Wyniki wyszukiwania

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Effects of whole-body electromyostimulation exercise and caloric restriction on cardiometabolic risk profile and muscle strength in obese women with the metabolic syndrome: a pilot study

100%

Reljic D., Konturek P. C., Herrmann H. J., Neurath M. F., Zopf Y.

Journal of Physiology and Pharmacology

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2020

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tom 71

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nr 1

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Weight loss-dependent and -independent effects of moderate calorie restriction on endothelial cell markers in obesity

100%

Korybalska K., Luczak J., Swora-Cwynar E., Kanikowska A., Czepulis N., Kanikowska D., Skalisz H., Breborowicz A., Grzymislawski M., Witowski J.

Journal of Physiology and Pharmacology

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2017

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tom 68

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nr 4

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Tissue-specific effect of refeeding after short- and long-term caloric restriction on malic enzyme gene expression in rat tissues

100%

Stelmanska E., Korczynska J., Swierczynski J.

Acta Biochimica Polonica

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2004

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tom 51

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nr 3

Restricting food intake to a level below that consumed voluntarily (85%, 70% and 50% of the ad libitum energy intake for 3 or 30 days) and re-feeding ad libitum for 48 h results in an increase of malic enzyme (ME) gene expression in rat white adipose tissue. The increase of ME gene expression was much more pronounced in rats maintained on restricted diet for 30 days than for 3 days. The changes in ME gene expression resembled the changes in the content of SREBP-1 in white adipose tissue. A similar increase of serum insulin concentration was observed in all groups at different degrees of caloric restriction and refed ad libitum for 48 h. Caloric restriction and refeeding caused on increase of ME activity also in brown adipose tissue (BAT) and liver. However, in liver a significant increase of ME activity was found only in rats maintained on the restricted diet for 30 days. No significant changes after caloric restriction and refeeding were found in heart, skeletal muscle, kidney cortex, and brain. These data indicate that the increase of ME gene expression after caloric re- striction/refeeding occurs only in lipogenic tissues. Thus, one can conclude that caloric restriction/refeeding increases the enzymatic capacity for fatty acid biosynthesis.

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Effect of caloric restriction on liver function in young and old ApoE/LDLr-/- mice

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Kostogrys R. B., Franczyk-Zarow M., Manterys A., Wybranska I.

Roczniki Państwowego Zakładu Higieny

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2018

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tom 69

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nr 1

Background. Caloric restriction (CR) leads to decrease metabolic intensity, which results in a reduction of oxygen consumption and the amount of free radicals. This can affect the function of the liver. Studies show that caloric restriction does not alter or significantly increase the enzyme activity associated with gluconeogenesis, but the effect was different according to the age of the model animals. Objective. The aim of the study was to determine the effect of caloric restriction on liver function in young and old ApoE/ LDLr-/- mice. Material and methods. Dietary experiments were performed on 2 and 5 month old male ApoE/LDLr-/- mice. Animals were divided into 3 experimental groups (n=6) and fed AIN’93G diet for 8 and 5 weeks, respectively. Control animals were fed ad libitum (AL) and housed in a colony cages. These animals were checked for dietary intake. The second group were also fed ad libitum but the animals were kept individually in cages (stress AL- sAL). Similarly to sAL group, the animals from the CR group were kept individually but received a 30% less diet compared to AL group. At the end of the experiment animals were euthanized and the blood, liver and adipose tissue have been collected. Alanine aminotransferase (ALT) as well as aspartate aminotransferase (AST) were measured in plasma. Fatty acid profile was evaluated (relative %) in adipose tissue (GC-MS). Liver’s stetosis was assessed. Results were analyzed statistically (ANOVA, STATISTICA v.10.0). Results. CR ApoE/LDLr-/- mice showed significantly lower body weight compared to animals, both AL and sAL. There were no significant differences between ALT and AST in both younger and older animals. However, negative tendencies were more pronounced in younger animals. In young animals CR significantly increased liver weight compared to AL (4.14 vs 3.73g/100g). In adipose tissue fatty acid profile differed in CR mice compared to control in young animals. Conclusions. Caloric restriction did not affect liver enzymes in mice. Caloric restriction showed similar but not identical metabolic activity in young and old mice.

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Circadian variations of serum thyrotropin, thyroxine, triiodothyronine, reverse triiodothyronine, corticosterone and lipids in starved rats

61%

Zwirska-Korczala K., Ostrowska Z., Kucharzewski M., Marek B., Kos-Kudla B., Buntner B., Swietochowska E.

Bulletin of the Polish Academy of Sciences. Biological Sciences

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1993

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tom 41

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nr 4

Ograniczanie wyników

Effects of whole-body electromyostimulation exercise and caloric restriction on cardiometabolic risk profile and muscle strength in obese women with the metabolic syndrome: a pilot study

Weight loss-dependent and -independent effects of moderate calorie restriction on endothelial cell markers in obesity

Tissue-specific effect of refeeding after short- and long-term caloric restriction on malic enzyme gene expression in rat tissues

Effect of caloric restriction on liver function in young and old ApoE/LDLr-/- mice

Circadian variations of serum thyrotropin, thyroxine, triiodothyronine, reverse triiodothyronine, corticosterone and lipids in starved rats