Wyniki wyszukiwania - AGRO

1

Potassium channel openers and the expression of BCL-type proteins in cardiac myocytes

100%

Kicinska A., Szewczyk A.

Cellular and Molecular Biology Letters

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2002

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tom 07

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nr Suppl.

2

Importance of basic mechanisms of magnesium in cardiovascular therapy

88%

Kiss Z.

Journal of Elementology

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2005

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tom 10

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nr 4 Suppl.1

40-41

3

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The level of knowledge of students of the Medical University about cardiovascular disease prevention

88%

Krzyzanowska E., Nowak K., Baczewska B., Kropornicka B., Wawryniuk A., Drop B., Daniluk J.

Health Problems of Civilization

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2014

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tom 08

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nr 4

The most effective and the cheapest method of cardiovascular disease prevention is changing lifestyle. Cardiovascular disease is caused by many factors. They include: a diet rich in saturated fat and cholesterol, smoking, a sedentary lifestyle, physical inactivity, overweight and obesity. The aim of the research was to assess the level of knowledge of the students of the Medical University about cardiovascular disease prevention. Material and methods: Research was conducted on 200 students of the Medical University of Lublin, residing in the Student House No. 4 in Lublin. Self-authorship questionnaires were used to assess the level of knowledge of the students of the Medical University about cardiovascular disease prevention. Research results: The students of the Medical University have broad knowledge about the influence of physical activity, diet, cigarettes and alcohol use on cardiovascular disease prevention. 90.5 percent of the respondents know that smoking greatly increases the risk of cardiovascular disease. More than a half of the students are aware that excessive alcohol consumption has a negative impact on the cardiovascular system. 38.67 percent of the respondents recognize moderate alcohol consumption as protective for cardiovascular disease. The remaining 3.13 percent of the students have no knowledge about this issue. Almost half of the respondents (45 percent) is aware that psychosocial factors have an impact on the cardiovascular system. 86.5 percent of the students believe that there is a correlation between cardiovascular disease and factors such as: low socioeconomic status, social isolation, stress, negative emotions, depression. The remaining 13.5 percent of the respondents have incomplete knowledge about this issue. Almost the half of the respondents knows that type A personality increases the risk of cardiovascular disease, whereas the remaining 52 percent of the students have incomplete knowledge about this issue.

4

Molecular biomedicine and the unraveling of complex phenotypes

88%

Pignatti P. F.

Journal of Applied Genetics

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2004

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tom 45

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nr 4

5

Plasma homocysteine level and the course of ischemic stroke

88%

Pniewski J., Chodakowska-Zebrowska M., Wozniak R., Stepien K., Stafiej A.

Acta Neurobiologiae Experimentalis

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2003

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tom 63

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nr 2

6

Effect of fructooligosaccharides in Cynara scolymus and Allium cepa on carbohydrate and lipid metabolism in rats

75%

Moharib S. A., Shehata M. M., Salama A. F., Hegazi M. A.

Electronic Journal of Polish Agricultural Universities. Series Veterinary Medicine

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2014

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tom 17

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nr 1

7

A cross-sectional study of cardiovascular disease and associated factors

75%

Islami F., Manczuk M., Vedanthan R., Vatten L., Polewczyk A., Fuster V., Boffetta P., Zatonski W. A.

Annals of Agricultural and Environmental Medicine

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2011

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tom 18

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nr 2

8

Acceptance of illness and satisfaction with life among patients with arterial hypertension

75%

Baczewska B., Kropornicka B., Sepiolo J., Krzyzanowska E., Olszak C., Szymczuk E., Daniluk J.

Health Problems of Civilization

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2015

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tom 09

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nr 3

The aim of this study was to determine and compare the degree of acceptance of the disease and the level of satisfaction with life among people with diagnosed hypertension. The research was carried out by means of a diagnostic survey. The study used the scale of AIS - Approval Illness Scale (Acceptance of Illness Scale). For measuring life satisfaction ladder Cantrill was used. It assessed satisfaction with life on a scale from 0 to 10. The study was conducted in June 2014 among the residents of Lubelskie and Świętokrzyskie voivodships. The study was anonymous. The approval of the Bioethics Committee at the Medical University of Lublin (KE-0254/176/2014) was received for carrying out the tests. The study included patients diagnosed with hypertension – total of 154 people. The study has shown the average degree of acceptance of the disease. Illness and healing therapy did not impact negatively the functioning of most respondents. The respondents described their adaptation to the limitations imposed by the disease in different degrees. The vast majority of respondents did not have any problems arising from the disease and did not abandon their favorite activities. Every third respondent with hypertension felt as being a defective person and dependent on other people. The relation between satisfaction with their own lives, and the level of acceptance of the disease was concluded in that study. The higher the degree of satisfaction with patients’ lives, the higher the acceptance of illness. Studies have shown positive correlations between gender, age, place of residence, duration of illness and education, and acceptance of the disease. In contrast, there was no statistically significant association between marital status and the test subject.

9

The role of microRNA (miRNA) as a biomarker in HPV and EBV-related cancers

75%

Kolesnik M., Stepien E., Polz-Dacewicz M.

Journal of Pre-Clinical and Clinical Research

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2021

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tom 15

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nr 2

10

Vascular related pathologies in cardiovascular disease and cancer

75%

Ananthaseshan S., Religa P.

Health Problems of Civilization

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2018

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tom 12

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nr 3

Cancer and Cardiovascular diseases (CVD) are the two most prominent causes of death worldwide. Emerging evidence indicates shared risk factors and a common biology between these diseases. For instance, chronic inflammation has a significant role in contributing to both diseases. An alteration of the vasculature and the endothelial cells plays a key role in pathogenesis of CVD and cancer. The widespread overlap regarding disease prevention and risk factors for these diseases suggest a common mechanism in terms of molecular pathways. The goal of this tutorial is to present common problems and mechanism of these two mayor diseases.

11

Molecular mechanisms of magnesium in atherosclerosis

75%

Bernardini D., Mazur A., Maier J.

Journal of Elementology

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2005

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tom 10

|

nr 4 Suppl.1

17

12

Case of the PONS study

75%

Yusuf S.

Annals of Agricultural and Environmental Medicine

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2011

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tom 18

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nr 2

13

Adherence to nutrition guidelines in patients with cardiovascular diseases as a secondary prevention

75%

Wozniak A., Krotki M., Anyzewska A., Gornicka M., Wawrzyniak A.

Roczniki Państwowego Zakładu Higieny

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2017

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tom 68

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nr 4

Background. The appropriate nutrition is an important component of the secondary prevention of cardiovascular diseases (CVD). Objectives. The aim of the study was to investigate if the patients with cardiovascular disease were informed of the role of appropriate nutrition in prevention or received nutrition guidelines and to assess the dietary intake compared to recommendations for patients with cardiovascular disease who received or not nutrition guidelines. Material and Methods. The study was conducted among patients with cardiovascular disease (n = 127) of cardiological hospital clinic, aged 62 ± 11. The questionnaire was used to obtain personal and anthropometric details, information if patients had received nutrition guidelines. The method of 3-day food records was used for dietary assessment. Results. 20% of subjects had not received nutrition guidelines and almost 40% of subjects did not recognize the nutrition effect on cardiovascular disease development. Compared to the diets of the subjects who had not received nutrition guidelines, the diets of those who had received them were of significantly lower intake of: energy from saturated fatty acids (15%, p = 0.006), cholesterol (21%, p = 0.012) and higher intake (14-26%) of potassium (p = 0,003), sodium (p = 0.013), phosphorus (p = 0.044), magnesium (p = 0.003), iron (p = 0.005), copper (p = 0.001), zinc (p = 0.046). Among the patients who had received nutrition guidelines, percentage of the subjects whose intake of nutrients was consistent with recommendations was higher. Conclusions. Not all subjects had received nutrition guidelines. Diets of those who had received them were more balanced, but in neither group nutrition guidelines were complied with.

14

Cardiovascular effects of methacholine-induced airway obstruction in man

75%

Sharman J. E., Johns D. P., Marrone J., Walls J., Wood-Baker R., Walters E. H.

Journal of Physiology and Pharmacology

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2014

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tom 65

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nr 3

15

Prevalence of hypertension in a sample of Polish population - baseline assessment from the prospective cohort ‘PONS’ study

75%

Szuba A., Martynowicz H., Zatonska K., Ilow R., Regulska-Ilow B., Rozanska D., Wolyniec M., Einhorn J., Vatten L., Asvold B. O., Manczuk M., Zatonski W. A.

Annals of Agricultural and Environmental Medicine

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2011

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tom 18

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nr 2

16

Suppressor of cytokine signaling and accelerated atherosclerosis in kidney disease

75%

Wesoly J., Sikorski K., Lee C.-K., Bluyssen A. R.

Acta Biochimica Polonica

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2010

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tom 57

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nr 3

The prevalence of cardiovascular disease in patients with renal failure is extremely high and accounts for a large part of the morbidity and mortality. Inflammation participates importantly in host defense against infectious agents and injury, but also contributes to the pathophysiology of many diseases, including cardiovascular atherosclerosis, which is a main problem in patients with renal failure. Recruitment of blood leukocytes to the injured vascular endothelium characterizes the initiation and progression of atherosclerosis and involves many inflammatory mediators, modulated by cells of both innate and adaptive immunity. Excessive inflammatory and immune responses, communicated by these different cell types, are driven by inflammatory cytokines that promote associated tissue damage if cytokine signaling pathways remain unregulated. Thus, pathways capable of suppressing proinflammatory cytokine signaling hold the potential to limit life-threatening cardiovascular events caused by atherogenesis. Suppressor of cytokine signaling (SOCS) are a family of intracellular proteins, several of which have emerged as key physiological regulators of cytokine-mediated homeostasis, including innate and adaptive immunity. Accumulating evidence supports the idea that dysregulation of cytokine signaling by differential SOCS expression is involved in the pathogenesis of various inflammatory, and immunological diseases, including atherosclerosis. Based on recent observations, in which SOCS expression levels are profoundly altered in kidney disease, we discuss the possibilities of SOCS as new intracellular markers of inflammation as well as their potential atherogenic properties in renal failure related cardiovascular disease.

17

Effect of physical activity on IGF-1 and IGFBP levels in the context of civilization diseases prevention

75%

Majorczyk M., Smolag D.

Roczniki Państwowego Zakładu Higieny

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2016

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tom 67

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nr 2

Background. Insulin-like growth factor 1 (IGF-1) is known as somatomedin C. This polypeptide hormone is functionally and structurally similar to insulin. IGF-1 effects on tissue by the IGF-1R and the insulin-like growth factor-binding protein also known as IGFBP. Abnormal IGF-1 and IGFBP signaling are positively correlated with a high risk of selected civilization diseases development. Physical inactivity is a one of the main causes of majority of chronic diseases and it is associated with eg. IGF-1 and IGFBPs level. Objective. The aim of the study was to explanation the effect of physical activity on IGF-1 and its binding protein – IGFBPs concentration in the context of selected civilization diseases prevention. The review of clinical trial. Material and Methods. The review of articles had published in databases: MEDLINE, EMBASE, Scopus and Web of Science until December 2015. The selected prospective studies about the effect of exercise on IGF-1 level and its binding protein IGFBP in the context of selected civilization diseases prevention were collected. Results. The majority of the included studies indicate that mechanical loading is a key mechanism linking IGF-1/IGFBPs concentration and selected chronic diseases development. The duration and intensity of physical activity have a significant impact on IGF-1 and IGFBP serum. The highest concentration of IGF-1 in serum was after eccentric training. “Overtraining” increases unfavorable and unbound IGF-1 levels and contributes to the increased incidence of hormone-cancer and osteoarthritis. Conclusions. Irregularity of the GH/IGF-1 axis may affect on the development of rheumatic diseases, cardiovascular diseases (regulate cardiac growth and metabolism) and metabolic syndrome.

18

Regulation of human aldoketoreductase 1C3 [AKR1C3] gene expression in the adipose tissue

75%

Svensson P. A., Gabrielsson B. G., Jernas M., Gummesson A., Sjoholm K.

Cellular and Molecular Biology Letters

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2008

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tom 13

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nr 4

599-613

Aldoketoreductase 1C3 (AKR1C3) is a functional prostaglandin F synthase and a negative modulator of the availability of ligands for the nuclear receptor peroxisome proliferator-activated receptor-gamma (PPARγ). AKR1C3 expression is known to be associated with adiposity, one of the components of the metabolic syndrome. The aim of this study was to characterize the expression of AKR1C3 in the adipose tissue and adipocytes and to investigate its potential role in the metabolic syndrome. Using microarray analysis and realtime PCR, we studied the expression of AKR1C3 in adipose tissue samples from obese subjects with or without metabolic complications, during very low calorie diet-induced weight loss, and its expression in isolated human adipocytes of different sizes. The adipose tissue AKR1C3 expression levels were marginally lower in obese subjects with the metabolic syndrome compared with the levels in healthy obese subjects when analyzed using microarray (p = 0.078) and realtime PCR (p < 0.05), suggesting a secondary or compensatory effect. The adipose tissue mRNA levels of AKR1C3 were reduced during and after dietinduced weight-loss compared to the levels before the start of the diet (p < 0.001 at all time-points). The gene expression of AKR1C3 correlated with both adipose tissue mRNA levels and serum levels of leptin before the start of the diet (p < 0.05 and p < 0.01, respectively). Furthermore, large adipocytes displayed a higher expression of AKR1C3 than small adipocytes (1.5-fold, p < 0.01). In conclusion, adipose tissue AKR1C3 expression may be affected by metabolic disease, and its levels are significantly reduced in response to dietinduced weight loss and correlate with leptin levels.

19

Antisense oligonucleotides to PAI-1 mRNA as potential agents for therapeutic intervention in cardiovascular diseases

75%

Cierniewski C. S., Pawlowska Z., Pluskota E., Stasiak M., Kobylanska A., Misiura K., Maciaszek A., Koziolkiewicz M., Stec W. J.

Biotechnologia

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1996

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nr 4

20

From accuracy in protein synthesis to cardiovascular disease: The role of homocysteine

75%

Jakubowski H.

Biotechnologia

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2002

|

nr 3

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