression. We conclude that systemically administered anandamide attenuates TNBS colitis in mice, and that systemically active cannabinoid compounds might have therapeutic potential for the treatment of IBD.

Ograniczanie wyników

1 Archivum Immunologiae et Therapiae Experimentalis

1 Journal of Physiology and Pharmacology

1 Journal of Physiology and Pharmacology. Supplement

1 Babusikova E.

1 Banovcin P.

1 Burnat G.

1 Dobrota D.

1 Engel M. A.

1 Hahn E. G.

1 Jesenak M.

1 Kellermann C. A.

1 Kirschnerova R.

1 Konturek P. C.

1 Rau T.

1 Schneider C.

1 Spath P. J.

1 von Gunten S.

1 2017

1 2009

1 2008

Wyniki wyszukiwania

Clinical use and therapeutic potential of IVIG/SCIG, plasma-derived IgA or IgM, and other alternative immunoglobulin preparations

Association of oxidative stress and GST-T1 gene with childhood bronchial asthma

Ulcerative colitis in AKR mice is attenuated by intraperitoneally administered anandamide