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1

Celiac disease autoimmunity

100%
Casado M. A. L., Lorite P., Ponce de Leon C., Palomeque T., Torres M. I.
Archivum Immunologiae et Therapiae Experimentalis
|
2018
|
tom 66
|
nr 6
2
Content available remote

How accurate is spirometry at predicting restrictive pulmonary impairment in children with myasthenia gravis

100%
Zielonka T., Kostera-Pruszczyk A., Ryniewicz B., Korczynski P., Szyluk B.
Journal of Physiology and Pharmacology. Supplement
|
2006
|
tom 57
|
nr 4
409-416
Myasthenia gravis (MG) is an autoimmune disorder of the neuromuscular junction. Clinical symptoms are caused by weakness and increased fatigability of various muscle groups. Myasthenia may lead to significant respiratory dysfunction. The aim of our study was to estimate lung function in children with MG. We tested 23 non-smoking patients (18 girls and 5 boys) aged 7-18 years. Whole-body plethysmography and spirometry were performed in all patients. In 33% of the patients a decrease in VC <80% of predicted value was observed (VC = 89 ±19%), but the analysis of TLC revealed restrictive pattern only in one patient (TLC = 102 ±17%). In more than 75% of the children the value of RV above 120% of predicted value was found (RV = 146 ±54%). Spirometric obstructive pattern measured by FEV1%VC <70% was not observed, although in 56% of the patients airway resistance was increased (Raw = 132 ±44%). In 45% of the patients a decrease of PEF (76 ±14%) was observed. In MG children true restrictive pulmonary impairment is rarely observed and a decrease in VC in these patents seems to result mainly from functional restriction provoked by an increase in RV. Spirometry is not an optimum method to assess functional changes in MG patients. The assessment of additional measures such as TLC, RV, and Raw is desirable.
3

The therapeutic potential of interleukin 10 in infection and inflammation

100%
Kumar A., Creery W. D.
Archivum Immunologiae et Therapiae Experimentalis
|
2000
|
tom 48
|
nr 6 Spec.Iss.
529-538
4

Clinical use and therapeutic potential of IVIG/SCIG, plasma-derived IgA or IgM, and other alternative immunoglobulin preparations

100%
Spath P. J., Schneider C., von Gunten S.
Archivum Immunologiae et Therapiae Experimentalis
|
2017
|
tom 65
|
nr 3
5

Activated and memory T lymphocytes in children with gaucher disease

100%
Zahran A. M., Eltayeb A. A., Elsayh K. I., Saad K., Ahmad F.-A., Ibrahim A. I. M.
Archivum Immunologiae et Therapiae Experimentalis
|
2017
|
tom 65
|
nr 3
6

Sjogren's syndrome: immunological response underlying the disease

100%
Brayer J. B., Humphreys-Beher M. G., Peck A. B.
Archivum Immunologiae et Therapiae Experimentalis
|
2001
|
tom 49
|
nr 5
7

Superantigens and their role in autoimmune disorders

100%
Schiffenbauer J.
Archivum Immunologiae et Therapiae Experimentalis
|
1999
|
tom 47
|
nr 1
8

Islet transplantation: factors in short-term islet survival

80%
Deters N. A., Stokes R. A., Gunton J. E.
Archivum Immunologiae et Therapiae Experimentalis
|
2011
|
tom 59
|
nr 6
9

Effect of aging on UVC-induced apoptosis of rat splenocytes

80%
Radziszewska E., Piwocka K., Bielak-Zmijewska A., Skierski J., Sikora E.
Acta Biochimica Polonica
|
2000
|
tom 47
|
nr 2
UVC-induced apoptotic symptoms such as morphological changes, DNA fragmentation, Bcl-2 and Bax protein expression were examined in primary splenocyte cultures from young (3 months) and old (24 months) rats. The activities of AP-1 and CRE transcription factors in UVC-irradiated splenocytes were also assessed. At 24 h after UVC irradiation 40% of cells derived from young rats were found to be apoptotic, which was twice as much as in splenocytes from old rats. Apoptosis in cells from old rats did not give typical symptoms like a DNA ladder and Bcl-2 protein downregulation, in contrast to splenocytes from young rats. No AP-1 transcription factor activity was found in UVC-irradiated splenocytes from old animals and only a trace activity in splenocytes from young animals. This indicates that, UVC-induced apoptosis in rat splenocytes is practically AP-1 independent and that cells from old rats are less sensitive to UVC irradiation than splenocytes from young rats.
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