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The influence of acute progressive hypoxia on bioelectrical activity of the brain

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Hypoxia, a noxious and hyperventilatory stimulus and a modifier of neuronal metabolism, could influence cortical function. In this study we attempted to assess any such influence, its determinants, and particularly the role in it of the accompanying hypoxic emotional distress. We addressed the issue by examining the associations among EEG, ventilation, and anxiety during progressive poikilocapnic hypoxia (end-point SaO2 75%) in 12 awake healthy volunteers (mean age 27.5 ±0.7 yr). All subjects hyperventilated in response to hypoxia and 3 of them had a high level of anticipatory anxiety that forced one person to discontinue the test. We failed to show any major effect of hypoxia on the EEG pattern analyzed by visual inspection or wavelet power spectra. Therefore, no relationship between the ventilatory and cortical activity responses to hypoxia could be established. Cortical activity changes appeared, however, in the subjects who experienced emotional distress during the test. These changes were apparent on an expanded analysis of the EEG signal by the use of the Lempel-Ziv complexity that takes into account the ordering of variations in the signal, rather than only the relative frequency of events analyzed by the Shannon entropy. The Lempel-Ziv complexity offers promise as a novel method for unraveling fine and otherwise unexpressed alterations in cortical bioelectrical activity.
Rationale and objective of the study: In the study of coordination of motor abilities, motor performance tests without examining the internal structure of the movement were used. The objective of this study was to examine the kinesthetic differentiation capacity level and to stimulate muscles during a test among basketball players in intermediate and specialist stages of training. Material and methods: Among ten basketball players from two equal groups at different level of advancement in sport, who play at different positions on the field, kinesthetic differentiation capacity was assessed by the „Basketball shooting with different balls” test. In order to assess the muscle involvement during the test, they were connected to the EMG amplifier. Results: More advanced basketball players obtained better results in the test, by an average of 7.4 point out of 60. Tested muscle bioelectric tension was lower by 21.8% in advanced players and the difference in the non-dominant hand was as high as 34.6%. Conclusions: The research indicates that advanced players obtain better level of kinesthetic differentiation and their average muscle bioelectric tension during throws is lower compared to beginner players. The difference in bio-electrical muscle tension in the time of throwing different balls was smaller in basketball players who are more advanced in training, and in both groups in the dominant hand. Mean values of EMG signal in a selected time interval show greater variability among the more advanced players.
Evaluation of biopotentials in the region of the amygdala of rats in the combined influence of alcohol and drugs, causing an imbalance of nitric oxide is described in this paper. Chronic alcoholism leads to structural morphological changes in the liver. A study of the amplitude of electrical activity showed that the electrical potential in the amygdala after 8 weeks chronic alcoholism was lower compared with normal rats. The frequency spectrum analysis showed decreased in the 2 times or more absolute spectral powers of all components. The relative spectral powers of its components: δ: θ: α: β was as a 2: 2: 2: 4. The use of sodium nitroprusside (donator of NO) together with the chronic consumption of ethanol reduces the effect of ethanol on low and high-frequence portion the performance of the bioelectrical activities spectrum in the amygdala. The use of non-selective blocker of NO-synthase – nitroarginine aggravated by the braking action of alcohol. The important role of nitric oxide in the development of adaptive-compensatory reactions of the damaged body is described. Our results may be useful to assess the contribution of NO in operation amygdala, conditions of chronic pathologies, and treatment of neuropsychiatric conditions, including diseases caused by alcohol abuse.
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