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Ocular cysticercosis with intermittent blindness

100%

Sharma R., Dey A. K., Joshi K., Thakkar H.

Annals of Parasitology

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2015

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tom 61

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nr 4

We report this peculiar case of ocular cysticercosis with intermittent blindness which is never reported to our knowledge. This case highlights use of Ultrasound for examination of the posterior segment of eye globe. In limited facilities Ultrasound is the main modality to reach the diagnosis. We also wish to enforce the point that in endemic regions and in young population primary cysticercosis and its complications must be kept in differentials of cystic mass or calcified mass, as in this case, we have seen both the stages of cysticercosis progression.

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The nematodes Thelazia gulosa Railiet and Henry, 1910 and Thelazia skrjabini Erschov, 1928 as a cause of blindness in European bison (Bison bonasus) in Poland

84%

Demiaszkiewicz A. W., Moskwa B., Gralak A., Laskowski Z., Myczka A. W., Kolodziej-Sobocinska M., Kaczor S., Plis-Kuprianowicz E., Krzysiak M., Filip-Hutsch K.

Acta Parasitologica

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2020

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tom 65

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nr 4

3

Use of melatonin in circadian rhythm disorders and following phase shifts

84%

Skene D. J., Deacon S., Arendt J.

Acta Neurobiologiae Experimentalis

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1996

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tom 56

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nr 1

4

The role of the innate and adaptive immune responses in Acanthamoeba keratitis

84%

Niederkorn J. Y.

Archivum Immunologiae et Therapiae Experimentalis

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2002

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tom 50

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nr 1

5

In vitro angiomodulatory activity of sera from type 2 diabetic patients with background retinopathy

67%

Chorostowska-Wynimko J., Skopinski P., Szaflik J., Partyka I., Duda-Krol B., Anuszewska E., Skopinska-Rozewska E.

Journal of Physiology and Pharmacology. Supplement

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2005

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tom 56

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nr 4

65-70

Diabetic retinopathy is the leading cause of adult vision loss and blindness. The most important contributors to the development of diabetic retinopathy are hyperglycemia and hypoxemia that lead to increased vasopermeability, endothelial cell proliferation, and pathological neovascularization. In our previous studies, close relationship between proangiogenic activity of sera from type 2 diabetes mellitus patients (DM2) with background retinopathy, assessed in the in vivo serum-induced mouse cutaneous test (SIA), and VEGF and IL-18 serum concentration were observed. Moreover, it was clearly shown that IGF-1 might play an important role in the negative regulation of neoangiogenesis induced by DM2 patients' sera by diminishing the VEGF stimulatory effect. To confirm the observed phenomenon we evaluated the effect of DM2 patients' sera on the in vitro proliferative activity of human endothelial cells, which is critical for the sprouting and generation of new blood capillaries. Endothelial proliferative activity was significantly higher in the presence of sera from DM2 patients than from healthy controls (P<0.001), as estimated by the MTT test. Moreover, the examined sera from DM2 patients were characterized by increased IL-18 (P<0.05), diminished IGF-1 (P<0.02), and unchanged VEGF levels compared with those in controls. In conclusion, the present study showed a strong stimulatory effect of DM2 patients' sera on the proliferation of endothelial cells, which, along with the findings of our previous studies, proves that the described phenomenon is universal and valid for both animal and human endothelium.

Ograniczanie wyników

Ocular cysticercosis with intermittent blindness

The nematodes Thelazia gulosa Railiet and Henry, 1910 and Thelazia skrjabini Erschov, 1928 as a cause of blindness in European bison (Bison bonasus) in Poland

Use of melatonin in circadian rhythm disorders and following phase shifts

The role of the innate and adaptive immune responses in Acanthamoeba keratitis

In vitro angiomodulatory activity of sera from type 2 diabetic patients with background retinopathy