The aim of the study was to investigate the level of IgM and IgG class antibodies, specific to selected pathogens in foals at particular stages during their nursing period. The tests were conducted in a thoroughbred stable. Twelve sera from mares and 12 sera from foals were examined and total protein and gamma globulin fraction levels were estimated as well as the relative level of specific antibodies in IgM and IgG class using the ELISA test and expressed as the value of optical density (OD) against the following strains of bacteria antigens: Staphylococcus sciuri (1), Staphylococcus sciuri (2), Staphylococcus sciuri (3), Staphylococcus xylosus (4), Staphylococcus xylosus (5), Staphylococcus aureus (6), Staphylococcus aureus (7), Streptococcus equi subsp. Zooepidemicus (8), Streptococcus equi subsp. Zooepidemicus (9), Enterobacter aglomerans (10), Rhodococcus equi (11), Salmonella enterica ser Typhimurium (12). Traces of specific Ig R. equi were indicated in the foals sera before suckling whereas the OD value increased to 0.35 in sera following the absorption of colostrum. The profile of specific humoral response against environmental pathogens in nursing foals is dependent not only on antigenic moiety of the pathogen but also on the immunological status of the individual.
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