Wyniki wyszukiwania - AGRO

1

Expression of the histone H3 gene in the assessment of cellular proliferation activity in colitis ulcerosa

100%

Orchel J., Mazurek U., Stadnicki A., Wilczok T.

Folia Histochemica et Cytobiologica. Supplement

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2001

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tom 39

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nr 1

2

CK2: a protein kinase in need of control

88%

Boldyreff B., Guerra B., Issinger O. G., Pinna L. A.

Cellular and Molecular Biology Letters

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1998

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tom 03

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nr 3

3

Differentiation of neural stem cells derived from human cord blood (HUCB-NSC) under low oxygen conditions

75%

Podobinska M., Szablowska-Gadomska I., Winiarska H., Buzanska L.

Acta Neurobiologiae Experimentalis

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2013

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tom 73

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nr 1

In the human body, stem cells are located in niches, which are extremely complex microenvironments (with specified oxygen conditions and cellular together with extracellular matrix components arranged as a 3D structure). The influence of signals from niches seems to play an important role in maintenance of stem cells pluripotency and in their differentiation. We have been investigating the influence of the different niche components on the proliferation and differentiation of neural stem cells into specific cell types as well as the molecular mechanisms underlying this cell responses. In this study we are investigating the influence of low oxygen tension conditions on proliferation and differentiation of Human Umbilical Cord Blood of Neural Stem Cell (HUCB-NSC). Human Neural Stem Cells (NSC) in their physiological niches are exposed to 2–8% oxygen level. For that purpose, HUCB-NSC, were cultivated in two oxygen tension conditions: 21% and 5% with or without the presence of differentiation factor dBcAMP (N6,2′-O-Dibutyryladenosine 3′,5′-cyclic monophosphate sodium salt). We compared the expression of the markers characteristic for proliferation (Ki67) as well as neuronal and astroglial lineage commitment (MAP2, GFAP, β-tubulin, NF200). The presence of tested markers was revealed on the protein (immunocytochemistry) and gene expression level (Real-Time PCR). Our data show, that the low oxygen tension promote HUCB-NSC differentation into neuronal lineage. We also observed that low concentration of oxygen increases cell proliferation.Sponsored by grant from Polish Ministry of Scientific Research and Higher Education No 5978/B/PO1/2010/38

4

Targeting clusterin in prostate cancer

75%

Rizzi F., Bettuzzi S.

Journal of Physiology and Pharmacology. Supplement

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2008

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tom 59

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nr 9

265-274

5

Insulin-like growth factor 1

75%

Gronek P., Rychlewski T., Slomski R., Stankiewicz K., Lehmann J.

Studies in Physical Culture and Tourism

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2005

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tom 12

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nr 1

6

Effect of extremely low frequency electromagnetic fields on cell proliferation, antioxidative enzyme activities and lipid peroxidation in 3T3-L1 preadipocytes - an in vitro study

75%

Zwirska-Korczala K., Jochem J., Adamczyk-Sowa M., Sowa P., Polaniak R., Birkner E., Latocha M., Pilc K., Suchanek R.

Journal of Physiology and Pharmacology. Supplement

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2005

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tom 56

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nr 6

101-108

The exposure to extremely low frequency electromagnetic field (ELF-MF, frequencies less than 200-300 Hz) can alter the transcription and translation of genes, influence the cell proliferation rate and affect enzyme activities. Moreover, the hypothesis that ELF-MF increases free oxygen metabolites generation has been proposed. Since recent in vivo studies suggest that electric and magnetic fields are able to affect adipose cells metabolism. The aim of the study was to examine the effects of ELF-MF (frequency of basic impulse 180-195 Hz, induction 120 µT) on cell proliferation, antioxidative enzyme activities and malondialdehyde (MDA) concentration in 3T3-L1 preadipocyte cell culture. We found that ELF-MF application lasting 36 minutes daily failed to influence cell count after 24h and 48 h of incubation. After 24 h, in the ELF-MF treated group, manganese- and copper-zinc-containing superoxide dismutase (MnSOD and Cu/ZnSOD) isoenzymes media activities were decreased, catalase activity was increased, whereas there were no significant differences in glutathione peroxidase (GSH-Px) and glutathione reductase (GSSG-Rd) activities in comparison to the control. After 48 h of incubation, all enzyme activities were reduced, except for GSSG-Rd, in which no changes were noticed. MDA concentration at 24 h after incubation with the exposure to ELF-MF was significantly higher in comparison to the control, without ELF-MF. After 48 h of incubation, MDA levels were significantly lower in both groups with no differences between the groups without and with ELF-MF. We conclude that ELF-MF influences antioxidative enzyme activities and increases lipid peroxidation in 3T3-L1 preadipocyte cultures.

7

Effect of chemical sympathectomy on bone marrow cell proliferation in the rat

75%

Tabarowski Z.

Acta Biologica Cracoviensia. Series Zoologia

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2008

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tom 50

11-16

8

Expression level of TRPM7 channel in mammary epithelial cells selected to grow in very low [0.025 mM] and very high [45 mM] magnesium containing media

75%

Simonacci M., Trapani V., Boninsegna A., Cittadini A., Wolf F. I.

Journal of Elementology

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2005

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tom 10

|

nr 4 Suppl.1

97-98

9

Encephalitozoon intestinalis infection impacts the expression of apoptosis-related genes in U937 macrophage cells

75%

Cetinkaya U., Caner A., Charyyeva A., Senturk M., Eren M.

Acta Parasitologica

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2021

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tom 66

|

nr 2

10

Preliminary results on exogenous ghrelin administration via stomach tube influence on the crypt cell proliferation in the small intestine mucosa of neonatal piglets

75%

Slupecka M., Wolinski J.

Journal of Animal and Feed Sciences

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2007

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tom 16

|

nr 3

445-451

11

The inhibition of cell proliferation by Helicobacter pylori products

75%

Rudnicka W., Chmiela M., Covacci A., Wadstrom T.

Journal of Physiology and Pharmacology. Supplement

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1997

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tom 48

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nr 1

12

A novel polypeptide from Cervus nippon Temminck proliferation of epidermal cells and NIH3T3 cell line

75%

Guan S. W., Duan L. X., Li Y. Y., Wang B. X., Zhou Q. L.

Acta Biochimica Polonica

|

2006

|

tom 53

|

nr 2

A novel polypeptide, velvet antler polypeptide (VAPPs), having a stimulary effect on proliferation of some cell was isolated from the velvet antler of sika deer (Cervus nippon Temminck). This polypeptide consists of a single chain of 32 amino-acid residues VLSAT DKTNV LAAWG KVGGN APAFG AEALE RM. VAPPs showed marked stimulary effect on rat epidermal cells and NIH3T3 cell line (dose range from 10-40 mg·L-1 and 5-80 mg·L-1, respectively).

13

Angiotensins II and IV modulate adrenocortical cell proliferation in ovariectomized rats

75%

Siejka A., Melen-Mucha G., Mucha S. A., Pawlikowski M.

Journal of Physiology and Pharmacology

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2006

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tom 57

|

nr 3

Effects of angiotensins II (AngII), angiotensin IV (AngIV, 3-8 fragment of angiotensin II) and losartan (an antagonist of angiotensin receptor type 1) on the proliferation of adrenocortical cells in ovariectomized rats have been studied. The incorporation of bromodeoxyuridine (BrdU) into cell nuclei was used as an index of cell proliferation. AngIV decreased BrdU labeling index mainly in the reticularis zone and losartan (Los) was able to partially reverse this inhibitory effect of AngIV. AngII had no effect on the adrenocortical cell proliferation when given alone, however Los given simultaneously diminished BrdU incorporation into nuclei of glomerulosa and reticularis zones as compared with AngII. These findings suggest that AngII and AngIV modulate adrenocortical cell proliferation in ovariectomized rats.

14

Cytotoxicity and cell death: apoptosis or necrosis or both?

75%

Cervinka M., Cervinkova Z., Puza V.

Folia Histochemica et Cytobiologica. Supplement

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1997

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tom 35

|

nr 2

15

An evaluation of Ki-67 and PCNA expression in conjunctival and eyelid tumours

75%

Reszec J., Kanczuga-Koda L., Sulkowska M., Koda M., Cylwik J., Barwijuk-Machala M., Sulkowski S.

Folia Morphologica

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2004

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tom 63

|

nr 1

The aim of our study was an evaluation of the expression of cell proliferation markers (PCNA and Ki-67) in conjunctival and eyelid papillomas and squamous and basal cell cancers. A series of 9 cases of squamous cell cancer (SCC), 15 cases of basal cell cancer (BCC) and 43 cases of squamous cell papilloma (SCP) were assessed using the immunohistochemical method with monoclonal antibodies. PCNA overexpression was observed in 100% of SCP, in 88.8% of SCC and in 100% of BCC cases. Ki-67 overexpression was seen in 32.5% of cases of SCP, in 22.2% of SCC and in 66.6% of BCC. The results showed that an evaluation of Ki-67 expression is the most valuable cell proliferation marker.

16

MicroRNAs: potential biomarkers and targets of therapy in allergic diseases?

63%

Specjalski K., Jassem E.

Archivum Immunologiae et Therapiae Experimentalis

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2019

|

tom 67

|

nr 4

17

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Glutathione-dependent regulation of cell proliferation and root meristem development

63%

Schnaubelt D., Queval G., Dong Y., Diaz-Vivancos P., Hannah M., Foyer C.

BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology

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2013

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tom 94

|

nr 2

18

Overexpression of human CUTA isoform2 enhances the cytotoxicity of copper to HeLa cells

63%

Yang J., Li Q., Yang H., Yan L., Yang L., Yu L.

Acta Biochimica Polonica

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2008

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tom 55

|

nr 2

411-415

Copper, an essential transient element, can be toxic to cells when present in excess. Altered copper homeostasis is involved in pathological events of many diseases. Human CUTA isoform2 is a member of cation tolerance protein (CutA1) family. In this study, we examined the effect of CUTA isoform2 overexpression on copper toxicity. It was shown that overexpressed CUTA isoform2 sensitized HeLa cells to copper toxicity by promoting copper-induced apoptosis. The inhibition effect of excessive copper on cell proliferation was also enhanced by overexpressed CUTA isoform2. So CUTA isoform2 was implicated to be involved in the cytotoxicity of copper.

19

Evaluation of endothelial function by flow-mediated dilation: a comprehensive review in rheumatic disease

63%

Moroni L., Selmi C., Angelini C., Meroni P. L.

Archivum Immunologiae et Therapiae Experimentalis

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2017

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tom 65

|

nr 6

20

The effect of dental gel formulation on human primary fibroblasts - an in vitro study

63%

Sterczala B., Kulbacka J., Saczko J., Dominiak M.

Folia Histochemica et Cytobiologica

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2020

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tom 58

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nr 2

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