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A short history of insecticides

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This review contains a brief history of the use of insecticides. The peculiarities, main advantages, and disadvantages of some modern insecticides are described. The names of the discoverers of some of the most popular insecticide preparations on the world market, are listed. The tendencies to find new insecticides to control the quantity of phytophagous insects are discussed. Special attention is paid to the perspective of creating preparations based on nucleic acids, in particular DNA insecticides. The use of insect-specific, short single-stranded DNA fragments as DNA insecticides, is paving the way in the field of “intellectual” insecticides that “think” before they act. It is worth noting, though, that in the near future, the quantity of produced insecticides will increase due to the challenges associated with food production for a rapidly growing population. It is concluded, that an agreeable interaction of scientists and manufacturers of insecticides should lead to the selection of the most optimal solutions for insect pest control, which would be safe, affordable, and effective at the same time.
The year 1899 can be regarded as the beginning of the production of medications for animals in the Polish territories, for it was then that biological preparations made at the Department of Hygiene of the Jagiellonian University in Kraków were first mentioned by the press. The interwar period saw the development of not only the veterinary and bioveterinary industry, but also legislation that regulated its functioning. Although very advanced for those times, those laws were also susceptible to different interpretations and could easily be circumvented. In 1939, there were 33 Polish companies producing synthetic preparations and 6 producing serums and vaccines. One serious problem of the Polish pharmaceutical industry was the deficiency of domestic investment capital. The foreign ownership of the pharmaceutical industry amounted to 30%. Polish serums and vaccines for humans and animals fully covered the country’s needs and represented the strongest branch of the domestic pharmaceutical industry (in 1939, the Polish production of medicines met 3/4 of domestic demand). The development of industrial pharmacy in Poland was stopped by the outbreak of the Second World War. Many buildings were destroyed already at the beginning of the war in 1939. Post-war years showed that the foundations of the Polish pharmaceutical industry (including its veterinary branch) were solid. Polish pharmaceutical companies mostly recovered and sometimes even expanded their productive potential after the war.
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