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1

Androgens and FSH affect androgen receptor and aromatase distribution in the porcine ovary

100%
Slomczynska M., Szoltys M., Duda M., Sikora K., Tabarowski Z.
Folia Biologica
|
2003
|
tom 51
|
nr 1-2
2

Immunolocalization of aromatase and estrogen receptors in bank vole Leydig cells

86%
Schmalz B., Koziel E., Bilinska B.
Folia Histochemica et Cytobiologica
|
1999
|
tom 37
|
nr 2
3

Evidence for aromatase localization in cytoplasmic droplet of human immature ejaculated spermatozoa

86%
Rago V., Bilinska B., Palma A., Ando S., Carpino A.
Folia Histochemica et Cytobiologica
|
2003
|
tom 41
|
nr 1
4

The promoter(s) of the aromatase gene in male testicular cells

72%
Carreau S., Bourguiba S., Lambard S., Silandre D., Delalande C.
Reproductive Biology
|
2004
|
tom 04
|
nr 1
5

Immunohistochemical localization of androgen receptor and aromatase in the ovary of the pregnant pig

72%
Duda M., Burek M., Galas J., Koziol K., Koziorowski M., Slomczynska M.
Reproductive Biology
|
2004
|
tom 04
|
nr 3
6

Cytochrome P450 aromatase expression in canine nervous tissue: an immunohistochemical study

72%
Karahan S., Yarim M., Harada N.
Polish Journal of Veterinary Sciences
|
2008
|
tom 11
|
nr 4
347-352
The enzyme cytochrome P450 aromatase is responsible for conversion of androgens to estrogens. Estrogens have been implicated in neurophysiology and neuropathology. The present study investigated the presence of aromatase immunoreactivity in the temporal, parietal and occipital cortices, olfactory bulb, cerebellum, and choroid plexus of the normal dog. Aromatase immunoreactivity was localized exclusively in neurons in the cortices and olfactory bulb. Immunoreactivity was also present in a small number of astrocytes in the substantia alba of the cerebellum. In the cortical regions, immunoreactive neurons, morphologically identified as pyramidal cells, were found throughout Layer II down to Layer VI, but not all pyramidal neurons were immunoreactive. In the olfactory bulb, immunoreactive neurons were mainly observed in mitral cells and inner granular cell layers. In the cerebellum, immunoreactivity was present in neurons of the deep cerebellar nuclei and in some neurons of the molecular and granular cell layers. Immunoreactivity was also present in endothelial cells of the subarachnoid vessels and those adjacent to ventricles in the cortex. The presence of well defined cytoplasmic aromatase immunoreactivity in neurons, some astrocytes, and endothelial cells suggests estrogen involvement in CNS physiology and function in the dog. The presence of aromatase in ependymal cells lining cerebral ventricles and choroid epithelial cells suggests that these cells may be partially responsible for estrogen concentration in the cerebrospinal fluid.
7

Immunoexpression of androgen receptors and aromatase in testes of patient with Klinefelter's syndrome

72%
Kotula-Balak M., Bablok L., Fracki S., Jankowska A., Bilinska B.
Folia Histochemica et Cytobiologica
|
2004
|
tom 42
|
nr 4
8

The expression of androgen receptor, cytochrome P450 aromatase and FSH receptor mRNA in the porcine ovary

72%
Slomczynska M., Duda M., Slezak K.
Folia Histochemica et Cytobiologica
|
2001
|
tom 39
|
nr 1
9

Estrogens: a new player in spermatogenesis

58%
Carreau S., Silandre D., Bois C., Bouraima H., Galeraud-Denis I., Delalande C.
Folia Histochemica et Cytobiologica. Supplement
|
2007
|
tom 45
|
nr 1
5-10
10

The aromatase expression in myomas and myometriums of women in reproduction and perimenopausal age

58%
Madej P., Plewka A., Plewka D., Palen P., Nowaczyk G., Bogunia E., Marczynski J., Waloszek J.
Folia Histochemica et Cytobiologica
|
2009
|
tom 47
|
nr 3
11

New insights about the evaluation of human sperm quality: the aromatase example

58%
Galeraud-Denis I., Travert C., De Vienne C., Said L., Saad A., Carreau S.
Folia Histochemica et Cytobiologica
|
2009
|
tom 47
|
nr 5
12

Expression of steroidogenic enzymes in porcine polycystic ovaries

58%
Kozlowska A., Majewski M., Jana B.
Folia Histochemica et Cytobiologica
|
2009
|
tom 47
|
nr 2
257-264
13
Content available remote

Effects of ovariectomy in prepubertal goats

58%
Dessauge F., Finot L., Wiart S., Aubry J. M., Ellis S. E.
Journal of Physiology and Pharmacology. Supplement
|
2009
|
tom 60
|
nr 3
127-133
14
Content available remote

Modulatory effect of ghrelin in prepubertal porcine ovarian follicles

58%
Rak A., Gregoraszczuk E. L.
Journal of Physiology and Pharmacology
|
2008
|
tom 59
|
nr 4
781-793
Ghrelin is a novel growth hormone-releasing peptide, originally identified in rat stomach as an endogenous ligand of the growth hormone secretagogue receptor. Ghrelin is an important regulator of growth hormone secretion, food intake, and reproductive function. This study investigates whether or not ghrelin can modulate prepubertal pig ovary function, which was measured as ovarian estradiol secretion, aromatase activity, cell proliferation, and apoptosis. To investigate this, ovarian cells were co-cultured with four different doses of ghrelin (100, 250, 500, and 1000 pg/ml) for 48 h. Culture media samples were collected, and estradiol levels were determined, while aromatase expression was measured in the cultured cells. Cell apoptosis was measured by determination of caspase-3 activity, DNA fragmentation and TUNEL assay. Ghrelin in 250 and 500 pg/ml doses stimulated estradiol secretion. At all doses ghrelin stimulated aromatase activity and protein expression. Moreover, ghrelin increased cell proliferation and decreased apoptosis. This study provides novel evidence that ghrelin has a modulatory effect in the ovary. We suggest two mechanisms that explain how ghrelin acts on estradiol secretion: 1) ghrelin directly influences aromatase activity and protein expression; 2) ghrelin stimulates cell proliferation and antiapoptotic actions.
15

Estrogens - male hormones?

58%
Carreau S.
Folia Histochemica et Cytobiologica
|
2003
|
tom 41
|
nr 3
16

The compounds from the hollyhock extract [Althaea rosea Cav.var.nigra] affect the aromatization in rat testicular cells in vivo and in vitro

58%
Papiez M., Gancarczyk M., Bilinska B.
Folia Histochemica et Cytobiologica
|
2002
|
tom 40
|
nr 4
17

The influence of interleukin-1 and interleukin-6 on expression of proteins involved in steroidogenesis in Leydig cells and on their apoptosis or necrosis in vitro

58%
Sawinski P., Lukaszyk A.
Folia Histochemica et Cytobiologica
|
2002
|
tom 40
|
nr 2
18
Content available remote

DDT- and DDE-induced disruption of ovarian steroidogenesis in prepubertal porcine ovarian follicles: a possible interaction with the main steroidogenic enzymes and estrogen receptor ß

58%
Wojtowicz A. K., Kajta M., Gregoraszczuk E. L.
Journal of Physiology and Pharmacology
|
2007
|
tom 58
|
nr 4
We evaluated impact of DDT isomers, o, p'- DDT [1, 1-dichloro-2, 2-bis (p, p'-chlorophenyl) ethylene] and p, p'-DDT [1, 1, 1-trichloro-2, 2-bis (p-chlorophenyl) ethane], and their metabolites, o, p'-DDE and p, p'-DDE, on ovarian steroidogenesis. All these compounds, except for p, p'-DDT, demonstrated estrogenic effects on steroid secretion in co-cultures of porcine prepubertal granulosa and theca cells. p,p'-DDT decreased progesterone and estradiol release, which was reversed by the addition of testosterone. In contrast, o, p'-DDT inhibited progesterone secretion with parallel stimulation of basal and testosterone-stimulated estradiol release. DDEs stimulated progesterone and estradiol secretion. The fluorometric assay confirmed that p,p'-DDE, o,p'-DDT, and o,p'-DDE stimulated aromatase activity. Western blots indicated that o,p-DDT and o,p'-DDE diminished the expression of estrogen receptor ß (ERß). This study demonstrated the isomer-dependent action of DDT in pig ovarian cells. We propose that DDT could disrupt ovarian steroidogenesis either by interfering with main steroidogenic enzymes or affecting ERß.
19

The TRAF2 and TRAF6 expression in myomas and myometrium of women in reproduction and perimenopausal age

51%
Plewka A., Madej P., Plewka D., Nowaczyk G., Morek M., Bogunia E., Ciupinska-Kajor M., Sieron-Stoltny K.
Folia Histochemica et Cytobiologica
|
2010
|
tom 48
|
nr 3
20

Cytochrome P450 aromatase in male germ cells

51%
Carreau S., Levallet J.
Folia Histochemica et Cytobiologica
|
1997
|
tom 35
|
nr 4
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